Department of Pharmaceutical Quality Assurance, PRES College of Pharmacy (Women’s), Chincholi, Nashik-422102
The most frequent modifiable risk factor for death and disability is hypertension. Other modifiable risk factors include stroke, accelerated coronary and systemic atherosclerosis, heart failure, chronic kidney disease, lowering blood pressure with antihypertensive medications, and lowering the prevalence of cardiovascular disease. The 2017 American college of cardiology (ACC)/American heart association (AHA) hypertension recommendations define hypertension as systolic blood pressure (BP) greater than 130 mmHg or diastolic blood pressure (BP) less than 80 mmHg. In patients with CHD, CHF, following kidney transplantation, diabetes mellitus, and stroke, BP should be less than 130/80 mmHg. The patient was advised to modify their lifestyle by reducing their salt intake, losing weight if they were overweight, exercising regularly, drinking alcohol in moderation, and consuming more potassium-rich foods. The first antihypertensive medication should often come from one of the four types listed below: calcium channel blockers, thiazide diuretics, ACE inhibitors, and ARBs. These drugs have been found to lower cardiovascular events. Renal denervation and baroreflex activation therapy are the two interventional methods utilised in clinical practise to treat a variety of treatment-resistant hypertensions. Carotid body ablation and the implantation of an AVF are two other interventional techniques, although none of them can stop the progression of cardiovascular disease or a hypertensive patient's mortality.
Varsha Pangale*, Neha Gaikwad, Samiksha Aher, A systematic review on Hypertension and conditions related to thereof, Int. J. in Pharm. Sci., 2024, Vol 1, Issue 4, 166-185. https://doi.org/10.5281/zenodo.7847427