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Abstract

Antibiotics are drugs used to prevent and treat infectious diseases in humans, animals, and plants. The problem of antibiotic resistance is linked to the overuse and abuse of these drugs and the inability of the pharmaceutical industry to create new drugs due to difficult regulatory requirements and diminished financial incentives. Many of these bacteria currently impose a significant clinical and financial burden on patients, families, and the U.S. healthcare system. The rapid emergence of resistant bacteria throughout the world jeopardizes the effectiveness of antibiotics that have transformed medicine and saved millions of lives. The molecular mechanisms of resistance to the evolution of bacteria genetics and biochemistry prove that it is difficult to maintain effective antibiotic activity, particularly due to the resistance shown to such problems.

Keywords

Antibiotic resistance, Antibiotic, DNA.

Reference

  1. Frieri, Marianne, Krishan Kumar, and Anthony Boutin. "Antibiotic resistance." Journal of infection and public health 10.4 (2017): 369-378.
  2. Larsson, D. G., and Carl-Fredrik Flach. "Antibiotic resistance in the environment." Nature Reviews Microbiology 20.5 (2022): 257-269.
  3. MacGowan, Alasdair, and Emily Macnaughton. "Antibiotic resistance." Medicine 45.10 (2017): 622-628.
  4. Levy, Stuart B. "The challenge of antibiotic resistance." Scientific American 278.3 (1998): 46-53.
  5. Neu, Harold C. "The crisis in antibiotic resistance." Science 257.5073 (1992): 1064-1073.
  6. Munita, Jose M., and Cesar A. Arias. "Mechanisms of antibiotic resistance." Virulence mechanisms of bacterial pathogens (2016): 481-511.
  7. D’Costa, Vanessa M., et al. "Antibiotic resistance is ancient." Nature 477.7365 (2011): 457-461.
  8. McArthur, Andrew G., et al. "The comprehensive antibiotic resistance database."Antimicrobial agents and chemotherapy 57.7 (2013): 3348-3357.
  9. Davies, Julian, and Dorothy Davies. "Origins and evolution of antibiotic resistance." Microbiology and molecular biology reviews 74.3 (2010): 417-433.
  10. Livermore, David M. "Minimising antibiotic resistance." The Lancet infectious diseases 5.7 (2005): 450-459.
  11. Sabtu, N., D. A. Enoch, and N. M. Brown. "Antibiotic resistance: what, why, where, when and how?." British medical bulletin 116.1 (2015).
  12. Aminov, Rustam I. "The role of antibiotics and antibiotic resistance in nature." Environmental microbiology 11.12 (2009): 2970-2988.
  13. Chokshi, Aastha, et al. "Global contributors to antibiotic resistance." Journal of global infectious diseases 11.1 (2019): 36.
  14. Kapil, Arti. "The challenge of antibiotic resistance: need to contemplate." Indian Journal of Medical Research 121.2 (2005): 83.
  15. Martinez, Jose Luis, et al. "A global view of antibiotic resistance." FEMS microbiology reviews 33.1 (2008): 44-65.

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Rushikesh S. Wable
Corresponding author

Department of Pharmacology, Delonix Society’s Baramati College of Pharmacy, Barhanpur, Baramati Pune Maharashtra, India.

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Vasant K. Jamble
Co-author

Department of Pharmacology, Delonix Society’s Baramati College of Pharmacy, Barhanpur, Baramati Pune Maharashtra, India.

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Akanksha V. More
Co-author

Department of Pharmacology, Delonix Society’s Baramati College of Pharmacy, Barhanpur, Baramati Pune Maharashtra, India.

: Rushikesh S. Wable, Vasant K. Jamble, Akanksha V. More, Antibiotic Resistance: Global Threat To Public Health, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 2, 1-9. https://doi.org/10.5281/zenodo.10602984

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