Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh
Through particular structural designs and unique preparation techniques, nanogels can encapsulate drugs within three-dimensional crosslinked polymeric networks. This allows for the controlled and sustained delivery of loaded drugs, improving patient compliance and therapeutic efficacy. Furthermore, compared to other nanocarriers, nanogels offer a better drug loading capacity and biocompatibility. The science of therapeutic biology has undergone a revolution with the use of nanoparticles in drug delivery. Drug nanocarriers are being used to extend the drug's circulation time, regulate its release and stability, and shield it from cell clearance or premature breakdown in order to increase medicinal efficacy. For more secure and reliable delivery to the intended locations, the hydrogel nanoparticle dispersions are crosslinked using a crosslinked polymeric framework. The last two decades have seen the development of nanogels as promising biomaterials with a broad range of uses. Drug accumulation in disease areas can be improved and active targeting can be accomplished with the modification of nanogels. They can be made to respond to both internal and external stimuli, including pH, temperature, light, and redox, allowing the loaded medicine to release gradually. On the other hand, there has been new research on the use of nanogels for purposes unrelated to biomedicine. Since nanogels can be used for a wide range of purposes, we have thoroughly examined the state of the art for all practical uses and production techniques of nanogels. The purpose of this note is to understand why and how nanogels are regarded as such a novel approach to drugs delivery.
Majedul Hoque*, Shuvo Nath Saha, Taharat Akram, Nanogels Based Drug Delivery System: A Promising Therapeutic Strategy, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 11, 103-111. https://doi.org/10.5281/zenodo.10070862