Highlights of Vol 3 | Issue 8 | 2025
The modern skincare and cosmeceutical industries are experiencing a paradigm shift toward plant-based, eco-friendly formulations. Among emerging topical systems, hydrogel...
10.5281/zenodo.17008937 
The present study investigates the antimicrobial potential of Morinda citrifolia through in vitro evaluation and molecular docking. Antimicrobial assays revealed signific...
10.5281/zenodo.17008835 
This work was undertaken to design and assess a gastroretentive floating drug delivery system (GRDDS) for Ondansetron, a selective 5-HT? receptor blocker widely e...
10.5281/zenodo.17008216 
“ AI is likely to be either the best or worst thing to happen to humanity.” -Elon Musk. AI has started to improve its application across different sectors, with the p...
10.5281/zenodo.17008073 
The Rubiaceae family tree Mitragyna parvifolia, (Roxb.) Korth., commonly referred to as Kadamba, Kaim, has a long history of usage in Ayurvedic, Unani, & folk medicine. H...
10.5281/zenodo.17008013 
The aim of this review is to explore and evaluate oral gel formulations, utilizing both natural and synthetic polymers. Oral gels serve as effective drug delivery systems...
10.5281/zenodo.17007947 
Cyclodextrin (CD)-based self-assembling hydrogels have gained significant devotion in biomedical, pharmaceutical, and material science due to their unique ability to form...
10.5281/zenodo.17007127 
Oral ulcers are frequently caused by trauma, systemic problems or idiosyncratic reasons, infections thus lead to more painful condition which impacts the mucosal lining o...
10.5281/zenodo.17006521 
Pyrimidine-based derivatives represent a crucial class of nitrogen-containing heterocyclic compounds with broad pharmacological and synthetic relevance. These six-membere...
10.5281/zenodo.17004891 
A principal drawback of conventional drug delivery approaches lies in their limited capacity to achieve selective targeting, often resulting in diminished therapeutic eff...
10.5281/zenodo.17004392 
PURPOSE: The main aim of the study was to evaluate the antibiotics usage trends in a tertiary care setting through drug utilization evaluation technique. METHODOLOGY: It ...
10.5281/zenodo.17004019 
In the current investigations, mouth dissolving tablets (MDT) were developed by using natural superdisinegranting agent isolated from Plantago Ovata Seeds. Direct compres...
10.5281/zenodo.17002967 
Setplet syrup, which contains Carica papaya, elemental iron, folic acid, cobalt, copper, vitamin B12, and vitamin C, is a unique platelet booster with hematinic propertie...
10.5281/zenodo.16993917 
Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon characterized by recurrent mucosal ulceration, diarrhea, abdominal pain, and weight loss. Conventi...
10.5281/zenodo.16993865 
Niosomes are vesicular systems based on non-ionic surfactants that have gained recognition as a promising alternative to liposomes for drug delivery and targeted therapy....
10.5281/zenodo.16993779 
Polycystic ovarian syndrome (PCOS) is one of the most prevalent endocrine conditions affecting women of reproductive age, and it is among the main causes of anovulatory i...
10.5281/zenodo.16993703 
Periodontitis represents a chronic inflammatory disorder that impacts the tooth-supporting tissues, resulting in gradual deterioration of tissue and bone structures. Loca...
10.5281/zenodo.16992664 
Cancer continues to be one of the primary causes of illness and death across the globe, with standard treatment methods often constrained by limited specificity and syste...
10.5281/zenodo.16992503 
A glucagon-like peptide-1 receptor agonist (GLP-1 RA), semaglutide, has become a key treatment for obesity and type 2 diabetes mellitus (T2DM). Significant weight reduct...
10.5281/zenodo.16991653 
Cancer remains one of the leading causes of mortality worldwide, and conventional therapeutic approaches such as chemotherapy, radiotherapy, and surgery are often limited...
10.5281/zenodo.16991284 
A simple, accurate, as well as precise Reverse Phase High-Performance Liquid Chromatography (RP-HPLC) method was developed to estimate Glimepiride in pharmaceutical dosag...
10.5281/zenodo.16991082 
The main objective of the present work is to determine a novel, stability-indicating reversed phase high performance liquid chromatography (RP-HPLC) method has been devel...
10.5281/zenodo.16980657 
The escalating prevalence of obesity and Type 2 Diabetes Mellitus posess a significant public health concern, necessitating innovative therapeutic strategies, mitigate co...
10.5281/zenodo.16980614 
Amorphophallus Paeoniifolius known as Elephant foot yam is basically a crop of Southeast Asian origin belongs to the family Araceae. In India is commonly known as "Suran"...
10.5281/zenodo.16980480 
A post-zygotic mosaic mutation in the AKT1 gene causes the uncommon, progressive, and sporadic overgrowth disorder known as Proteus syndrome. Its defining feature is asym...
10.5281/zenodo.16980399 
Materiovigilance, the science and activities relating to the detection, assessment, understanding, and prevention of adverse events associated with medical devices, has u...
10.5281/zenodo.16980254 
The pharmaceutical industry is attempting to discover thin films as a new drug delivery system and described as an alternative approach to conventional dosage forms and u...
10.5281/zenodo.16979644 
The aim of the present study was to develop, validate and compare two simple, precise and accurate UV spectrophotometric methods i.e. simultaneous equation and dual wavel...
10.5281/zenodo.16977598 
A Novel, Simple, Sensitive, and Economic Revers-phase high-performance liquid chromatography (RP-HPLC) method has been developed and validated for simultaneous estimation...
10.5281/zenodo.16976834 
The study investigates the advancements resulting from integrating Industry 4.0 technologies into oncological practices in Hyderabad. The study emphasizes the ongoing i...
10.5281/zenodo.16951820 
The present study focuses on the formulation and evaluation of a 100% herbal hair dye using natural plant-based ingredients as an alternative to synthetic chemical dyes. ...
10.5281/zenodo.16951727 
Metachromatic leukodystrophy (MLD) is a rare, inherited lysosomal storage disorder characterized by the progressive demyelination of the central and peripheral nervous sy...
10.5281/zenodo.16950440 
Guillain Barré syndrome is one of the best examples of a post infectious immune disease and offers insights into the mechanism of tissue damage in other more common auto...
