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Abstract

Nutritional supplements such as iron, folic acid, calcium, multi – vitamin, and ascorbic acid are commonly prescribed in health care settings. However, irrational, or inappropriate use of these supplements can lead to adverse effects, unnecessary costs, and contribute to the development of drug resistance in some cases. In government hospitals, where resources are often limited, ensuring that supplements are prescribed rationally is crucial for both improving patient outcomes and optimizing healthcare resources. The aim of the study is Rational use of nutritional supplements in a government hospital: A Cross – Sectional Analysis. This is a Cross – sectional, observational study conducted in APPVP Hospital, Narasaraopet, over a period of 6 months, A total of 200 patients were prescribed with nutritional supplements. According to the study, the overall patient’s demographics of sex distribution in the study are, 90 patients were males (45%) and 110 patients were females (55%). A wide range of patients were involved in the study whose age group ranges from 18 to 60 years and above. In our study we concluded that a notable portion of prescriptions for multivitamins and Ascorbic acid were not in accordance with established guidelines.

Keywords

Adverse effects, Nutritional supplements, Rational, Irrational, Prescriptions

Introduction

Nutritional supplements, including vitamins, minerals, and herbal extracts, play a significant role in addressing dietary deficiencies and supporting overall health. They are particularly beneficial for populations with specific needs, such as pregnant women, older adults, and individuals with restricted diets or chronic illnesses. For example, folic acid supplementation during pregnancy reduces the risk of neural tube defects, while vitamin D is vital for those with limited sun exposure to maintain bone health and immune function1. The rational use of supplements involves evidence-based, individualized approaches that prioritize safety and efficacy. Professional guidance from healthcare providers, alongside laboratory assessments, can help identify specific nutrient deficiencies and recommend suitable supplementation2.

Selecting high-quality products from reputable manufacturers is critical to ensure consistency and bioavailability. Adherence to recommended dosages is essential to prevent potential risks, such as toxicity or adverse interactions with medications. It is equally important to educate consumers about the risks of indiscriminate use, often fuelled by misconceptions or aggressive marketing. Supplements should complement a balanced diet rather than replace it, promoting long-term health and well-being. In conclusion, when used judiciously and with professional guidance, nutritional supplements can enhance health outcomes while minimizing unnecessary risks and costs.3,4

METHODOLOGY

  • Study site       : APPVP Area Hospital, Narasaraopet, Andhra Pradesh
  • Study Design : Cross – sectional study
  • Study period  : 6 months.
  • Study criteria :
  1. Inclusion criteria : 
  • Patients who were prescribed at least one of the specified nutritional supplements
  • Outpatient cases
  1. Exclusion criteria :
  • Patient with incomplete prescriptions or follow up details
  • Patients receiving non – oral supplementations
  • Source of data : Outpatient records and medical records department and Patient interviews whenever necessary.

RESULT

Table 1: Gender Distribution

S. no

Gender

No. of patients

Percentage (%)

1

Males

90

45%

2

Females

110

55%

Fig. 1 - Gender distribution

Table 2: Age in distribution

Age in groups

No. of patients

Percentage (%)

18 - 30

36

18%

31 - 45

48

24%

46 - 60

56

28%

Above 61

60

30%

 

Fig. 2 – No. of patient’s vs Age Group

Table 3 : Prevalence of supplements prescribed

Supplements

No. of patients

Percentage (%)

Iron

70

35%

Folic acid

20

10%

Calcium

40

20%

Multi vitamin

30

15%

Ascorbic acid

40

20%

 

Fig. 3 – No. of patient’s vs Prevalence of Supplement’s

Table 4 : Indications for supplementations

Supplements

Indication

No. of patients

Percentage (%)

Iron

Anemia

28

14%

Post surgery recovery

6

3%

Pregnancy

6

3%

Folic acid

Anemia

12

6%

Pregnancy

22

11%

Malabsorption

6

6%

Calcium

Osteoporosis

22

11%

Vit. D deficiency

10

5%

Pregnancy

8

4%

Multi vitamin

General health

16

8%

Pregnancy

14

7%

Malnutrition

10

5%

Ascorbic acid

Immunity support

20

10%

Scurvy prevention

8

4%

General health

12

6%

 

Fig . 4 – Indication of Supplement’s vs No. of Patients

Table 5 : Rationality of supplement use

Supplements

Adherent cases

Irrational cases

No of Patients

Percentage (%)

Iron

44

9

50

25%

Folic acid

38

12

50

25%

Calcium

41

6

50

25%

Multi vitamin

21

9

30

15%

Ascorbic acid

18

2

20

10%

TOTAL

162

38

200

 

