Department of Pharmaceutics, Samarth Institute of Pharmacy, Belhe, Maharashtra, India
Several illnesses affecting humans are progressing much more quickly due to modern lifestyle choices, eating habits, stress, environmental variables, and extensive use of synthetic chemicals in food processing and agriculture. Worldwide, researchers have been searching for natural therapeutics that can be utilized to either treat or postpone the onset of various lifestyle-related illnesses. Due to the presence of various bioactive chemicals, several different kinds of medicinal plants have demonstrated the potential to be commonly used in therapies. Some of them are Fenugreek seeds, Flaxseeds and Curry leaves. Each of these natural ingredients is rich in bioactive compounds, including dietary fibers, essential fatty acids, alkaloids, and polyphenols, which contribute to their diverse pharmacological effects. Fenugreek seeds are known for their anti-diabetic, hypocholesterolemic, and gastroprotective activities. Flaxseeds, a potent source of alpha-linolenic acid (ALA) and lignans, are linked to cardiovascular protection, hormonal balance, and anti-inflammatory effects. Curry leaves, widely recognized for their antioxidant, hepatoprotective, and antidiabetic properties, are also a vital source of essential micronutrients. This review consolidates recent scientific findings and traditional knowledge to highlight the preventive and therapeutic potential of these ingredients.
In recent years, there has been a growing global interest in the use of natural, plant-based ingredients for the prevention and management of various health conditions. Among these, Fenugreek seeds, Flaxseeds and Curry leaves have garnered significant attention due to their rich phytochemical profiles and wide-ranging therapeutic properties. Traditionally used in Ayurvedic and other indigenous medical systems, these ingredients are now being recognized by modern science for their numerous health-promoting effects. Fenugreek seeds are a rich source of dietary fiber, saponins, alkaloids, flavonoids, and amino acids such as 4-hydroxyisoleucine. These compounds are associated with antidiabetic, hypolipidemic, and anti-inflammatory activities, making fenugreek an effective functional food for managing metabolic disorders. Similarly, flaxseeds are packed with alpha-linolenic acid (ALA), lignans, and mucilage, offering potent antioxidant, cardioprotective, and hormone-balancing benefits. Their consumption has been linked to improved cardiovascular health, reduced inflammation, and potential anticancer properties. Curry leaves, a staple in Indian cuisine, are not only flavor enhancers but also a source of numerous bioactive compounds such as carbazole alkaloids, phenolics, and essential oils. These compounds have been shown to possess antioxidant, hepatoprotective, antidiabetic, and neuroprotective effects. The traditional use of curry leaves in managing diabetes, gastrointestinal issues, and hair and skin conditions is now being substantiated by scientific studies.
This review aims to provide a comprehensive overview of the nutritional composition, pharmacological activities, and potential health benefits of fenugreek seeds, flaxseeds, and curry leaves. By integrating traditional knowledge with current research, this paper seeks to highlight their role as functional foods.
1] Fenugreek:
Taxanomical classification:
Figure 1: Fenugreek seeds
Pharmacological Activities/Health benefits of Fenugreek Seeds
Helps regulate blood glucose levels by improving insulin sensitivity and slowing carbohydrate absorption.
Reduces total cholesterol, LDL, and triglycerides while increasing HDL levels.
Rich in flavonoids and polyphenols that neutralize free radicals and reduce oxidative stress.
Exhibits anti-inflammatory properties through suppression of inflammatory mediators.
Effective against certain bacteria and fungi due to its bioactive compounds.
Contains phytoestrogens that may help in relieving symptoms of menopause and enhancing lactation.
2] Flaxseed:
Taxanomical classification:
Figure 2: Flaxseed.
Pharmacological Activities/Health benefits of Flaxseed:
Rich in lignans and polyphenols that neutralize free radicals and reduce oxidative stress.
Alpha-linolenic acid (ALA) and lignans help suppress inflammatory pathways.
Lowers blood pressure, reduces LDL cholesterol, and improves arterial health.
Improves insulin sensitivity and helps in glycemic control.
Lignans may reduce the risk of hormone-related cancers, such as breast and prostate cancer.
Protects liver tissue from damage due to toxins or metabolic stress.
Shows mild activity against certain bacteria and fungi due to bioactive compounds.
Mucilage content supports gut health and acts as a natural laxative.
3] Curry Leaves:
Figure 3: Curry Leaves
Rich in carbazole alkaloids, flavonoids, and phenolic compounds that protect cells from oxidative damage.
Helps regulate blood glucose by enhancing insulin secretion and improving glucose metabolism.
Exhibits antibacterial, antifungal, and antiviral properties due to essential oils and alkaloids.
Protects the liver from toxins and supports liver function.
Reduces inflammation through inhibition of pro-inflammatory enzymes and cytokines.
Helps lower cholesterol and triglycerides, supporting heart health.
May enhance memory and cognitive function; studied for potential in neurodegenerative disease prevention.
Certain bioactive compounds may help inhibit the growth of cancer cells in vitro.
CONCLUSION:
Flaxseed, curry leaves, and Fenugreek have been found to possess a range of pharmacological activities and potential health benefits. These ingredients have been traditionally used in various cultures for their medicinal properties, and modern research has validated their potential uses. Flaxseed is rich in omega-3 fatty acids, fiber, and lignans, flaxseed has been shown to have anti-inflammatory, antioxidant, and cardiovascular-protective effects. Curry leaves have been found to have antioxidant, anti-inflammatory, and antimicrobial properties, with potential benefits for cardiovascular health, diabetes management, and cognitive function. Fenugreek has been traditionally used to manage blood sugar levels, improve digestive health, and support lactation. Modern research has confirmed its potential benefits for glucose metabolism, lipid profiles, and antioxidant status.
REFERENCES
Arote Sneha*, Gaikwad Rutuja, A Review on Potential Health Benefits of Fenugreek Seeds, Flaxseeds and Curry Leaves, Int. J. of Pharm. Sci., 2025, Vol 3, Issue 4, 1934-1938. https://doi.org/10.5281/zenodo.15224584