10.5281/zenodo.16950380 
Tofacitinib is an oral, small molecule JAK inhibitor that targets JAK1/JAK3. Tofacitinib has been approved by the FDA to be used in the treatments of rheumatoid arthritis...
10.5281/zenodo.16949594 
Sikkim have a rich diversity of medicinal plants which is located in Eastern Himalayan regions of India, from ancient times Sikkimese’s peoples used medicinal plants in...
10.5281/zenodo.16949435 
From Since from very old times Ayurveda is always a deep ocean for many known or unknown medicinal pearls. Some of its gems are always controversial due to their morpholo...
10.5281/zenodo.16949357 
Schiff bases and their transition metal complexes have long been recognized for their pharmacological relevance, particularly as antioxidant and anticancer agents. The im...
10.5281/zenodo.16949332 
Traditional medical systems have relied heavily on medicinal plants, which also supply bioactive ingredients for contemporary drug development. The goal of this study was...
10.5281/zenodo.16949087 
Suranj?n Sh?r?n (Colchicum autumnale Linn.), commonly known as Meadow Saffron or Autumn Crocus, is a well-known medicinal plant in both Unani and modern medicine. Traditi...
10.5281/zenodo.16948927 
Katepurna Wildlife Sanctuary, located in the Vidarbha region of Maharashtra, is an ecologically critical area supporting diverse flora. This research assesses the florist...
10.5281/zenodo.16948851 
The primary goal of the current research is the creation of a novel therapeutic option for a variety of disorders such inflammation and wounds, which are more frequently ...
10.5281/zenodo.16948477 
Software as a Medical Device (SaMD) has become quite a transformative element in healthcare for the reason that it delivers diagnostic, therapeutic, also monitoring solut...
10.5281/zenodo.16948189 
Exosomes are nanosized extracellular vesicles secreted by diverse cell types, playing pivotal roles in intercellular communication, disease progression, and therapeutic i...
10.5281/zenodo.16948015 
The cholinergic system plays a central role in regulating cognition, memory, neuromuscular transmission, and autonomic functions. Dysregulation of this system is closely ...
10.5281/zenodo.16947719 
The 5-HT (serotonin) and dopamine receptor antagonist ziprasidone (CP-88,059) has strong effects in preclinical tests that predict antipsychotic effectiveness. In vitro a...
10.5281/zenodo.16947413 
Begonia roxburghii is a lesser-known but important species in the Begoniaceae family. It is native to the humid subtropical areas of South and Southeast Asia, especially ...
10.5281/zenodo.16947090 
Sterile pharmaceutical products—such as injectables, ophthalmic solutions, and implantable drugs—demand the highest standards of quality assurance (QA) due to their d...
10.5281/zenodo.16941014 
Pilocytic astrocytoma (PA) is a kind of benign brain tumor. The most prevalent age group for PA, a brain tumor grade I according to the World Health Organization, is 0...
10.5281/zenodo.16940746 
Benincasa hispida is a Traditional medicinal plant used for many purposes. The present review study is about the natural herb, Benincasa hispida also known as Ash gourd, ...
10.5281/zenodo.16940616 
The Electroconvulsiometer and Actophotometer are key experimental instruments in neuropharmacological research, widely employed for screening and evaluating the effects o...
10.5281/zenodo.16940508 
Pityriasis rubra pilaris is a rare, chronic, papulosquamous skin disorder characterized by follicular hyperkeratosis, erythematous scaling plaques, and palmoplantar kerat...
10.5281/zenodo.16940424 
Hair and scalp disorders like dandruff and candidiasis are often linked to microbial infections and poor scalp health, leading to flaking, itching, and hair damage. Conve...
10.5281/zenodo.16940167 
Tobacco is one of the major causes to the preventable worldwide deaths. Tobacco is not only major carcinogenic agent but cause to cancer and their associated problems aro...
10.5281/zenodo.16939513 
Intellectual Property Rights (IPRs) constitute a cornerstone of modern innovation systems by providing legal protection to creations of the human intellect, including inv...
10.5281/zenodo.16939173 
Nanoemulsions have attracted a lot of attention as innovative drug delivery techniques because they can increase the solubility, stability, and bioavailability of drugs t...
10.5281/zenodo.16939085 
Zinc Oxide nanoparticles refer to a white powder compound that is insoluble in water and has excellent chemical, electrical, and thermal stabilities. It is widely used in...
10.5281/zenodo.16938998 
Chalcones, a class of naturally occurring and synthetically derivable flavonoids, have shown promising pharmacological properties, including anxiolytic activity. In the p...
10.5281/zenodo.16933985 
The present study outlines the development of a highly specific and reproducible first-order derivative spectroscopic method for the quantitative estimation of Gliclazide...
10.5281/zenodo.16933910 
Drug delivery systems (DDS) have evolved significantly to improve therapeutic efficiency, stability, and patient compliance, yet challenges such as poor targeting, variab...
10.5281/zenodo.16933851 
Priapism is a rare but serious urological emergency characterized by a prolonged penile erection lasting more than four hours, unrelated to sexual arousal. Ischemic priap...
10.5281/zenodo.16933074 
The co-existence of diabetes mellitus and cardiovascular diseases presents a significant clinical challenge that demands innovative, patient-centric therapeutic solutions...
10.5281/zenodo.16932975 
Pharmacovigilance (PV), which involves the evaluation, tracking, and identification of drug interactions and their effects on humans, is essential to the healthcare syste...
10.5281/zenodo.16932824 
Schizophrenia is a disabling neuropsychiatric illness that is a chronic illness that is characterized by alterations in cognition, affect and social behaviour. Whereas st...
10.5281/zenodo.16932838 
Marine cosmeceuticals harness bioactive compounds from oceanic sources such as algae, marine animals, microorganisms, and minerals to offer innovative, natural alternativ...
10.5281/zenodo.16932756 
Herbal peel-off face masks have become increasingly popular in recent years due to their gentle nature, versatility, and suitability for almost all skin types. This revie...
10.5281/zenodo.16932679 
The present study focuses on the extraction, isolation, phytochemical screening, and analysis of Madhunashini (Gymnema Sylvestre), a medicinal plant renowned for its anti...