Fig. 5 – No. of patient’s vs supplement’s

DISCUSSION

In our present study titled “Rational use of Nutritional Supplements in a Government Hospital: A Cross – Sectional Analysis” a total no. of 200 patients were included out of which 90 (45%) are male patients and 110 (55%) were female patients. The purpose of this study is to assess the rational use of iron, folic acid, calcium, multivitamins, and ascorbic acid in a government hospital setting by evaluating the prescription patterns, adherence to guidelines, and patient outcomes. The study found that iron, calcium, folic acid and ascorbic acid were the most commonly prescribed supplements, with iron and folic acid being the most frequently prescribed for anaemia and pregnancy-related conditions. A significant proportion of prescriptions were rational, following established clinical guidelines, but a considerable number of prescriptions, particularly for multivitamins and Ascorbic acid, were not in line with guidelines. These prescriptions may indicate over use or misapplication of supplements in patients without clear deficiencies. Despite general adherence to recommendations, there is still potential for improvement in minimising the irrational use of supplements. Similar studies in other healthcare settings, including public hospitals, show a high prevalence of irrational supplementation, particularly for multivitamins and folic acid. This is often due to a lack of diagnostic testing and inappropriate prescribing practices. Patients should be educated about the importance of following prescriptions as directed and about the risks associated with taking supplements without clear medical indications.

Health care systems reforms : Implementing electronic health records and decision support systems could improve adherence to evidence-based prescribing guidelines and reduce errors.

Limitations :

  1. The study is limited by its cross-sectional nature, which does not allow for long-term outcome measurement.
  2.  The study was conducted in a single hospital, limiting its generalizability to other regions or countries.

CONCLUSION

The study highlighted that while the majority of nutritional supplement prescriptions were rational, a notable portion of prescriptions for multivitamins and Ascorbic acid were not in accordance with established guidelines. This indicates a need for improvements in prescribing practices and patient education in the government hospital setting. Rational supplementation is essential not only for improving patient outcomes but also for reducing unnecessary costs in public healthcare.

CONFLICT OF INTEREST: Nill

ACKNOWLEDGEMENT: The authors express their gratitude to the inquisitive individuals who assisted and encouraged us in our research work.

REFERENCES

  1. Axon DR, Vanova J, Edel C, Slack M. Dietary supplement use, knowledge, and perceptions among student pharmacists. Am J Pharm Educ. 2017;81(5):92.
  2. Wierzejska RE. Dietary Supplements-For Whom? The Current State of Knowledge about the Health Effects of Selected Supplement Use. Int J Environ Res Public Health. 2021 Aug 24;18(17):8897.
  3. Smith, J., & Clark, A. (2021). "Trends in Nutritional Supplement Prescriptions in Public Healthcare: A Systematic Review". Journal of Public Health, 45(2), 78-85.
  4. Saha S, Pandya A, Kandre Y, Raval D, Saxena D. Cross-Sectional Analysis of Nutritional Status, Knowledge, and Uptake of Nutritional Services Among Adolescent Girls in Western India. Adolesc Health Med Ther. 2021 Dec 14;12:117-125.

Reference

  1. Axon DR, Vanova J, Edel C, Slack M. Dietary supplement use, knowledge, and perceptions among student pharmacists. Am J Pharm Educ. 2017;81(5):92.
  2. Wierzejska RE. Dietary Supplements-For Whom? The Current State of Knowledge about the Health Effects of Selected Supplement Use. Int J Environ Res Public Health. 2021 Aug 24;18(17):8897.
  3. Smith, J., & Clark, A. (2021). "Trends in Nutritional Supplement Prescriptions in Public Healthcare: A Systematic Review". Journal of Public Health, 45(2), 78-85.
  4. Saha S, Pandya A, Kandre Y, Raval D, Saxena D. Cross-Sectional Analysis of Nutritional Status, Knowledge, and Uptake of Nutritional Services Among Adolescent Girls in Western India. Adolesc Health Med Ther. 2021 Dec 14;12:117-125.

Photo
Bandarupalli Sri Sirisha
Corresponding author

Mederametla Anjamma Mastan Rao College of Pharmacy, Narasaraopet

Photo
Mareedu Harish
Co-author

Mederametla Anjamma Mastan Rao College of Pharmacy, Narasaraopet

Photo
Dr. M. Prasad Rao
Co-author

Mederametla Anjamma Mastan Rao College of Pharmacy, Narasaraopet

Photo
Dr. Y. Narasimha Rao
Co-author

Mederametla Anjamma Mastan Rao College of Pharmacy, Narasaraopet

Bandarupalli Sri Sirisha*, Mareedu Harish, Dr. M. Prasad Rao, Dr. Y. Narasimha Rao, Rational Use of Nutritional Supplements in A Government Hospital: A Cross - Sectional Analysis, Int. J. of Pharm. Sci., 2025, Vol 3, Issue 2, 1893-1897. https://doi.org/10.5281/zenodo.14913738

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