Highlights of Vol 3 | Issue 8 | 2025
Oral insulin represents a promising alternative to subcutaneous (SC) administration for diabetes management, with potential physiological, practical, and psychosocial ben...
Pharmacovigilance (PV) constitutes a fundamental pillar of global drug safety, encompassing the systematic detection, assessment, understanding, and prevention of adverse...
Ovarian cancer (OC) remains the deadliest of the gynecologic malignancies, largely because more than 70?% of patients present with advanced?stage disease and quickly acqu...
Medicine-related problems (MRPs) impose tremendous challenges on healthcare systems around the world, affecting patient outcomes from childhood to advanced old age. This ...
3D printing advanced by the 1980s. The term "three dimension-al (3D) printing" refers to a variety of manufacturing techniques and technologies that use digital data to c...
Gastroprotective drug delivery systems (GRDDS) have emerged as a promising approach to enhance the bioavailability and therapeutic efficacy of drugs with narrow absorptio...
Isoquinolines (C?H?N)[1] are a broadly important class of nitrogen-containing heterocycles found in numerous natural alkaloids[21] and synthetic drug leads. Their structu...
Purpose: The iris and its qualitative, quantitative and dynamic factors are closely responsible for the prevalence and severity of Primary Angle Closure Glaucoma. This is...
This study presents a novel approach for the concurrent quantification of Dapagliflozin and Vildagliptin in tablet form. Chromatogram was analysed using a Discovery C18 c...
A quick, exceedingly sensitive reverse phase high performance liquid chromatographic method has been developed and validated for the estimation of Safinamide in bulk drug...
Three-dimensional (3D) printing is transforming the pharmaceutical industry by enabling precise, personalized drug delivery systems. This review discusses various 3D prin...
Urinary tract infection are among most common bacterial infection affecting individuel worldwide The present study focuses on the formulation and evaluation of a novel fl...
The objective of the present work was to develop and evaluate an oro-dental gel for targeted management of oral pain and inflammation. Ketorolac tromethamine, a potent NS...
Dapagliflozin, a sodium-glucose co-transporter-2 (SGLT2) inhibitor primarily used for type 2 diabetes mellitus (T2DM), has recently emerged as a potential therapeutic opt...
Human immunodeficiency virus (HIV) positive individuals are highly susceptible to extrapulmonary tuberculosis (EPTB) and other opportunistic infections due to immune supp...
Many individuals—including the elderly, young children, and patients with certain medical conditions—face difficulties in swallowing conventional tablets. Fast-disint...
Multi-drug resistance patterns in bacteria are difficult to treat. The search for a new alternative antibiotic drug that may help to control drug-resistant pathogenic bac...
The present study focuses on the formulation and evaluation of a gastro-retentive floating controlled release tablet of Amiloride, aimed at enhancing gastric residence ti...
The skin, the biggest organ in the human body, is made up of three layers: epidermis, dermis, and subcutaneous layer. Melanocytes and keratinocytes are pigment- producing...
Water quality is essential for public health. Contaminants present in the water can affect the water quality and public health. This paper presents the quality assessment...
This research developed and evaluated a herbal hair mask combining Moringa pulp, flaxseeds, and rice water for hair conditioning and smoothing. Flaxseeds, rich in omega-3...
Background: Medicinal plants are a crucial component in traditional and modern healthcare. Curry leaves (Murraya koenigii) are prized in Asian cuisine and recognized for ...
Radiopharmaceutical science has now become a pivotal way of advancing research and therapies within oncology and expanding the future of oncology itself, largely due to d...
Atopic dermatitis (AD) is a long-lasting inflammatory skin disease that shows signs of itching, redness, and skin lesions, which affect the quality of life of patients to...
This prospective observational study was conducted over a six-month period in a tertiary care teaching hospital to evaluate antibiotic resistance patterns and review anti...
The drug delivery systems which respond to the stimuli are the most advanced systems, helps in diagnosing the diseases and treating them. Different types of stimuli have ...
The purpose of the present research was to formulate and evaluate an anti-aging herbal cream. Most existing creams are prepared using synthetic drugs, which often cause s...
