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Abstract

The pharmaceutical industry is witnessing remarkable advancements in the packaging of medicines to ensure the safety, efficacy, and convenience of drug delivery. This project explores the multifaceted landscape of pharmaceutical packaging, encompassing primary, secondary, and tertiary packaging solutions, each serving distinct yet interconnected functions. The ideal characteristics of pharmaceutical packaging are examined, emphasizing the critical role of preserving product integrity and patient safety. Additionally, this project delves into cutting-edge developments in pharmaceutical packaging, such as child-resistant packaging to safeguard against accidental ingestion, anti-counterfeiting measures to combat the proliferation of counterfeit drugs, and innovative technologies like blow-fill-seal and pre-fill syringes, which offer efficiency and precision in drug administration. The study also investigates the incorporation of tamper-evident features in pharmaceutical packaging to enhance consumer confidence and protect against product tampering. By exploring these vital aspects, this project sheds light on how advancements in pharmaceutical packaging are not only ensuring the quality and safety of medicines but also contributing to the overall well-being of patients and the integrity of the pharmaceutical supply chain.

Keywords

Pharmaceutical packaging, Drug safety, Child-resistant packaging, Anti-counterfeiting measures, Innovative packaging technologies, Tamper-evident features..

Reference

  1. Chordiya SV, Garge BM. Innovative packaging of medicines.
  2. Pareek VI, Khunteta AL. Pharmaceutical packaging: current trends and future. Int J Pharm Sci. 2014 Jun 6;6(6):480-5.
  3. Mittal S, Wadhwani B, Lakhani M. Innovations in Pharma Packaging Technologies. Journal of Young Pharmacists. 2021;13(3):197.
  4. Kulkarni S, Agrawal A, Sharma SB, Jain S. Creative innovations in pharmaceutical packaging. Indian Journal of Pharmacy and Pharmacology. 2015;2(4):230-5.
  5. Rydzkowski T, Wróblewska-Krepsztul J, Thakur VK, Królikowski T. Current trends of intelligent, smart packagings in new medical applications. Procedia Computer Science. 2022 Jan 1; 207:1271-82.
  6. Zadbuke N, Shahi S, Gulecha B, Padalkar A, Thube M. Recent trends and future of pharmaceutical packaging technology. Journal of pharmacy & bioallied sciences. 2013 Apr;5(2): 98.
  7. Amarji B, Kulkarni A, Deb PK, Maheshwari R, Tekade RK. Package development of pharmaceutical products: Aspects of packaging materials used for pharmaceutical products. In Dosage Form Design Parameters 2018 Jan 1 (pp. 521-552). Academic Press
  8. Munzel J. Marketing innovation: Pharmaceutical packaging: Technology and design requirements are on the rise. Journal of Medical Marketing. 2007 Mar;7(2):136-45.
  9. Nasa P. A review on pharmaceutical packaging material. World Journal of Pharmaceutical Research. 2014 May 22;3(5):344-68.
  10. Lukesh Pegu PC, Chandrul MK. Pharmaceutical Packaging Technology.
  11. Deore SD, Gajmal GK, Jadhav SP, Patil DM, Sonawane DD. Study of different methods of Pharmaceutical Packaging.
  12. Singh A, Sharma PK, Malviya R. Eco friendly pharmaceutical packaging material. World Applied Sciences Journal. 2011 May;14(11):1703-16.
  13. Patel PR, Gowrav MP, Vamsi B. INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES.
  14. Cited by: https://link.springer.com/chapter/10.1007/978-3-030-84977-1_5
  15. UPDATE II. Advanced Biomedical & Pharmaceutical Research.
  16. Baldaniya L, Shah V, Maniar M, Gohel M, Thakkar V, Gandhi T. Innovative Child-Resistant Packaging for Pharmaceutical Solid Dosage Forms. Journal of Packaging Technology and Research. 2019 Oct; 3:235-42.
