Archive

  • Lifestyle Medicine Encompassing Scientific Exercises and Right Diet The Key To Prevent And Reverse PCOS PCOD Poly Cystic Ovarian Syndrome Polycystic Ovarian Disease
  • 1,4(CEO), Dr. Bala’s School of Fitness & Preventive Medicine, Faridabad, Delhi-NCR, India
    2General Surgery General and Laparoscopic Surgeon, Senior Resident, Department of General Surgery, Pondicherry Institute of Medical Sciences, Puducherry
    3(IAS), Additional Principal Secretary to the Chief Minister of Haryana, Director General-Information, Public Relations, Languages & Culture, Haryana,
    4Advocate, Supreme court of India, Delhi, 110 001, India
    5Punjab Cricket Association, Chandigarh, 160 002, India
    6Dean, Research and Development Center, Sethu Institute of Technology, Pullor, Kariyapatti, India

Abstract

Polycystic ovary syndrome (PCOS) is of clinical and public health importance as it is very common, affecting up to one in five women of reproductive age. It has significant and diverse clinical implications including reproductive (infertility, hyperandrogenism, hirsutism), metabolic (insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, adverse cardiovascular risk profiles) and psychological features (increased anxiety, depression and worsened quality of life). Obesity worsens the presentation of PCOS and weight management (weight loss, maintenance or prevention of excess weight gain) is proposed as an initial treatment strategy, best achieved through lifestyle changes incorporating diet, scientific exercises and behavioral interventions.

Keywords

Polycystic ovary syndrome, clinical implications, lifestyle strategies, obesity, insulin resistance and infertility