10.5281/zenodo.16932631 
In the present study, a series of Pyrazolidine 3, 5 Dione derivative compounds were evaluated for their molecular binding affinity using in silico docking techniques. Doc...
10.5281/zenodo.16931843 
Lopinavir is a BCS Class II drug exhibiting poor bioavailability due to P-gp efflux and limited permeation. The aim of this research was to formulate and characterize co-...
10.5281/zenodo.16931281 
Cancer remains one of the most significant global health challenges, with high mortality rates and limited treatment success for advanced stages. Since the approval of ci...
10.5281/zenodo.16931001 
A couple of new N-3-chloropropyl-benzothiazole-2-amine derivatives (Compound B1, B2) and N-benzothiazol-2-yl)-2-chloroacetamide derivatives (Compound A1, A2) were the foc...
10.5281/zenodo.16928690 
Since its inception, Green Chemistry has focused on the necessity of removing or reducing the detrimental impact that different organic solvents have on the environment a...
10.5281/zenodo.16928277 
The present research focuses on the design, synthesis, and biological evaluation of novel quinoline–azetidinone hybrid molecules with potential antioxidant activity. Re...
10.5281/zenodo.16928020 
The outbreak of the coronavirus in 2020 triggered a global emergency, leading to widespread loss of life, nationwide lockdowns, and critical medical challenges. Beyond th...
10.5281/zenodo.16927094 
Natural herbs, remedies, and procedures are generally safer than chemical products due to their fewer side effects. The ingredients, often sourced from nature and our sur...
10.5281/zenodo.16926864 
Hepatitis C virus (HCV) infection affects more than 70 million individuals globally and remains a leading cause of cirrhosis, hepatocellular carcinoma, and liver-related ...
10.5281/zenodo.16926832 
Diabetes mellitus is a long-lasting metabolic condition marked by elevated blood sugar levels, caused either by insufficient insulin production or the body's inability to...
10.5281/zenodo.16926516 
The surgical zipper skin closing device offers a non-intrusive, sterile, atraumatic, hypoallergenic, and hydrophobic approach for closing the surgical wounds. This zipper...
10.5281/zenodo.16926328 
Antibiotic resistance emerges as a major threat globally. By persistent selection pressure, bacteria gain the ability to resist the effects of an antibiotic. Large number...
10.5281/zenodo.16926231 
Post-marketing surveillance plays a pivotal role in ensuring the safety and efficacy of medicines after their approval for clinical use. In India, adverse drug reaction (...
10.5281/zenodo.16926159 
Creams have long been used as topical preparations due to their ease of application and removal from the skin. Pharmaceutical creams serve a wide range of purposes, from ...
10.5281/zenodo.16925072 
Pigmentation is a process in which the skin darkens due to increased melanin production, often resulting from prolonged exposure to ultraviolet (UV) radiation. While UV r...
10.5281/zenodo.16924938 
Developing a new drug requires a great amount of research work in chemistry, manufacturing, controls, preclinical science, and clinical trials. Drug reviewers in regulato...
10.5281/zenodo.16924714 
Chrono-therapeutics, the strategic timing of medication administration to align with the body's circadian rhythms, has emerged as a promising approach to enhance therapeu...
10.5281/zenodo.16924561 
Buccal mucoadhesive drug delivery systems offer a promising alternative to conventional oral and parenteral routes by enabling drug absorption directly through the buccal...
10.5281/zenodo.16919099 
Aegle marmelos, better known as bael, has long been celebrated in traditional medicine for its potential health benefits, especially when it comes to managing diabetes me...
10.5281/zenodo.16919067 
The evolution of drug delivery science has ushered in a new era of precision therapeutics, driven by the development of Novel Drug Delivery Systems (NDDS) that aim to ove...
10.5281/zenodo.16918800 
Despite their extensive usage, the performance of BCS Class II drugs is often hampered by the low solubility of these drugs. In order to overcome these shortcomings, nano...
10.5281/zenodo.16918694 
The aim of the current investigation was to screen several excipients for use in the development of Itopride nanoemulsion drug formulations. Nanoemulsions were prepared b...
10.5281/zenodo.16918488 
Oral drug delivery is widely used route of drug administration by wide range of populations. Various types of oral dosage forms available are tablets, capsules, solutions...
10.5281/zenodo.16917247 
Psychosis is a severe mental disorder which is characterized by disturbance in thinking and perception. It is accompanied by hallucinations and delusions. It is a disorde...
10.5281/zenodo.16917037 
The effectiveness of drugs can be enhanced by creating innovative delivery methods, including Mucoadhesive drug delivery systems (MDDS) offer a novel approach for deliver...
10.5281/zenodo.16916890 
In this study, magnesium oxide (MgO) nanoparticles were successfully synthesized using Momordica charantia fruit extract via a green chemistry approach. The formation of ...
10.5281/zenodo.16916703 
Doxycycline is a common antibiotic used in skin care, especially for treating moderate to severe acne in young adults. It is usually safe, but it can sometimes cause a pa...
10.5281/zenodo.16916630 
In the present study, a series of 1-ethyl-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-chloro-3-quinoline carboxylic acid substituted with phenyl thiourea at C-3, ethyl, cycl...
10.5281/zenodo.16910457 
Pharmacological screening is a fundamental process in drug discovery and development, involving the evaluation of drugs, herbal extracts, and chemical compounds for thera...
10.5281/zenodo.16910360 
Nanotechnology has garnered growing attention recently because of its potential to diagnose and treat numerous tumors, as nanocarriers have been used to overcome the chal...
10.5281/zenodo.16910214 
Background: Skin aging is a complex process that destroys human skin when exposed to ultraviolet (UV) irradiation on a continuous basis. Skin wrinkling eventually result...
10.5281/zenodo.16909327 
Hypertension, or high blood pressure, is a major risk factor for cardiovascular diseases, accounting for a significant burden on global healthcare systems. Despite the av...
10.5281/zenodo.16908660 
Self-nanoemulsifying drug delivery systems (SNEDDS) have emerged as a promising approach for improving the oral bioavailability of poorly water-soluble drugs, particularl...