  17. Dobrucka R. RECENT TRENDS IN PACKAGING SYSTEMS FOR PHARMACEUTICAL PRODUCTS. LogForum. 2014 Dec 1;10(4).
  18. Nesterenko TO, Bezpala YO. Special pharmaceutical packaging with function of «Protection» from children.
  19. Shah RY, Prajapati PN, Agrawal YK. Anticounterfeit packaging technologies. Journal of advanced pharmaceutical technology & research. 2010 Oct 1;1(4):368-73.
  20. Devi KV, Burande M, Deepak H, Jobanputra SB. Packaging solutions to the changing pharma market needs. Pharma Times. 2007; 39:29-34.
  21. Soon JM, Manning L. Developing anti-counterfeiting measures: The role of smart packaging. Food Research International. 2019 Sep 1; 123:135-43.
  22. Mehdi S, Mehdi S, Ahmed A, Ahmed N, Aslam W, Afzal U, Majeed K, Yazdan UE, Mushtaq U, Shafiq S. Anti-counterfeit technologies.
  23. Bansal D, Malla S, Gudala K, Tiwari P. Anti-counterfeit technologies: a pharmaceutical industry perspective. Scientia pharmaceutica. 2013 Mar;81(1):1-4.
  24. Bondre S, Puttewar T, Patil RY. Review: a focus on blow-fill-seal technology. Adv Res Pharm Biol. 2013;3(4):494-9.
  25. Reed CH. Recent technical advancements in blow-fill-seal technology. Business briefing: pharmagenerics. 2002:1-4.
  26. Liu W, Faulhaber S, Sane S, Lam P. Biopharmaceutical manufacturing using blow–fill–seal technology. BioPharm International. 2011 Jul 1;24(7).
  27. Ingle RG, Agarwal AS. Pre-filled syringe–a ready-to-use drug delivery system: a review. Expert Opinion on Drug Delivery. 2014 Sep 1;11(9):1391-9.
  28. GANGANE PS, MAHAJAN NM, AHAJAN UN, HIRANWAR SR. Delivering Biologics in Prefilled Syringes: An innovation in parenteral packaging. International Journal of Pharmacy Research & Technology (IJPRT). 2020;10(1):58-66.
  29. Makwana S, Basu B, Makasana Y, Dharamsi A. Prefilled syringes: an innovation in parenteral packaging. International journal of pharmaceutical investigation. 2011 Oct;1(4):200.
  30. Sacha G, Rogers JA, Miller RL. Pre-filled syringes: a review of the history, manufacturing and challenges. Pharmaceutical development and technology. 2015 Jan 2;20(1):1-1.
  31. Kale NS, Kazi A, Kale SS. Drug prefilled non-reusable syringes as drug-device. World Journal of Pharmaceutical Sciences. 2015 Oct 3:2095-110.
  32. Kumar AK, Gupta NV, Lalasa P, Sandhil S. A review on packaging materials with anti-counterfeit, tamper-evident features for pharmaceuticals. Int. J. Drug Dev. Res. 2013 Jul; 5:26-34.
  33. Lockhart H, Paine FA, Lockhart H, Paine FA. Tamper-evident packaging. Packaging of Pharmaceuticals and Healthcare Products. 1996:172-87.
  34. Rösler S. Empirical Analyses of Anti-Counterfeiting and Tamper Evidence Techniques in Pharma Packaging Applications.
  35. Pharmaceutical serialization: Impact on drug packaging Shambhu Sarkar
  36. Tamper EvidenceÐa Vital Issue in Packaging Development?2; By Rolf Jansen* and Guido Schelhove
  37. Otoshi K, Tomita H, Kaneko T. RFID Solutions for the medical and pharmaceutical industries. Hitachi Review. 2007 Sep; 56:83
  38. Forcinio H. What can radio frequency identification do for pharmaceutical packaging. Pharmaceutical Technology. 2003 May;27(5):34-9

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Nikam Manik
Corresponding author

Department Of Pharmaceutics,Divine College Of Pharmacy ,Satana

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Madhuri Davange
Co-author

Department Of Pharmaceutics, Divine College Of Pharmacy, Satana

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Dhananjay Patil
Co-author

Department Of Pharmaceutics, Divine College Of Pharmacy, Satana

Saurabh M. Nikam, Madhuri D. Davange, Dhananjay M Patil., A Review On Advancements In The Packaging Of Medicines, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 416-432. https://doi.org/10.5281/zenodo.10389787

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