Gastroesophageal reflux disease is a prevalent global condition associated with increasing prevalence rates. Effective management involves lifestyle modifications and pha...
DNA fingerprinting techniques have become essential tools in the identification, authentication, and quality control of drugs of natural origin, especially herbal medicin...
Cocrystals are defined as multicomponent crystalline materials composed of an active pharmaceutical ingredient (API) and one or more neutral coformers, held together thro...
Medication adherence is a critical determinant of clinical outcomes across healthcare delivery models. In both dispensing and non-dispensing practices, pharmacists and ot...
Drug reprofiling, also referred to as drug repurposing or repositioning, finds new therapeutic applications for drugs that are already on the market or have already faile...
Over the past decades, gel-based system has been gained greater attention as an innovative approach in drug delivery, particularly for developing regulated and sustained ...
Background: Echinacea purpurea (L.) Moench, commonly known as purple coneflower, has been traditionally employed in North American and European herbal medicine for its im...
Thiazolidinedione plays an important role in activation of PPAR-? receptors and help to prevent insulin resistance diabetes by binding to DNA by the formation of complexe...
A novel, sensitive, and robust High-Performance Liquid Chromatography (HPLC) method was developed and validated for the simultaneous estimation of Fluticasone furoate and...
Stem cell therapy has emerged as a promising approach for the treatment of ovarian failure and testicular dysfunction, two major contributors to infertility and endocrine...
Fast disintegrating tablets (FDTs) have revolutionized oral drug delivery by offering rapid disintegration and dissolution in the oral cavity without the need for water, ...
Stress and burnout are increasingly recognized as significant issues affecting resident physicians, impacting their performance, mental health, and patient care. This stu...
Genotoxic impurities (GTIs) in pharmaceutical formulations raise critical concerns due to their potential to cause genetic mutations and possibly lead to cancer. While co...
Chronic wounds, such as diabetic foot ulcers, pressure sores, and venous leg ulcers, represent a significant global healthcare burden due to their prolonged healing times...
The emerging issues of species specificity and sensitivity analysis cannot be satisfactorily resolved using conventional analysis technique such as high-performance liqui...
Quinidine, an alkaloid found naturally in cinchona, has been used extensively in cardiology for more than a century. Since its first isolation as a stereoisomer of quinin...
The emergence of stimuli-responsive drug delivery systems (SRDDS), often referred to as smart drug delivery platforms, represents a transformative leap in the field of ph...
Diabetic nephropathy (DN), a significant microvascular complication of diabetes mellitus, is a major cause of end-stage renal disease globally. Chronic hyperglycemia, re...
The transdermal route is increasingly recognized as a valuable alternative to oral drug delivery, particularly for addressing limitations such as first-pass metabolism an...
The concept of ‘Herbal medicine’ has its origins in ancient societies. In these medicines we use that are plants or its parts to cure disease and improve health and w...
Background: Hemorrhoids are a common anorectal condition characterized by inflammation, pain, and bleeding. Conventional treatments often carry side effects, prompting in...
Pharmaceutical drug analysis plays a vital role in the discovery, design, development, and manufacturing of pharmaceutical products. It ensures the identity, purity, qual...
Bioelectronic medicine (BEM) is an interdisciplinary field integrating neuroscience, bioengineering, and clinical medicine to diagnose and treat disease through targeted ...
Fungal infections remain a major health concern due to increasing resistance against existing antifungal agents. In this review, novel 1,2,4-triazole derivatives were syn...
Design and Synthesis of Benzotriazole Derivatives for Anticonvulsant Activity Epilepsy is a prevalent neurological disorder significantly impacting global health and econ...
Oral dosage forms are the most common route of drug administration despite has several disadvantages such as poor patient compliance, slow absorption etc. However, in liq...
This study presents the rational design and in silico evaluation of novel isoniazid-linked 5,1H-tetrazole derivatives as potential inhibitors of Mycobacterium tuberculosi...
Transdermal drug delivery techniques may avoid gastrointestinal breakdown and hepatic first-pass metabolism, they have become a viable substitute for conventional methods...
One important feature of pharmaceutical goods that has a direct bearing on their safety, effectiveness, and shelf life is stability. The need for reliable, validated anal...