10.5281/zenodo.16908521 
Oral insulin represents a promising alternative to subcutaneous (SC) administration for diabetes management, with potential physiological, practical, and psychosocial ben...
10.5281/zenodo.16904153 
Pharmacovigilance (PV) constitutes a fundamental pillar of global drug safety, encompassing the systematic detection, assessment, understanding, and prevention of adverse...
10.5281/zenodo.16904100 
Ovarian cancer (OC) remains the deadliest of the gynecologic malignancies, largely because more than 70?% of patients present with advanced?stage disease and quickly acqu...
10.5281/zenodo.16903990 
Medicine-related problems (MRPs) impose tremendous challenges on healthcare systems around the world, affecting patient outcomes from childhood to advanced old age. This ...
10.5281/zenodo.16903911 
3D printing advanced by the 1980s. The term "three dimension-al (3D) printing" refers to a variety of manufacturing techniques and technologies that use digital data to c...
10.5281/zenodo.16901233 
Gastroprotective drug delivery systems (GRDDS) have emerged as a promising approach to enhance the bioavailability and therapeutic efficacy of drugs with narrow absorptio...
10.5281/zenodo.16901002 
Isoquinolines (C?H?N)[1] are a broadly important class of nitrogen-containing heterocycles found in numerous natural alkaloids[21] and synthetic drug leads. Their structu...
10.5281/zenodo.16900760 
Purpose: The iris and its qualitative, quantitative and dynamic factors are closely responsible for the prevalence and severity of Primary Angle Closure Glaucoma. This is...
10.5281/zenodo.16900334 
This study presents a novel approach for the concurrent quantification of Dapagliflozin and Vildagliptin in tablet form. Chromatogram was analysed using a Discovery C18 c...
10.5281/zenodo.16895422 
A quick, exceedingly sensitive reverse phase high performance liquid chromatographic method has been developed and validated for the estimation of Safinamide in bulk drug...
10.5281/zenodo.16895066 
Three-dimensional (3D) printing is transforming the pharmaceutical industry by enabling precise, personalized drug delivery systems. This review discusses various 3D prin...
10.5281/zenodo.16894484 
Urinary tract infection are among most common bacterial infection affecting individuel worldwide The present study focuses on the formulation and evaluation of a novel fl...
10.5281/zenodo.16894425 
The objective of the present work was to develop and evaluate an oro-dental gel for targeted management of oral pain and inflammation. Ketorolac tromethamine, a potent NS...
10.5281/zenodo.16894420 
Dapagliflozin, a sodium-glucose co-transporter-2 (SGLT2) inhibitor primarily used for type 2 diabetes mellitus (T2DM), has recently emerged as a potential therapeutic opt...
10.5281/zenodo.16893377 
Human immunodeficiency virus (HIV) positive individuals are highly susceptible to extrapulmonary tuberculosis (EPTB) and other opportunistic infections due to immune supp...
10.5281/zenodo.16892073 
Many individuals—including the elderly, young children, and patients with certain medical conditions—face difficulties in swallowing conventional tablets. Fast-disint...
10.5281/zenodo.16892252 
Multi-drug resistance patterns in bacteria are difficult to treat. The search for a new alternative antibiotic drug that may help to control drug-resistant pathogenic bac...
10.5281/zenodo.16892073 
The present study focuses on the formulation and evaluation of a gastro-retentive floating controlled release tablet of Amiloride, aimed at enhancing gastric residence ti...
10.5281/zenodo.16887070 
The skin, the biggest organ in the human body, is made up of three layers: epidermis, dermis, and subcutaneous layer. Melanocytes and keratinocytes are pigment- producing...
10.5281/zenodo.16887028 
Water quality is essential for public health. Contaminants present in the water can affect the water quality and public health. This paper presents the quality assessment...
10.5281/zenodo.16887008 
This research developed and evaluated a herbal hair mask combining Moringa pulp, flaxseeds, and rice water for hair conditioning and smoothing. Flaxseeds, rich in omega-3...
10.5281/zenodo.16886496 
Background: Medicinal plants are a crucial component in traditional and modern healthcare. Curry leaves (Murraya koenigii) are prized in Asian cuisine and recognized for ...
10.5281/zenodo.16886263 
Radiopharmaceutical science has now become a pivotal way of advancing research and therapies within oncology and expanding the future of oncology itself, largely due to d...
10.5281/zenodo.16885394 
Atopic dermatitis (AD) is a long-lasting inflammatory skin disease that shows signs of itching, redness, and skin lesions, which affect the quality of life of patients to...
10.5281/zenodo.16885326 
This prospective observational study was conducted over a six-month period in a tertiary care teaching hospital to evaluate antibiotic resistance patterns and review anti...
10.5281/zenodo.16885273 
The drug delivery systems which respond to the stimuli are the most advanced systems, helps in diagnosing the diseases and treating them. Different types of stimuli have ...
10.5281/zenodo.16885205 
The purpose of the present research was to formulate and evaluate an anti-aging herbal cream. Most existing creams are prepared using synthetic drugs, which often cause s...
10.5281/zenodo.16883578 
Gastroesophageal reflux disease is a prevalent global condition associated with increasing prevalence rates. Effective management involves lifestyle modifications and pha...
10.5281/zenodo.16882865 
DNA fingerprinting techniques have become essential tools in the identification, authentication, and quality control of drugs of natural origin, especially herbal medicin...
10.5281/zenodo.16882759 
Cocrystals are defined as multicomponent crystalline materials composed of an active pharmaceutical ingredient (API) and one or more neutral coformers, held together thro...
10.5281/zenodo.16882709 
Medication adherence is a critical determinant of clinical outcomes across healthcare delivery models. In both dispensing and non-dispensing practices, pharmacists and ot...
10.5281/zenodo.16881444 
Drug reprofiling, also referred to as drug repurposing or repositioning, finds new therapeutic applications for drugs that are already on the market or have already faile...
10.5281/zenodo.16881340 
Over the past decades, gel-based system has been gained greater attention as an innovative approach in drug delivery, particularly for developing regulated and sustained ...
10.5281/zenodo.16881045 
Background: Echinacea purpurea (L.) Moench, commonly known as purple coneflower, has been traditionally employed in North American and European herbal medicine for its im...
