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  • Preparation And Standardization Of Ayurvedic Nindra Vati

  • 1Department of Pharmacognosy, Shivam Pharmaceutical Studies & Research Center, Valasan, Gujarat, India
    2Department of Pharmaceutical Chemistry, A.R. College of Pharmacy & G.H. Patel Institute of Pharmacy, Vallabh Vidyanagar, Gujarat, India
     

Abstract

The present work deals with preparation and standardization of Nindra Vati for treatment of insomnia patients. After evaluating crucial macroscopical and microscopical parameters, vati’s were formulated. Vati’s were evaluated from necessary post-evaluation parameters. Average weight and % weight variation found to be 10.1 ± 10.9 mg and 1.4 % respectively. Hardness and thickness are within the pharmacopeial standards. % friability and disintegration time were observed 0.9 % and 20.30 ± 0.50 min. Total ash, acid soluble ash and water-soluble ash values are 15%, 5% and 5.4% respectively. Water soluble and alcohol soluble extractive values were 12.8% and 5.7%. The formulated nindra vati’s are novel formulation and values of evaluations parameters are within the pharmacopeial standards.

Keywords

Nindra vati, formulation, evaluation

Reference

  1. Patadiya N, Dumpala R. A High profile review on new oral clotting factor xa inhibitor: betrixaban. European Journal of Pharmaceutical and Medical Research. 2021; 8(1): 239-247.
  2. Kolekar T, Patadiya N. Dissolution Enhancement Technique: Self-Emulsifying Drug Delivery Systems (SEDDS). International Journal of Institutional Pharmacy and Life Sciences. 2020; 10(6):25-39.
  3. Kolekar T, Patadiya N. Self-emulsifying drug delivery Systems (SEDDS): A novel dissolution enhancement technique. International Journal of Trend in Innovative Research .2020; 2(5): 10-20.
  4. Devprakash S, Srinivasan K, Subburaju T, Sachin S. Antimicrobial activity of alcoholic and aqueous extracts of Vetiveria zizanioides. J Phar Res. 2011; 4(5):1343-1344
  5. Nahak G and Sahu RK. Phytochemical evaluation and antioxidant activity of Piper cubeba and Piper nigrum. J Applied Phr. Sci. 2011; 1(8): 153-157.
  6. Sapam R, Kalita P, Sarma P, Talukdar N and Das H. Screening of phytochemicals and determination of total phenolic content, anti-oxidant, and antimicrobial activity of methanolic extract of Piper nigrum leaves. Indo American Journal of Pharmaceutical Research. 2018; 8(2): 1354-1360
  7. Nwofia G, Kelechukwu C, Nwofia B. Nutritional composition of some Piper nigrum (L.) accessions from Nigeria. Int J Med Arom Plants. 2013; 3:247–54 21.
  8. Srinivasan K. Black Pepper and its Pungent Principle-Piperine: A Review of Diverse Physiological Effects. Critical reviews in food science and nutrition. 2007; 47:735-48. 10.1080/10408390601062054.
  9. Shilpa P. Nikunj P, Pooja M, Rikin P. Preparation and standardization of chitrakadi vati. J. Pharm. Sci. Innov. 2022; 11 (3):28-35.http://dx.doi.org/10.7897/2277-4572.113230.
  10. Makvana P, Patadiya N, Baria D. Design, molecular docking, in-silico admet prediction, synthesis and evaluation of novel quinazoline derivatives as factor XA inhibitors. Int. Res. J. Pharm. 2022; 13(3): 30-37. http://dx.doi.org/10.7897/2230-8407.1303187
  11. Patadiya N. Steroids: classification, nomenculture and stereochemistry. International Journal of Universal Pharmacy and Bio Sciences. 2020; 9(5): 28-38.
  12. Patel R, Darji J, Patadiya N, Thummar M. Development and evaluation of medicated chewing gum of raloxifene hydrochloride. International Journal of Pharmaceutical and Biological Science Archive. 2021; 9(3): 01-12.
  13. Patadiya N, Vaghela V, Padhra Saurav. Optimisation of synthetic condition for 2’hydroxy Chalcone by using mixture design. Asian J. Research Chem. 2023; 16(6): 417-422. doi: 10.52711/0974-4150.2023.00068.
  14. Soni D, Patadiya N. A wonderful hormone: estrogen. International Journal of PharmaO2. 2020; 2(5):0362-0368.
  15. Dumpala R, Patel J, Patadiya N, Patil C. Solubility and dissolution enhancement of Erlotinib by liquisolid compact technique. International Journal of PharmaO2. 2020; 2(4): 0271-0290.
  16. Patadiya N, Vaghela V. A novel and eco-friendly method for synthesis of 3-benzylidene-2-phenylchroman-4-one analogs. Asian J. Research Chem. June 2022; 15(3): 195-199. doi: 10.52711/0974-4150.2022.00033.
  17. Patadiya N, Vaghela V. Design, in-silico ADME study and molecular docking study of novel quinolone-4-on derivatives as factor xa inhibitors as potential anti-coagulating agents. Asian J. Pharm. Res. Sept 2022. 12(3): 207-211. doi: 10.52711/2231-5691.2022.00034
  18. Patadiya N, Vaghela V. An efficient method for synthesis of flavanone. Asian J. Pharm. Res. Sept 2022. 12(3): 221-224. doi: 10.52711/2231-5691.2022.00039
  19. Patadiya N, Vaghela V. An optimized method for synthesis of 2’hydroxy chalcone. Asian J. Research Chem. 2022; 15(3): 210-212. doi: 10.52711/0974-4150.2022.00036
  20. Nikunj P, Nikita P, Vipul V. A review on enzyme inhibitors. Int. Res. J. Pharm. 2021;12 (6): 60-66.http://dx.doi.org/10.7897/2230-8407.1206145
  21. Nikunj P and Rajesh D. A high profile review on new oral clotting factor xa inhibitor:betrxaban. European Journal of Pharmaceutical and Medical Research. 2021 8(1), 239-247

Photo
Nikunj Patadiya
Corresponding author

Department of Pharmaceutical Chemistry, A.R. College of Pharmacy & G.H. Patel Institute of Pharmacy, Vallabh Vidyanagar, Gujarat, India

Photo
Shilpa Patel
Co-author

Department of Pharmacognosy, Shivam Pharmaceutical Studies & Research Center, Valasan, Gujarat, India

Shilpa Patel, Nikunj Patadiya , Preparation And Standardization Of Ayurvedic Nindra Vati, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 2, 403-409. https://doi.org/10.5281/zenodo.10673390

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