Effective drug delivery at a targeted site had given the possibility to perform the precise function to control the release rates and have a better compliance on the heal...
The present study was aimed at the development and evaluation of an in situ nasal gel formulation of Montelukast Sodium Six formulations (F1–F6) of Montelukast Sodium i...
Attempts were made to develop an RP-HPLC method for the simultaneous estimation of Carvedilol & Ivabradine from Tablet. For the RP Agilent Tech. Gradient System with...
Green chemistry principles advocate for the development of more sustainable synthetic methods by enhancing efficiency, minimizing toxic solvent usage, reducing reaction s...
Over-the-counter (OTC) medications are widely used for the relief of minor, self-limiting ailments such as headaches, colds, fever, allergic reactions, and digestive disc...
Carnisure represents a critical therapeutic intervention for disorders of fatty acid metabolism and energy production. As a bio available form of L-carnitine, it serves a...
In the pharmaceutical industry, drug recalls are critical events that can significantly impact public health, company reputation, and financial stability. This study inve...
Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causi...
Global developmental delay (GDD) has a significant impact on affected children, families and society. The present study was aimed to finding the prevalence and risk facto...
Fimasartan potassium trihydrate was quantitatively calculated in tablet and bulk dose forms utilizing the straightforward, accurate, and economical high-performance thin-...
The Indian mining industry, a critical pillar of the nation's economy, faces persistent challenges, including operational inefficiencies, environmental degradation, secur...
Film forming gels have emerged as an innovative and novel drug delivery system that offers controlled and prolonged drug release. These formulations form thin, flexible a...
The ongoing COVID- 19 epidemic has stressed the critical need for rapid-fire, accurate, and scalable individual styles. Rear recap circle- intermediated isothermal modifi...
Herbal treatments are safe and efficient for treating a wide range of ailments. Western medicine, or allopathy, is primarily reliant on medicinal plants for some of its c...
The gut microbiota plays a pivotal role in the bidirectional communication network between the gastrointestinal tract and the central nervous system, collectively termed ...
Thiazolidinediones (TZDs) are a well-known class of antidiabetic agents predominantly recognized for their action as peroxisome proliferator-activated receptor gamma (PPA...
The abstract of a study on the photochemical and pharmacogenetic properties of hibiscus would summaries the research conducted on the plant and its active chemical compou...
A chronic, progressive neurodegenerative illness, Parkinson's disease (PD) is characterized by the destruction of dopaminergic neurons in the substantia nigra pars compac...
Alzheimer’s disease (AD), long defined by amyloid-beta plaques and neurofibrillary tangles, is increasingly recognized as a metabolic disorder, with insulin resistance ...
Green Analytical Chemistry (GAC) represents a transformative paradigm in chemical analysis, dedicated to minimising the environmental footprint and health risks associate...
The present study focuses on the formulation and evaluation of sustained release pellets of Rabeprazole Sodium using the extrusion-spheronization technique. Rabeprazole, ...
The primary cause of dementia, Alzheimer's disease (AD) is a progressive neurological illness marked by behavioral abnormalities, memory loss, and cognitive decline. Amyl...
The main purpose of this work is to formulate and evaluate a cosmetic herbal face pack for having the glowing skin by using Panchgavyas. It mainly contains cow dung,curd ...
Curcumin, the bioactive compound with strong antibacterial properties presents in turmeric faces challenges in clinical applications due to its poor solubility, instabili...
Since herbal medications have become more and more popular worldwide, it is now essential to carefully monitor their quality in order to ensure both their effectiveness a...
Messenger RNA (mRNA)- based therapeutics have revolutionized the landscape of pharmacology, especially following their success in COVID-19 vaccine development. This revie...
This review presents a relative analysis of traditional insulin remedy and Lantidra, a new remedial approach for managing diabetes mellitus. In order to give sapience i...
Barlow’s disease is a primary form of mitral valve prolapse (MVP) characterized by myxomatous degeneration, leading to excessive leaflet thickening, redundancy, and elo...
BMIs or value BCIs are the devices still in progress which create a couple connection of the outer workings of a device with a human body and brain for the purposes of a ...