10.5281/zenodo.16880875 
Thiazolidinedione plays an important role in activation of PPAR-? receptors and help to prevent insulin resistance diabetes by binding to DNA by the formation of complexe...
10.5281/zenodo.16880395 
A novel, sensitive, and robust High-Performance Liquid Chromatography (HPLC) method was developed and validated for the simultaneous estimation of Fluticasone furoate and...
10.5281/zenodo.16880135 
Stem cell therapy has emerged as a promising approach for the treatment of ovarian failure and testicular dysfunction, two major contributors to infertility and endocrine...
10.5281/zenodo.16877793 
Fast disintegrating tablets (FDTs) have revolutionized oral drug delivery by offering rapid disintegration and dissolution in the oral cavity without the need for water, ...
10.5281/zenodo.16876932 
Stress and burnout are increasingly recognized as significant issues affecting resident physicians, impacting their performance, mental health, and patient care. This stu...
10.5281/zenodo.16875472 
Genotoxic impurities (GTIs) in pharmaceutical formulations raise critical concerns due to their potential to cause genetic mutations and possibly lead to cancer. While co...
10.5281/zenodo.16875313 
Chronic wounds, such as diabetic foot ulcers, pressure sores, and venous leg ulcers, represent a significant global healthcare burden due to their prolonged healing times...
10.5281/zenodo.16875202 
The emerging issues of species specificity and sensitivity analysis cannot be satisfactorily resolved using conventional analysis technique such as high-performance liqui...
10.5281/zenodo.16875161 
Quinidine, an alkaloid found naturally in cinchona, has been used extensively in cardiology for more than a century. Since its first isolation as a stereoisomer of quinin...
10.5281/zenodo.16875088 
The emergence of stimuli-responsive drug delivery systems (SRDDS), often referred to as smart drug delivery platforms, represents a transformative leap in the field of ph...
10.5281/zenodo.16872500 
Diabetic nephropathy (DN), a significant microvascular complication of diabetes mellitus, is a major cause of end-stage renal disease globally. Chronic hyperglycemia, re...
10.5281/zenodo.16872206 
The transdermal route is increasingly recognized as a valuable alternative to oral drug delivery, particularly for addressing limitations such as first-pass metabolism an...
10.5281/zenodo.16870854 
The concept of ‘Herbal medicine’ has its origins in ancient societies. In these medicines we use that are plants or its parts to cure disease and improve health and w...
10.5281/zenodo.16870393 
Background: Hemorrhoids are a common anorectal condition characterized by inflammation, pain, and bleeding. Conventional treatments often carry side effects, prompting in...
10.5281/zenodo.16870047 
Pharmaceutical drug analysis plays a vital role in the discovery, design, development, and manufacturing of pharmaceutical products. It ensures the identity, purity, qual...
10.5281/zenodo.16869624 
Bioelectronic medicine (BEM) is an interdisciplinary field integrating neuroscience, bioengineering, and clinical medicine to diagnose and treat disease through targeted ...
10.5281/zenodo.16869157 
Fungal infections remain a major health concern due to increasing resistance against existing antifungal agents. In this review, novel 1,2,4-triazole derivatives were syn...
10.5281/zenodo.16856764 
Design and Synthesis of Benzotriazole Derivatives for Anticonvulsant Activity Epilepsy is a prevalent neurological disorder significantly impacting global health and econ...
10.5281/zenodo.16854335 
Oral dosage forms are the most common route of drug administration despite has several disadvantages such as poor patient compliance, slow absorption etc. However, in liq...
10.5281/zenodo.16852535 
This study presents the rational design and in silico evaluation of novel isoniazid-linked 5,1H-tetrazole derivatives as potential inhibitors of Mycobacterium tuberculosi...
10.5281/zenodo.16851870 
Transdermal drug delivery techniques may avoid gastrointestinal breakdown and hepatic first-pass metabolism, they have become a viable substitute for conventional methods...
10.5281/zenodo.16851658 
One important feature of pharmaceutical goods that has a direct bearing on their safety, effectiveness, and shelf life is stability. The need for reliable, validated anal...
10.5281/zenodo.16849573 
Effective drug delivery at a targeted site had given the possibility to perform the precise function to control the release rates and have a better compliance on the heal...
10.5281/zenodo.16849056 
The present study was aimed at the development and evaluation of an in situ nasal gel formulation of Montelukast Sodium Six formulations (F1–F6) of Montelukast Sodium i...
10.5281/zenodo.16848374 
Attempts were made to develop an RP-HPLC method for the simultaneous estimation of Carvedilol & Ivabradine from Tablet. For the RP Agilent Tech. Gradient System with...
10.5281/zenodo.16830344 
Green chemistry principles advocate for the development of more sustainable synthetic methods by enhancing efficiency, minimizing toxic solvent usage, reducing reaction s...
10.5281/zenodo.16814528 
Over-the-counter (OTC) medications are widely used for the relief of minor, self-limiting ailments such as headaches, colds, fever, allergic reactions, and digestive disc...
10.5281/zenodo.16814490 
Carnisure represents a critical therapeutic intervention for disorders of fatty acid metabolism and energy production. As a bio available form of L-carnitine, it serves a...
10.5281/zenodo.16814420 
In the pharmaceutical industry, drug recalls are critical events that can significantly impact public health, company reputation, and financial stability. This study inve...
10.5281/zenodo.16812751 
Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causi...
10.5281/zenodo.16812571 
Global developmental delay (GDD) has a significant impact on affected children, families and society. The present study was aimed to finding the prevalence and risk facto...
10.5281/zenodo.16812108 
Fimasartan potassium trihydrate was quantitatively calculated in tablet and bulk dose forms utilizing the straightforward, accurate, and economical high-performance thin-...
10.5281/zenodo.16811829 
The Indian mining industry, a critical pillar of the nation's economy, faces persistent challenges, including operational inefficiencies, environmental degradation, secur...
10.5281/zenodo.16811494 
Film forming gels have emerged as an innovative and novel drug delivery system that offers controlled and prolonged drug release. These formulations form thin, flexible a...
10.5281/zenodo.16811197 
The ongoing COVID- 19 epidemic has stressed the critical need for rapid-fire, accurate, and scalable individual styles. Rear recap circle- intermediated isothermal modifi...
