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  • Multifarious Effects Of Benidipine In Vitro And In Vivo A Review

  • 1M Pharm, Assistant Professor, Department of Pharmacy Practice, PSG College of Pharmacy, 2295+PCJ, Peelamedu, Avinashi Rd, Coimbatore, Tamil Nadu- 641004.
    2-4Doctor of Pharmacy, Student, PSG College of Pharmacy,2295+PCJ, Peelamedu, Avinashi Rd, Coimbatore, Tamil Nadu- 641004.
     

Abstract

BACKGROUND: Worldwide, around 25% of individuals suffer from Hypertension is an elevated blood pressure in arteries. Benidipine is an anti-hypertensive drug and it is a long-acting agent. It blocks all the L,N and T-type calcium channels. MAIN TEXT: Other than anti-hypertensive action, benidipine has other pharmacological effects. In-vivo basic research has shown that benidipine has anti-oxidative properties,stimulatesnitric oxide production, promotes osteoblast differentiation, prevents the formation of mesangial cells, prevents the proliferation of smooth muscles in the vascular system, and safeguards the kidney and muscular tissue of the heart. The purpose of the review is to study the effects of benidipine in in-vitro and in-vivo and its beneficial actions in different disease states. CONCLUSION: Benidipine is therapeutically well effective such as Reno-protective, Cardioprotective, and Neuro-protectivehas a stronger inhibitory impact on ureteric contractility in the distal ureter also effective in osteogenesis and osteoporosis conditions

Keywords

Hypertension, Benidipine, Cardio-protective, Reno-protective, Neuro-protective, osteoporosis

Reference

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Vishnupriya S.
Corresponding author

M Pharm, Assistant Professor, Department of Pharmacy Practice, PSG College of Pharmacy, 2295+PCJ, Peelamedu, Avinashi Rd, Coimbatore, Tamil Nadu- 641004.

Photo
Dhinesh M.
Co-author

Doctor of Pharmacy, Student, PSG College of Pharmacy,2295+PCJ, Peelamedu, Avinashi Rd, Coimbatore, Tamil Nadu- 641004.

Photo
Anjitha P. S.
Co-author

Doctor of Pharmacy, Student, PSG College of Pharmacy,2295+PCJ, Peelamedu, Avinashi Rd, Coimbatore, Tamil Nadu- 641004.

Photo
Eniya A. A.
Co-author

Doctor of Pharmacy, Student, PSG College of Pharmacy,2295+PCJ, Peelamedu, Avinashi Rd, Coimbatore, Tamil Nadu- 641004.

Vishnupriya S , Dhinesh M. , Anjitha P. S. , Eniya A. A. , Multifarious Effects Of Benidipinein Vitro And In Vivo - A Review, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 2, 676-683. https://doi.org/10.5281/zenodo.10702076

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