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Abstract

The study's objective was to evaluate the rhizomes of Bergenia ligulata's antispasmodic properties. This species' roots, leaves, and petals have also been employed for numerous medical conditions. The gastrointestinal tract is in responsible of consuming and digesting food, as well as absorbing nutrients and getting rid of any leftover waste. Numerous illnesses that affect the GI system might negatively affect digestion and overall health. Diarrhoea, IBS (Irritable Bowel Syndrome), constipation, peptic ulcer, and other digestive issues are common. GIT disorders are any disease that affects the gastrointestinal tract. This group includes any symptoms that manifest in the middle or lower gastrointestinal system. The goal of this study was to examine the antispasmodic activity of rhizomes of Bergenia ligulata on the voluntary motility and contractility of the smooth muscle of chicken ileum invitro The study uses chicken ileum to assess the antispasmodic effects of Bergenia ligulata rhizomes on intestinal contraction. Traditional treatments for GIT diseases include the use of botanicals like Zingiber officinale, Glycyrrhiza uralensis, Artemisia vulgaris, etc. As a result of this investigation, it was determined that Bergenia ligulata rhizome methanolic extract has antispasmodic properties in intestinal tissue, suggesting its potential use as an antidiarrheal medication.

Keywords

Bergenia ligulata, Antispasmodic, antidiarrhoeal, Bergenia rhizome, GIT disorders

Reference

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Ananya Bhattacharjee
Corresponding author

Himalayan Pharmacy Institute, Majhitar, Sikkim-737136.

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Abhijit Mishra
Co-author

Himalayan Pharmacy Institute, Majhitar, Sikkim-737136.

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Ankita Adhikari
Co-author

Himalayan Pharmacy Institute, Majhitar, Sikkim-737136.

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Benazeer Ali
Co-author

Himalayan Pharmacy Institute, Majhitar, Sikkim-737136.

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Pratham Gurung
Co-author

Himalayan Pharmacy Institute, Majhitar, Sikkim-737136.

Abhijit Mishra, Ankita Adhikari, Benazeer Ali, Pratham Gurung, Rupam Kalita, Ananya Bhattacharjee, In-Vitro Evaluation of Antispasmodic Activity Of Rhizomes Of Bergenia Ligulata, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 7, 182-189. https://doi.org/10.5281/zenodo.8121954

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