10.5281/zenodo.16810823 
Herbal treatments are safe and efficient for treating a wide range of ailments. Western medicine, or allopathy, is primarily reliant on medicinal plants for some of its c...
10.5281/zenodo.16810487 
The gut microbiota plays a pivotal role in the bidirectional communication network between the gastrointestinal tract and the central nervous system, collectively termed ...
10.5281/zenodo.16810273 
Thiazolidinediones (TZDs) are a well-known class of antidiabetic agents predominantly recognized for their action as peroxisome proliferator-activated receptor gamma (PPA...
10.5281/zenodo.16810059 
The abstract of a study on the photochemical and pharmacogenetic properties of hibiscus would summaries the research conducted on the plant and its active chemical compou...
10.5281/zenodo.16809877 
A chronic, progressive neurodegenerative illness, Parkinson's disease (PD) is characterized by the destruction of dopaminergic neurons in the substantia nigra pars compac...
10.5281/zenodo.16801148 
Alzheimer’s disease (AD), long defined by amyloid-beta plaques and neurofibrillary tangles, is increasingly recognized as a metabolic disorder, with insulin resistance ...
10.5281/zenodo.16799942 
Green Analytical Chemistry (GAC) represents a transformative paradigm in chemical analysis, dedicated to minimising the environmental footprint and health risks associate...
10.5281/zenodo.16799280 
The present study focuses on the formulation and evaluation of sustained release pellets of Rabeprazole Sodium using the extrusion-spheronization technique. Rabeprazole, ...
10.5281/zenodo.16798605 
The primary cause of dementia, Alzheimer's disease (AD) is a progressive neurological illness marked by behavioral abnormalities, memory loss, and cognitive decline. Amyl...
10.5281/zenodo.16795722 
The main purpose of this work is to formulate and evaluate a cosmetic herbal face pack for having the glowing skin by using Panchgavyas. It mainly contains cow dung,curd ...
10.5281/zenodo.16795729 
Curcumin, the bioactive compound with strong antibacterial properties presents in turmeric faces challenges in clinical applications due to its poor solubility, instabili...
10.5281/zenodo.16795628 
Since herbal medications have become more and more popular worldwide, it is now essential to carefully monitor their quality in order to ensure both their effectiveness a...
10.5281/zenodo.16795548 
Messenger RNA (mRNA)- based therapeutics have revolutionized the landscape of pharmacology, especially following their success in COVID-19 vaccine development. This revie...
10.5281/zenodo.16795475 
This review presents a relative analysis of traditional insulin remedy and Lantidra, a new remedial approach for managing diabetes mellitus. In order to give sapience i...
10.5281/zenodo.16794883 
Barlow’s disease is a primary form of mitral valve prolapse (MVP) characterized by myxomatous degeneration, leading to excessive leaflet thickening, redundancy, and elo...
10.5281/zenodo.16794763 
BMIs or value BCIs are the devices still in progress which create a couple connection of the outer workings of a device with a human body and brain for the purposes of a ...
10.5281/zenodo.16794166 
Hyperlipidemia is a prevalent metabolic disorder characterized by elevated levels of plasma lipids, including cholesterol, triglycerides, and various lipoproteins such as...
10.5281/zenodo.16793885 
Decompensated Chronic Liver Disease (DCLD) signifies the advanced stage of cirrhosis, characterized by the emergence of critical complications such as ascites, hepatic en...
10.5281/zenodo.16793526 
Ayurveda, the ancient science of life, lays strong emphasis on the preservation of health through the principle of "Swasthasya Swasthya Raksanam"—maintaining the health...
10.5281/zenodo.16793277 
Acid-base indicators play a crucial role in chemical analysis, industry, and everyday applications. These substances change color in response to pH variations, making the...
10.5281/zenodo.16793133 
A straightforward, rapid, sensitive, precise, and specific UV spectrophotometric method was developed and validated for the determination of Fimasartan Potassium Trihydra...
10.5281/zenodo.16792605 
The present study described a new, simple, accurate and precise development for estimation of selexipag by RP Agilent Tech. Gradient System with Auto injector, UV (DAD)...
10.5281/zenodo.16792379 
Jasminum officinale L. (Oleaceae), commonly known as common jasmine, has been traditionally employed in multiple medicinal systems. This study comprehensively evaluates i...
10.5281/zenodo.16789644 
Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by symmetric joint inflammation, leading to joint pain, swelling, and eventually joint damage and ...
10.5281/zenodo.16789568 
The potential of cannabis to treat medical problems has drawn more attention. The adverse effects of exposure can be unpredictable because to the variety of cannabis-base...
10.5281/zenodo.16789488 
Oral squamous cell carcinoma (OSCC) is one of the most deadly diseases in the head and neck region, accounting for one-third of all head and neck cancer deaths. Mortality...
10.5281/zenodo.16789450 
Microspheres are free flowing powders having particle size in the range of 1-1000µm with biologically active drugs intended for providing constant and prolonged therapeu...
10.5281/zenodo.16789393 
The plant Erythrina variegata is traditional medicinal plant. Different parts of Erythrina variegata have used in traditional medicine as nervine sedative, febrifuge, ant...
10.5281/zenodo.16789320 
Multiple Myeloma (MM) is a hematological malignancy marked by the proliferation of abnormal plasma cells in the bone marrow, leading to multiple systemic complications in...
10.5281/zenodo.16789251 
Pharmacovigilance (PV), also referred to as drug safety, encompasses the science and activities involved in detecting, assessing, understanding, and preventing adverse dr...
10.5281/zenodo.16789208 
Most of the pharmaceuticals are analyzed using UV-Visible methods due to their simplicity, better understanding for students, and economy. Ammonia and primary amino group...
10.5281/zenodo.16789120 
Pogostemon parviflorus Benth (Lamiaceae), Houttuynia cordata Thunb (Saururaceae) and Solanum spirale Roxb (Solanacea) are traditionally used as vegetables to cure stomach...
10.5281/zenodo.16778663 
The blue-green algae (Cyanoprokaryotes) are considered as one of the most ancient microorganisms. The members of this group are capable to perform oxygenic photosynthesis...