Hyperlipidemia is a prevalent metabolic disorder characterized by elevated levels of plasma lipids, including cholesterol, triglycerides, and various lipoproteins such as...
Decompensated Chronic Liver Disease (DCLD) signifies the advanced stage of cirrhosis, characterized by the emergence of critical complications such as ascites, hepatic en...
Ayurveda, the ancient science of life, lays strong emphasis on the preservation of health through the principle of "Swasthasya Swasthya Raksanam"—maintaining the health...
Acid-base indicators play a crucial role in chemical analysis, industry, and everyday applications. These substances change color in response to pH variations, making the...
A straightforward, rapid, sensitive, precise, and specific UV spectrophotometric method was developed and validated for the determination of Fimasartan Potassium Trihydra...
The present study described a new, simple, accurate and precise development for estimation of selexipag by RP Agilent Tech. Gradient System with Auto injector, UV (DAD)...
Jasminum officinale L. (Oleaceae), commonly known as common jasmine, has been traditionally employed in multiple medicinal systems. This study comprehensively evaluates i...
Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by symmetric joint inflammation, leading to joint pain, swelling, and eventually joint damage and ...
The potential of cannabis to treat medical problems has drawn more attention. The adverse effects of exposure can be unpredictable because to the variety of cannabis-base...
Oral squamous cell carcinoma (OSCC) is one of the most deadly diseases in the head and neck region, accounting for one-third of all head and neck cancer deaths. Mortality...
Microspheres are free flowing powders having particle size in the range of 1-1000µm with biologically active drugs intended for providing constant and prolonged therapeu...
The plant Erythrina variegata is traditional medicinal plant. Different parts of Erythrina variegata have used in traditional medicine as nervine sedative, febrifuge, ant...
Multiple Myeloma (MM) is a hematological malignancy marked by the proliferation of abnormal plasma cells in the bone marrow, leading to multiple systemic complications in...
Pharmacovigilance (PV), also referred to as drug safety, encompasses the science and activities involved in detecting, assessing, understanding, and preventing adverse dr...
Most of the pharmaceuticals are analyzed using UV-Visible methods due to their simplicity, better understanding for students, and economy. Ammonia and primary amino group...
Pogostemon parviflorus Benth (Lamiaceae), Houttuynia cordata Thunb (Saururaceae) and Solanum spirale Roxb (Solanacea) are traditionally used as vegetables to cure stomach...
The blue-green algae (Cyanoprokaryotes) are considered as one of the most ancient microorganisms. The members of this group are capable to perform oxygenic photosynthesis...
India has one of the world's highest diabetes burdens. As of 2024, an estimated 89.8 million individuals (20-79 years old) in India have diabetes, with the figure expect...
Diuretics are mainly used in the management of hypertension, chronic kidney disease (CKD), heart failure, and numerous hypervolemic disorders. Different diuretics work on...
Acne vulgaris is a common dermatological condition affecting individuals of all age groups, especially adolescents. Conventional therapies often cause side effects like d...
A new and improved pharmaceutical dosage form called a bilayer tablet was created to get around some of the drawbacks of traditional single-layer tablets. Because of thei...
Hypertension affects over 1.13 billion people worldwide and remains a leading risk factor for cardiovascular disease, stroke, and kidney disease. While conventional antih...
Levulinic acid (LA) is a bio-based platform chemical with wide-ranging applications in food, fuel, and pharmaceuticals. Its derivatives—such as sodium, calcium, methyl,...
Objectives: This study aimed to study the in-vitro studies on antidiabetic and antioxidant activity of Hydroalcoholic extract of Barleria prionitis linn. The objectives i...
Printing technology is a rising innovation with the quickest beginning in the oral thin film manufacturing techniques. While the printing technology already enables a pre...
The present investigation was aimed to determine the “Study on Marketing of Medicinal Plants (Insulin Plant) [6] This plant mostly known as a decorative plant in India,...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that presents with a variety of clinical symptoms and unpredictable flare-ups. Hydroxychloroquine (HCQ)...
This review focus on polyherbal extract having Anti-inflammatory activity. This consists essential oil of poly-herb such as turmeric, peppermint, ginger. Turmeric is a rh...
