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Abstract

This review article represents the collection and discussion of various analytical methods available in the literature for the simultaneous estimation of Naloxone and Buprenorphine in pharmaceutical and biological samples consisting of HPLC, UV-visible method, near-IR spectroscopy, spectrofluorometry, and hyphenated techniques such as LC-MS, LC-MS/MS, UPLC-MS/MS, and GC-MS. The anticipated review provides details about the comparative utilization of various analytical techniques for the determination of Naloxone and Buprenorphine. When it comes to offering solutions like development, analytical techniques are crucial. An overview and classification of the many analytical techniques used to identify supply issues will be provided in this article. In the quality assurance and internal control of the majority of pharmaceutical medications and preparations, pharmaceutical analysis plays a special function. The need for innovative analytical methods in the pharmaceutical business has increased as a result of the fast development of the pharmaceutical and pharmaceutical industries in many regions of the world. So, developing one's analytical abilities has become a beneficial learning process. Analytical equipment improvements have led to recent breakthroughs in analytical procedures.

Keywords

Naloxone, Buprenorphine, Analytical methods, Pharmacology, Pharmacokinetics, HPLC Method

Reference

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Kalpana C. Sable
Corresponding author

Department of Quality Assurance, PRES College of Pharmacy (Women’s), Chincholi, Nashik

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Vinayak M. Gaware
Co-author

Department of Pharmaceutical Chemistry, PRES College of Pharmacy (Women’s), Chincholi, Nashik

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Mayur T. Gaikar
Co-author

Department of Pharmaceutical Chemistry, PRES College of Pharmacy (Women’s), Chincholi, Nashik

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Vivekanand A. Kashid
Co-author

Dr. Kolpe Institute of Pharmacy, Kolpewadi, Kopargaon, Ahmednagar

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Jaya V. Mehetre
Co-author

Department of Quality Assurance, PRES College of Pharmacy (Women’s), Chincholi, Nashik

Kalpana C. Sable*, Vinayak M. Gaware, Mayur T. Gaikar, Vivekanand A. Kashid, Jaya V. Mehetre, Trupti P.Bhalekar, A Review On Analytical Methods For Estimation Of Naloxone Hcl And Buprenorphine Hcl In Pharmaceutical Dosage Form, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 6, 27-38. https://doi.org/10.5281/zenodo.8028071

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