10.5281/zenodo.16778619 
India has one of the world's highest diabetes burdens. As of 2024, an estimated 89.8 million individuals (20-79 years old) in India have diabetes, with the figure expect...
10.5281/zenodo.16778584 
Diuretics are mainly used in the management of hypertension, chronic kidney disease (CKD), heart failure, and numerous hypervolemic disorders. Different diuretics work on...
10.5281/zenodo.16778496 
Acne vulgaris is a common dermatological condition affecting individuals of all age groups, especially adolescents. Conventional therapies often cause side effects like d...
10.5281/zenodo.16778414 
A new and improved pharmaceutical dosage form called a bilayer tablet was created to get around some of the drawbacks of traditional single-layer tablets. Because of thei...
10.5281/zenodo.16777525 
Hypertension affects over 1.13 billion people worldwide and remains a leading risk factor for cardiovascular disease, stroke, and kidney disease. While conventional antih...
10.5281/zenodo.16777401 
Levulinic acid (LA) is a bio-based platform chemical with wide-ranging applications in food, fuel, and pharmaceuticals. Its derivatives—such as sodium, calcium, methyl,...
10.5281/zenodo.16777357 
Objectives: This study aimed to study the in-vitro studies on antidiabetic and antioxidant activity of Hydroalcoholic extract of Barleria prionitis linn. The objectives i...
10.5281/zenodo.16777301 
Printing technology is a rising innovation with the quickest beginning in the oral thin film manufacturing techniques. While the printing technology already enables a pre...
10.5281/zenodo.16760922 
The present investigation was aimed to determine the “Study on Marketing of Medicinal Plants (Insulin Plant) [6] This plant mostly known as a decorative plant in India,...
10.5281/zenodo.16760796 
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that presents with a variety of clinical symptoms and unpredictable flare-ups. Hydroxychloroquine (HCQ)...
10.5281/zenodo.16760739 
This review focus on polyherbal extract having Anti-inflammatory activity. This consists essential oil of poly-herb such as turmeric, peppermint, ginger. Turmeric is a rh...
10.5281/zenodo.16760698 
The recent past in the technological development evidenced that evolution in Nanotechnology and nanoscience is the key factor. Nanotechnology is multidisciplinary science...
10.5281/zenodo.16759604 
Diabetes mellitus is a major global health concern, affecting millions of people. Existing treatments, including as insulin injections and oral medicines, assist manage ...
10.5281/zenodo.16759225 
Norovirus is a highly contagious, non-enveloped RNA virus that is recognized as the leading cause of acute gastroenteritis across all age groups globally. It belongs to t...
10.5281/zenodo.16758790 
Langya henipavirus (Lay V) is an emerging zoonotic pathogen belonging to the Henipavirus genus, closely related to the highly pathogenic Nipah and Hendra viruses. First d...
10.5281/zenodo.16758675 
Veliparuthi (Pergularia daemia) (Family: Apocynaceae) is also known as uthamani in Tamil, utaran in Hindi, and trellis-0vine in English. It is medicinal plant with variou...
10.5281/zenodo.16758069 
3Products known as nutraceuticals are utilized as medicines in addition to being used for nourishment. A substance that has physiological benefit3s or offers protection a...
10.5281/zenodo.16757985 
The main objective of this study was to formulate and evaluate the oral dispersible tablets of amlodipine besylate with natural and synthetic super disintegrants. Various...
10.5281/zenodo.16750294 
The practice of self-medication, especially among college students, is increasingly recognized as a significant public health issue globally. It involves individuals inde...
10.5281/zenodo.16755101 
By improving diagnostic accuracy , expediting treatment planning and facilitating data-driven clinical decision making ,Artificial Intelligence (AI) is transforming the H...
10.5281/zenodo.16753475 
Chandipura virus (CHPV), a member of the Rhabdoviridae family and Vesiculovirus genus, is an emerging neurotropic virus identified primarily in India. It causes acute enc...
10.5281/zenodo.16753331 
Herbal formulations have long been integral to traditional medical practices and are increasingly acknowledged in modern healthcare for their natural origins and therapeu...
10.5281/zenodo.16753139 
Herbal Medicine sometimes referred to as Herbalism or Botanical Medicine, is the use of herbs for their therapeutic or medicinal value. The herb is a plant or plant part ...
10.5281/zenodo.16753078 
The poor aqueous solubility of many newly developed drugs, particularly those categorized as Biopharmaceutics Classification System (BCS) Class II, limits their o...
10.5281/zenodo.16751734 
Itraconazole (ITZ), a poorly water-soluble antifungal drug, exhibits limited oral bioavailability, which hampers its therapeutic efficacy. This study aimed to develop a n...
10.5281/zenodo.16751633 
Ocular drug delivery is a complex and challenging area due to various anatomical and physiological barriers that limit drug penetration and retention. Conventional eye dr...
10.5281/zenodo.16750877 
Punarnava is the ancient medicinal plant belongs to the Nyctaginaceae family. It is available in three different species B.diffusa, B.verticillata, T.portulaca there root...
10.5281/zenodo.16750613 
This review delves into the intricate pharmacodynamics of polysaccharides in the realm of cancer therapy. Polysaccharides, long regarded for their multifaceted biological...
10.5281/zenodo.16750480 
Green tea is known for its strong antioxidant and health-promoting properties. This review focuses on the compounds in green tea—mainly catechins and polyphenols—that...
10.5281/zenodo.16750391 
Acrylamide, a potentially harmful compound, is formed in starchy foods during high-temperature cooking processes such as baking, frying, and roasting through the Maillard...
10.5281/zenodo.16750294 
Mouth dissolving films (MDFs), also known as oral thin films (OTFs), have emerged as a novel and innovative drug delivery system designed to enhance patient compliance, p...
10.5281/zenodo.16747584 
Curcumin is a hydrophobic component that shows anti-cancer, antioxidant properties but it faces problem for its bioavailability. To overcome this problem Curcumin is enca...
10.5281/zenodo.16746520 
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycaemia resulting from impaired insulin secretion, insulin action, or both. The two p...
10.5281/zenodo.16746568 
Antibiotics have been a cornerstone of modern medicine since their discovery, transforming the treatment of bacterial infections and significantly reducing mortality and ...