The recent past in the technological development evidenced that evolution in Nanotechnology and nanoscience is the key factor. Nanotechnology is multidisciplinary science...
Diabetes mellitus is a major global health concern, affecting millions of people. Existing treatments, including as insulin injections and oral medicines, assist manage ...
Norovirus is a highly contagious, non-enveloped RNA virus that is recognized as the leading cause of acute gastroenteritis across all age groups globally. It belongs to t...
Langya henipavirus (Lay V) is an emerging zoonotic pathogen belonging to the Henipavirus genus, closely related to the highly pathogenic Nipah and Hendra viruses. First d...
Veliparuthi (Pergularia daemia) (Family: Apocynaceae) is also known as uthamani in Tamil, utaran in Hindi, and trellis-0vine in English. It is medicinal plant with variou...
3Products known as nutraceuticals are utilized as medicines in addition to being used for nourishment. A substance that has physiological benefit3s or offers protection a...
The main objective of this study was to formulate and evaluate the oral dispersible tablets of amlodipine besylate with natural and synthetic super disintegrants. Various...
The practice of self-medication, especially among college students, is increasingly recognized as a significant public health issue globally. It involves individuals inde...
By improving diagnostic accuracy , expediting treatment planning and facilitating data-driven clinical decision making ,Artificial Intelligence (AI) is transforming the H...
Chandipura virus (CHPV), a member of the Rhabdoviridae family and Vesiculovirus genus, is an emerging neurotropic virus identified primarily in India. It causes acute enc...
Herbal formulations have long been integral to traditional medical practices and are increasingly acknowledged in modern healthcare for their natural origins and therapeu...
Herbal Medicine sometimes referred to as Herbalism or Botanical Medicine, is the use of herbs for their therapeutic or medicinal value. The herb is a plant or plant part ...
The poor aqueous solubility of many newly developed drugs, particularly those categorized as Biopharmaceutics Classification System (BCS) Class II, limits their o...
Itraconazole (ITZ), a poorly water-soluble antifungal drug, exhibits limited oral bioavailability, which hampers its therapeutic efficacy. This study aimed to develop a n...
Ocular drug delivery is a complex and challenging area due to various anatomical and physiological barriers that limit drug penetration and retention. Conventional eye dr...
Punarnava is the ancient medicinal plant belongs to the Nyctaginaceae family. It is available in three different species B.diffusa, B.verticillata, T.portulaca there root...
This review delves into the intricate pharmacodynamics of polysaccharides in the realm of cancer therapy. Polysaccharides, long regarded for their multifaceted biological...
Green tea is known for its strong antioxidant and health-promoting properties. This review focuses on the compounds in green tea—mainly catechins and polyphenols—that...
Acrylamide, a potentially harmful compound, is formed in starchy foods during high-temperature cooking processes such as baking, frying, and roasting through the Maillard...
Mouth dissolving films (MDFs), also known as oral thin films (OTFs), have emerged as a novel and innovative drug delivery system designed to enhance patient compliance, p...
Curcumin is a hydrophobic component that shows anti-cancer, antioxidant properties but it faces problem for its bioavailability. To overcome this problem Curcumin is enca...
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycaemia resulting from impaired insulin secretion, insulin action, or both. The two p...
Antibiotics have been a cornerstone of modern medicine since their discovery, transforming the treatment of bacterial infections and significantly reducing mortality and ...
In HPLC method, Methanol and Water (75:25 % v/v) was used as mobile phase, at a flow rate of 1.0 ml/min, on HPLC system containing UV- detector with Openlab EZchrome soft...
Zika virus (ZIKV), a mosquito-borne flavivirus, has emerged as a significant global health threat following widespread outbreaks in Americas and Pacific regions. Initiall...
Cubosomes, which are self-assembled nanostructures derived from amphiphilic lipids in the presence of stabilizing agents, represent a significant advancement in the field...
The accurate estimation of active pharmaceutical ingredients (APIs) is essential in ensuring the safety, efficacy, and quality of pharmaceutical products. This review pre...
