Archive

  • To Study Invitro Anticancer activity Brine shrimp Lethality and Anticoagulant Activity of Tribulus terrestris L. Seeds
  • Department of pharmaceutical chemistry, Sahyadri college of pharmacy Methawade, Sangola, Dist. Solapur, Maharashtra, India.

Abstract

The ethanol extract and aqueous extract from that study. The Tribulus terrestris Seed was then subjected to phytochemical testing, which revealed pharmacological effects such as anticancer activity as measured by the brine shrimp Lethality Bioassay and anticoagulant activity. Aqueous extract has been shown to be more active than ethanol extract in comparison studies. Tribulus terrestris extracts were effective against brine prawns with LC50 values of coc.100, 200, 400, and 800 (g/mL), according to in vitro anticancer activity cytotoxicity evaluation results. The in vitro anticoagulant effects of various Tribulus terrestris extracts in different concentrations of 25, 50, 100, and 200 mg/ml were examined using plasma, obtained from blood samples of healthy individuals. Saline in distilled water was used as a positive control and EDTA was used as a negative control when measuring PT.

Keywords

Anticancer activity, Anticoagulant Activity, Tribulus terrestris L.

Reference

  1. Holbrook AM, et.al. 2005, Systematic overview of warfarin and its drug and food interactions. Arch. Intern. Med.165(10):1095-106.
  2. Dr. Khandelwal k. r book of practical pharmacognosy, Nirali publication,147
  3. Sridhar K, et.al., 2016, Phytochemical Screening and GC-MS Analysis of Ethanolic extract of Tribulus terrestris, International Journal of Pharmacology Research, 6 (1) 44-50
  4. Nyati Paridhi, And Bhargava Shilpa, 2022, Study on the Phytochemical Analysis and determination of secondary metabolites on seed of Tribulus terrestris, International Journal of Current Pharmaceutical Review and Research 14(3); 135-142
  5. Khaled A. and Tawaha, 2006, Cytotoxicity Evaluation of Jordanian Wild Plants using Brine Shrimp Lethality Test, J. J. Appl. Sci., 8, (1), 12-17.
  6. Lilybeth F. et.al, 2013 Brine Shrimp Lethality Assay of the Ethanolic Extracts of Three Selected Species of Medicinal Plants from Iligan City, Philippines International Research Journal of Biological Sciences, 2(11), 74-77.
  7. Mclaughlin J.L.,1991, Methods in plant biochemistry, K. Hostettman (ed.), London: Academic press, 6: 1.
  8. Asaduzzaman Md, et.al 2015 cytotoxic (brine shrimp lethality bioassay) and antioxidant investigation of barringtonia acutangula, International Journal of Pharma Sciences and Research. 6(8) ,1179-1185)
  9. Jabbar S, et.al 2004 bioactivity studies of the individual ingredients of the dashamularishta, Pakistan journal of pharmaceutical sciences 17, (1).9-17.
  10. Rabia Naz, et.al 2017, Antimicrobial activity, toxicity and anti-inflammatory potential of methanolic extracts of four ethnomedicinal plant species from Punjab, Pakistan, BMC Complementary and Alternative Medicine 17:302
  11. Ramya D, et.al 2017 In vitro anticoagulant activity of Nelumbo nucifera leaf extracts on normal healthy blood plasma, International Journal of Green Pharmacy, 11 (3) 166.
  12. Biggs R, and McFarlane R.1962 Human blood coagulation and their disorders. Blackwell scientific Publications, Oxford. 1962;430- 436.

image
Kaufiya D Sayyad
Corresponding author

Department of pharmaceutical chemistry, Sahyadri college of pharmacy Methawade, Sangola, Dist. Solapur, Maharashtra, India.

image
Ashpak M. Tamboli
Co-author

Department of pharmaceutical chemistry, Sahyadri college of pharmacy Methawade, Sangola, Dist. Solapur, Maharashtra, India.

image
Manoj S. Patil
Co-author

Department of pharmaceutical chemistry, Sahyadri college of pharmacy Methawade, Sangola, Dist. Solapur, Maharashtra, India.

Kaufiya D Sayyad*, Ashpak M. Tamboli, Manoj S. Patil, To Study In - vitro Anticancer activity (Brine shrimp Lethality) and Anticoagulant Activity of Tribulus terrestris L. Seeds, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 9, 192-196. https://doi.org/10.5281/zenodo.8331531

More related articles
Advancements In Calcium Carbonate Nanoparticles: N...
Mohan raj U., Padmapreetha. J., Vignesh R., Arun Prasath S., Nav...
A Review Article on Buccal Patches ...
Bharti kokate , Khandare Rajeshree, ...
In Vitro Evaluation of Antispasmodic Activity Of Rhizomes Of Bergenia Ligulata...
Ananya Bhattacharjee, Abhijit Mishra, Ankita Adhikari, Benazeer Ali, Pratham Gurung, ...
Nanosponges: A Modern Formulation Approach In Drug Delivery System...
Siddhi J. Rakibe, Kanchan B. Benkule, Janhvi D. Borse, Ashish Y. Pawar, ...
Related Articles
Pneumonia And Types & An Over View On Aspiration Pneumonia...
P. Shabeera, V. Mounika, S. Rasheed, A. Shajara Rahin, B. G. Hemanth, ...
A Review On Herbal Mosquito Repellent ...
Jayesh R. Patil, Shreya M. Nalawade , Raj Y. Pandya , Harshada S. Patil, ...
All Rounder Of Ayurveda Tinospora Cordifolia...
Shital Devkar , Suvarna Deshmukh , Sourabh Patil , Shreyash Koli , Prachi L. Khochage , Nilesh B. Ch...
Advancements In Calcium Carbonate Nanoparticles: Novel Strategies For Osteomyeli...
Mohan raj U., Padmapreetha. J., Vignesh R., Arun Prasath S., Navyasree S. M., ...
More related articles
Advancements In Calcium Carbonate Nanoparticles: Novel Strategies For Osteomyeli...
Mohan raj U., Padmapreetha. J., Vignesh R., Arun Prasath S., Navyasree S. M., ...
A Review Article on Buccal Patches ...
Bharti kokate , Khandare Rajeshree, ...
Advancements In Calcium Carbonate Nanoparticles: Novel Strategies For Osteomyeli...
Mohan raj U., Padmapreetha. J., Vignesh R., Arun Prasath S., Navyasree S. M., ...
A Review Article on Buccal Patches ...
Bharti kokate , Khandare Rajeshree, ...