Reference

  1. Clark, A.M., Thornley, B., Tomlinson, L., Galletley, C. and Norman, R.J., 1998. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Human Reproduction (Oxford, England), 13(6), pp.1502-1505.
  2. Legro, R.S. and Strauss III, J.F., 2002. Molecular progress in infertility: polycystic ovary syndrome. Fertility and sterility, 78(3), pp.569-576
  3. Hoeger, K.M., Dokras, A. and Piltonen, T., 2021. Update on PCOS: consequences, challenges, and guiding treatment. The Journal of Clinical Endocrinology & Metabolism, 106(3), pp.e1071-e1083.
  4. Teede, Helena J., Marie L. Misso, Jacqueline A. Boyle, Rhonda M. Garad, Veryan McAllister, Linda Downes, Melanie Gibson?Helm et al. "Translation and implementation of the Australian?led PCOS guideline: clinical summary and translation resources from the International Evidence?based Guideline for the Assessment and management of polycystic ovary syndrome." Medical journal of Australia 209 (2018): S3-S8.
  5. Goodpaster, B.H., Kelley, D.E., Thaete, F.L., He, J. and Ross, R., 2000. Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content. Journal of applied physiology, 89(1), pp.104-110.
  6. Marzouk, T.M. and Ahmed, W.A.S., 2015. Effect of dietary weight loss on menstrual regularity in obese young adult women with polycystic ovary syndrome. Journal of pediatric and adolescent gynecology, 28(6), pp.457-461.
  7. Sheikh, I.A., Turki, R.F., Abuzenadah, A.M., Damanhouri, G.A. and Beg, M.A., 2016. Endocrine disruption: computational perspectives on human sex hormone-binding globulin and phthalate plasticizers. PloS one, 11(3), p.e0151444.
  8. Higgins, J.P., Altman, D.G., Gøtzsche, P.C., Jüni, P., Moher, D., Oxman, A.D., Savovi?, J., Schulz, K.F., Weeks, L. and Sterne, J.A., 2011. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. Bmj, 343.
  9. Lim, S.S., Hutchison, S.K., Van Ryswyk, E., Norman, R.J., Teede, H.J. and Moran, L.J., 2019. Lifestyle changes in women with polycystic ovary syndrome. Cochrane Database of Systematic Reviews, (3).
  10. Alqarni, A., Manlapaz, D., Baxter, D., Tumilty, S. and Mani, R., 2018. Test procedures to assess somatosensory abnormalities in individuals with neck pain: a systematic review of psychometric properties. Physical Therapy Reviews, 23(6), pp.301-316
  11. Faghfoori, Z., Fazelian, S., Shadnoush, M. and Goodarzi, R., 2017. Nutritional management in women with polycystic ovary syndrome: A review study. Diabetes & metabolic syndrome: Clinical research & reviews, 11, pp.S429-S432.
  12. Szczuko, M., Kikut, J., Szczuko, U., Szyd?owska, I., Nawrocka-Rutkowska, J., Zi?tek, M., Verbanac, D. and Saso, L., 2021. Nutrition strategy and life style in polycystic ovary syndrome—Narrative review. Nutrients, 13(7), p.2452.
  13. Szczuko, M., Kikut, J., Szczuko, U., Szyd?owska, I., Nawrocka-Rutkowska, J., Zi?tek, M., Verbanac, D. and Saso, L., 2021. Nutrition strategy and life style in polycystic ovary syndrome—Narrative review. Nutrients, 13(7), p.2452.
  14. Malik. T.H., Ali. H., Hassan. A., Qayyum. J and Naseem.A., 2021. . Pharmacotherapy and Neoteric Dietary Approaches for Polycystic Ovary Syndrome: A Systematic Review. Turkish Journal of Endocrinology & Metabolism, 25(1).
  15. González-Becerra, K., Ramos-López, O., Barrón-Cabrera, E., Riezu-Boj, J.I., Milagro, F.I., Martínez-López, E. and Martínez, J.A., 2019. Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review. Lipids in health and disease, 18(1), pp.1-18.
  16. Diao, P., Wang, X., Jia, F., Kimura, T., Hu, X., Shirotori, S., Nakamura, I., Sato, Y., Nakayama, J., Moriya, K. and Koike, K., 2020. A saturated fatty acid-rich diet enhances hepatic lipogenesis and tumorigenesis in HCV core gene transgenic mice. The Journal of Nutritional Biochemistry, 85, p.108460.
  17. Hoover, S.E., Gower, B.A., Cedillo, Y.E., Chandler-Laney, P.C., Deemer, S.E. and Goss, A.M., 2021. Changes in Ghrelin and Glucagon following a Low Glycemic Load Diet in Women with PCOS. The Journal of Clinical Endocrinology & Metabolism, 106(5), pp.e2151-e2161.
  18. Dougkas, A. and Östman, E., 2016. Protein-enriched liquid preloads varying in macronutrient content modulate appetite and appetite-regulating hormones in healthy adults. The Journal of nutrition, 146(3), pp.637-645.
  19. Shang, Y., Zhou, H., Hu, M. and Feng, H., 2020. Effect of diet on insulin resistance in polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism, 105(10), pp.3346-3360.
  20. Li, J., Bai, W.P., Jiang, B., Bai, L.R., Gu, B., Yan, S.X., Li, F.Y. and Huang, B., 2021. Ketogenic diet in women with polycystic ovary syndrome and liver dysfunction who are obese: A randomized, open?label, parallel?group, controlled pilot trial. Journal of Obstetrics and Gynaecology Research, 47(3), pp.1145-1152.
  21. Paoli, A., Mancin, L., Giacona, M.C., Bianco, A. and Caprio, M., 2020. Effects of a ketogenic diet in overweight women with polycystic ovary syndrome. Journal of translational medicine, 18(1), pp.1-11.
  22. Singh, S., Singh, K. and Singh, M., 2010. Anthropometric measurements, body composition and somatotyping of high jumpers. Brazilian Journal of Biomotricity, 4(4), pp.266-271.
  23. Mooney, S.J., Baecker, A. and Rundle, A.G., 2013. Comparison of anthropometric and body composition measures as predictors of components of the metabolic syndrome in a clinical setting. Obesity research & clinical practice, 7(1), pp.e55-e66.
  24. Szczuko, M., Kikut, J., Szczuko, U., Szyd?owska, I., Nawrocka-Rutkowska, J., Zi?tek, M., Verbanac, D. and Saso, L., 2021. Nutrition strategy and life style in polycystic ovary syndrome—Narrative review. Nutrients, 13(7), p.2452.
  25. Lobo, R.A. and Carmina, E., 2000. The importance of diagnosing the polycystic ovary syndrome. Annals of internal medicine, 132(12), pp.989-993.
  26. Dokras, A., 2008, January. Cardiovascular disease risk factors in polycystic ovary syndrome.In Seminars in reproductive medicine (Vol. 26, No. 01, pp. 039-044).© Thieme Medical Publishers.
  27. Szczuko, M., Zapa?owska-Chwy?, M., Drozd, A., Maciejewska, D., Starczewski, A., Wysoki?ski, P. and Stachowska, E., 2018. Changes in the IGF-1 and TNF-? synthesis pathways before and after three-month reduction diet with low glicemic index in women with PCOS. Ginekologiapolska, 89(6), pp.295-303

image
J.C Balachandar
Corresponding author

(CEO), Dr. Bala’s School of Fitness & Preventive Medicine, Faridabad, Delhi-NCR, India

image
S. Irshad Ahamed
Co-author

General Surgery General and Laparoscopic Surgeon, Senior Resident, Department of General Surgery, Pondicherry Institute of Medical Sciences, Puducherry

image
Amit Kumar Agrawal
Co-author

(IAS), Additional Principal Secretary to the Chief Minister of Haryana, Director General-Information, Public Relations, Languages & Culture, Haryana,

image
Baani Khanna
Co-author

Advocate, Supreme court of India, Delhi, 110 001, India

image
Dilsher Khanna
Co-author

Punjab Cricket Association, Chandigarh, 160 002, India

image
M. Jayachandran
Co-author

Dean, Research and Development Center, Sethu Institute of Technology, Pullor, Kariyapatti, India