Oral disintegrating films (ODFs) have emerged as a novel and versatile platform in drug delivery, offering an effective alternative to conventional dosage forms, especial...
This study investigates the anticancer potential of three newly designed compound (1a, 1b, and 1c) using molecular docking and in silico ADMET profiling. All compounds de...
The present study focuses on the formulation and evaluation of mucoadhesive buccal tablets of Repaglinide using Carbopol 934P and HPMC K4M as primary polymers to enhance ...
Allopathic medicine, the mainstream system of healthcare, relies extensively on scientifically developed formulations to ensure the safe, effective, and targeted delivery...
The prevalence of cancer around the world emphasises how urgently novel treatments are needed. Because of their wide range of pharmacological characteristics, A class of ...
This review provides a comprehensive and up-to-date exploration of indole and its derivatives, focusing on their evolving role in medicinal chemistry. Indole, a privilege...
One of the most important and complex phases of drug development is lead optimization (LO), which turns early "hit" molecules into promising therapeutic candidates. The g...
The development of herbal medicines has long been grounded in traditional healing systems. However, recent technological innovations are significantly transforming this f...
Emulgels represent the next big step in topical drug delivery by combining the benefits of emulsions and gels with a view to enhancing the therapeutic efficacy of hydroph...
Drugs that are poorly soluble in water can have their oral bioavailability and solubility increased with the use of amorphous solid dispersions (ASDs). Numerous technique...
To evaluate the anti-asthmatic activity of Euphorbia hirta through pharmacological assessment and phytochemical screening. The research focuses on identifying bioactive c...
Hyperacidity, commonly referred to as acid reflux, is a gastrointestinal condition caused by excessive hydrochloric acid production in the stomach. This condition can lea...
Central nervous system (CNS) disorders represent a major global health burden necessitating precise and reliable quantification of CNS-active pharmaceutical ingre...
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Its...
Satureja hortensis L., commonly known as summer savory, is a widely used aromatic and medicinal plant belonging to the Lamiaceae family. Traditionally utilized in folk me...
This review critically assesses various strategies for the isolation of bioactive from dandelion (Taraxacum officinale), which covers both traditional methods such as mac...
The present study focuses on the formulation and evaluation of a herbal face wash gel using natural ingredients known for their skincare benefits. The main objective was ...
The key component of a medication's efficacy, regardless of the administration mode, is its solubility. Numerouslatelyindustrializedmedicinesremain poorly bioavailable ow...
CRISPR- Cas systems are a new game-changer in genetic engineering conceptually, as a technique that has much improved speed, specificity, and ease of use for editing gene...
Developing a novel topical Smilax China microemulsion drug delivery system was the aim of the project. In order to identify the essential components that will be used in ...
The crude solvents, varying degree of polarity solvents were used to extract Uraria picta. This study used the procedures of a potential antioxidant including DPPH study ...
Background: Mefenamic acid (MA), a BCS Class II drug, exhibits poor aqueous solubility and an intensely bitter taste, which limit its oral bioavailability and patient com...
Diabetes mellitus is a chronic metabolic disorder with a rapidly increasing global prevalence, leading to severe microvascular and macrovascular complications. The manage...
Microalgae carry out photosynthesis very efficiently, turning 8 to 10% of solar energy into biomass. They have ways to concentrate CO?, which helps them outperform land-b...
Bougainvillea glabra belonging to Nyctaginaceae family includes the widely grown ornamental plant, which is becoming more well-known for its many therapeutic uses. Flavon...
Herbal medicines have been used since many centuries. In the search for new therapeutic options, novel bio-molecules of natural sources are to be investigated. Purpose of...
Chronic postoperative pain (CPOP) is a common and serious problem for many patients after surgery. Even with pain relievers and various pain management plans, many still ...
Hibiscus hispidissimus Griffith belonging to the family, Malvaceae is a traditionally valued but little-studied medicinal plant with substantial pharmacological potential...
Calvarial abnormalities compromise neurological protection and cranial integrity. These cranial abnormalities are defined by the partial or whole absence of cranial vault...
Oxadiazole derivatives have emerged as a vital class of heterocyclic compounds in medicinal chemistry due to their diverse pharmacological activities and favorable drug-l...