10.5281/zenodo.16745995 
In HPLC method, Methanol and Water (75:25 % v/v) was used as mobile phase, at a flow rate of 1.0 ml/min, on HPLC system containing UV- detector with Openlab EZchrome soft...
10.5281/zenodo.16744970 
Zika virus (ZIKV), a mosquito-borne flavivirus, has emerged as a significant global health threat following widespread outbreaks in Americas and Pacific regions. Initiall...
10.5281/zenodo.16744877 
Cubosomes, which are self-assembled nanostructures derived from amphiphilic lipids in the presence of stabilizing agents, represent a significant advancement in the field...
10.5281/zenodo.16744768 
The accurate estimation of active pharmaceutical ingredients (APIs) is essential in ensuring the safety, efficacy, and quality of pharmaceutical products. This review pre...
10.5281/zenodo.16744633 
Oral disintegrating films (ODFs) have emerged as a novel and versatile platform in drug delivery, offering an effective alternative to conventional dosage forms, especial...
10.5281/zenodo.16738009 
This study investigates the anticancer potential of three newly designed compound (1a, 1b, and 1c) using molecular docking and in silico ADMET profiling. All compounds de...
10.5281/zenodo.16738011 
The present study focuses on the formulation and evaluation of mucoadhesive buccal tablets of Repaglinide using Carbopol 934P and HPMC K4M as primary polymers to enhance ...
10.5281/zenodo.16737888 
Allopathic medicine, the mainstream system of healthcare, relies extensively on scientifically developed formulations to ensure the safe, effective, and targeted delivery...
10.5281/zenodo.16737800 
The prevalence of cancer around the world emphasises how urgently novel treatments are needed. Because of their wide range of pharmacological characteristics, A class of ...
10.5281/zenodo.16737654 
This review provides a comprehensive and up-to-date exploration of indole and its derivatives, focusing on their evolving role in medicinal chemistry. Indole, a privilege...
10.5281/zenodo.16737603 
One of the most important and complex phases of drug development is lead optimization (LO), which turns early "hit" molecules into promising therapeutic candidates. The g...
10.5281/zenodo.16737592 
The development of herbal medicines has long been grounded in traditional healing systems. However, recent technological innovations are significantly transforming this f...
10.5281/zenodo.16737498 
Emulgels represent the next big step in topical drug delivery by combining the benefits of emulsions and gels with a view to enhancing the therapeutic efficacy of hydroph...
10.5281/zenodo.16737254 
Drugs that are poorly soluble in water can have their oral bioavailability and solubility increased with the use of amorphous solid dispersions (ASDs). Numerous technique...
10.5281/zenodo.16737062 
To evaluate the anti-asthmatic activity of Euphorbia hirta through pharmacological assessment and phytochemical screening. The research focuses on identifying bioactive c...
10.5281/zenodo.16735602 
Hyperacidity, commonly referred to as acid reflux, is a gastrointestinal condition caused by excessive hydrochloric acid production in the stomach. This condition can lea...
10.5281/zenodo.16724487 
Central nervous system (CNS) disorders represent a major global health burden necessitating precise and reliable quantification of CNS-active pharmaceutical ingre...
10.5281/zenodo.16724305 
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Its...
10.5281/zenodo.16724111 
Satureja hortensis L., commonly known as summer savory, is a widely used aromatic and medicinal plant belonging to the Lamiaceae family. Traditionally utilized in folk me...
10.5281/zenodo.16723871 
This review critically assesses various strategies for the isolation of bioactive from dandelion (Taraxacum officinale), which covers both traditional methods such as mac...
10.5281/zenodo.16723644 
The present study focuses on the formulation and evaluation of a herbal face wash gel using natural ingredients known for their skincare benefits. The main objective was ...
10.5281/zenodo.16723429 
The key component of a medication's efficacy, regardless of the administration mode, is its solubility. Numerouslatelyindustrializedmedicinesremain poorly bioavailable ow...
10.5281/zenodo.16723390 
CRISPR- Cas systems are a new game-changer in genetic engineering conceptually, as a technique that has much improved speed, specificity, and ease of use for editing gene...
10.5281/zenodo.16722617 
Developing a novel topical Smilax China microemulsion drug delivery system was the aim of the project. In order to identify the essential components that will be used in ...
10.5281/zenodo.16719842 
The crude solvents, varying degree of polarity solvents were used to extract Uraria picta. This study used the procedures of a potential antioxidant including DPPH study ...
10.5281/zenodo.16718004 
Background: Mefenamic acid (MA), a BCS Class II drug, exhibits poor aqueous solubility and an intensely bitter taste, which limit its oral bioavailability and patient com...
10.5281/zenodo.16717384 
Diabetes mellitus is a chronic metabolic disorder with a rapidly increasing global prevalence, leading to severe microvascular and macrovascular complications. The manage...
10.5281/zenodo.16680753 
Microalgae carry out photosynthesis very efficiently, turning 8 to 10% of solar energy into biomass. They have ways to concentrate CO?, which helps them outperform land-b...
10.5281/zenodo.16680179 
Bougainvillea glabra belonging to Nyctaginaceae family includes the widely grown ornamental plant, which is becoming more well-known for its many therapeutic uses. Flavon...
10.5281/zenodo.16679848 
Herbal medicines have been used since many centuries. In the search for new therapeutic options, novel bio-molecules of natural sources are to be investigated. Purpose of...
10.5281/zenodo.16679634 
Chronic postoperative pain (CPOP) is a common and serious problem for many patients after surgery. Even with pain relievers and various pain management plans, many still ...
10.5281/zenodo.16673760 
Hibiscus hispidissimus Griffith belonging to the family, Malvaceae is a traditionally valued but little-studied medicinal plant with substantial pharmacological potential...
10.5281/zenodo.16672312 
Calvarial abnormalities compromise neurological protection and cranial integrity. These cranial abnormalities are defined by the partial or whole absence of cranial vault...
10.5281/zenodo.16671138 
Oxadiazole derivatives have emerged as a vital class of heterocyclic compounds in medicinal chemistry due to their diverse pharmacological activities and favorable drug-l...
10.5281/zenodo.16669728 