J.C Balachandar*, S. Irshad Ahamed, Amit Kumar Agrawa, Baani Khanna, Dilsher Khanna and M. Jayachandran, Lifestyle Medicine Encompassing Scientific Exercises and Right Diet-The Key To Prevent And Reverse PCOS/PCOD (Poly Cystic Ovarian Syndrome/Polycystic Ovarian Disease), Int. J. in Pharm. Sci., 2023, Vol 1, Issue 7, 190-195. https://doi.org/10.5281/zenodo.8127852

More related articles
Regulating Artificial Intelligence: Developments A...
Durga Chavali, Biju Baburajan, Ashokkumar Gurusamy, Vinod Kumar D...
Study The Evaluation Parameters, Characterization ...
Kamalakar Sanjay Kale, Mahesh Kale , Mahesh Lodhe , Vedant kolhe ...
Formulation And Evaluation Of Herbal Anti-Bacteria...
Ms.Priyanka Raut, Mrs.Manisha Mishra, Gayatri Bawane, Ayushi Amba...
Formulation And Evaluation of Multipurpose Herbal Cream...
Akash Jayaprakash, Ahalya. S. S, Arya Babu, V. F. Sony, Vishnu Narayanan, Dr. Prasobh. G. R, Varsha....
The Stages Of Drug Discovery And Development Process...
Ganesh. U. Chavan, Vitthal. R. Gawade , ...
Antibacterial Activity And Phytochemical Analysis Of Dioscorea bulbifera (Linn) ...
Bulbul G. Karmankar , Poonam Thakare , Vijay S. Wadhai , ...
Related Articles
To prepare suspension of Digitalis for congestive heart failures....
Dnyandeep Jadhav , Dipak S. Borse , Chaitanya G. Baviskar , Arvind K. Hatkar, Rajendra M. Kawade, ...
Assessment Of Free Radical In Ethyl Acetate Extract Of Pandanus Julianettii Frui...
Krisna Dewi, Helmina Pigai, Eva S. Simaremare, Septiani Mangiwa, Aliya Rysbekova, Erpina S. M. Nadea...
The pharmacognostic study, phytochemical screening, and TLC of Allamanda Cathart...
Namrata M. Waghmare , Manisha G. Pate, Jayshree S. Dalal, Prasad P. Jumde , ...
Implants For Cardiovascular Diseases...
Komal Bisht, Vijay Singh, Sushmita Bala , ...
Regulating Artificial Intelligence: Developments And Challenges...
Durga Chavali, Biju Baburajan, Ashokkumar Gurusamy, Vinod Kumar Dhiman, Siri Chandana Katari, ...
More related articles
Regulating Artificial Intelligence: Developments And Challenges...
Durga Chavali, Biju Baburajan, Ashokkumar Gurusamy, Vinod Kumar Dhiman, Siri Chandana Katari, ...
Study The Evaluation Parameters, Characterization Of Zinc Oxide Lotion With Aloe...
Kamalakar Sanjay Kale, Mahesh Kale , Mahesh Lodhe , Vedant kolhe , Harshal Lokhande , Deep Lahane , ...
Formulation And Evaluation Of Herbal Anti-Bacterial Crack Heel Ointment Using Th...
Ms.Priyanka Raut, Mrs.Manisha Mishra, Gayatri Bawane, Ayushi Ambade, Alshapha Anjum Khan, Abhilasha ...
Regulating Artificial Intelligence: Developments And Challenges...
Durga Chavali, Biju Baburajan, Ashokkumar Gurusamy, Vinod Kumar Dhiman, Siri Chandana Katari, ...
Study The Evaluation Parameters, Characterization Of Zinc Oxide Lotion With Aloe...
Kamalakar Sanjay Kale, Mahesh Kale , Mahesh Lodhe , Vedant kolhe , Harshal Lokhande , Deep Lahane , ...
Formulation And Evaluation Of Herbal Anti-Bacterial Crack Heel Ointment Using Th...
Ms.Priyanka Raut, Mrs.Manisha Mishra, Gayatri Bawane, Ayushi Ambade, Alshapha Anjum Khan, Abhilasha ...