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Abstract

Herbal medicine, or phytotherapy, refers to the practice of using plants and their extracts for therapeutic or preventive health purposes. It forms one of the oldest healthcare systems known to humankind and remains an essential part of global medical practices today. Approximately 80% of the world’s population still relies on herbal remedies, either directly or indirectly, for healthcare needs. Herbal medicines are valued for their affordability, accessibility, and lower side-effect profile compared to synthetic pharmaceuticals. This review discusses the history, phytochemical basis, pharmacological actions, therapeutic potential, advantages, safety concerns, and future prospects of herbal medicines in the modern healthcare system.

Keywords

Phytotherapy, affordability, accessibility, ginkgo, kava kava, saw palmetto.

Introduction

Herbal remedies have been used for centuries as a type of therapy in both industrialized and underdeveloped countries. The first humans depended solely on the resources of the natural world for everything from food and shelter to medicine. These people were able to tell the difference between helpful and harmful creatures. Over 50,000 plant species are claimed to have medicinal characteristics based on research that has been published. Modern therapeutic medications like aspirin, morphine, digitoxin, and quinine owe a great deal to the scientific verification of herbal medicine1,2.

Traditional medical systems all around the world may trace their roots back to the gradual accumulation and spread of information about plant-based cures. Nutraceuticals, which include phytonutrients and herbal medicines, are becoming more popular as a means of treating a broad variety of health disorders across a wide variety of national healthcare systems. Natural remedies have been more popular over the last decade in both developed and developing nations, as seen by the widespread availability of these herbal treatments in both drugstores and food and grocery shops. Traditional medicine, which often involves the use of herbs, is seen as a key part of culture in the places where up to four billion people depend on them as their major source of healthcare3,4.

Herbal Medicine  :

The WHO has recently defined traditional medicine (including herbal drugs) as comprising therapeutic practices that have been in existence, often for hundreds of years, before the development and spread of modern is the synthesis of therapeutic experience of generations of practicing physicians of indigenous system of medicine. Traditional preparations comprise medicinal plants, minerals and organic matter etc. Herbal drugs constitute only those traditional medicines which primarily use medicinal plant preparations for therapy. The earliest recorded evidence of their use in Indian, Chinese, Egyptian, Greek, Roman and Syrian texts dates back to about 5000 years. The classical Indian texts include Rigveda, Atharvaveda, Charak Samhita and Sushruta Samhita. The herbal medicines / traditional medicaments have therefore been derived from rich traditions of ancient civilizations and scientific heritage5.

Fig No.1- Herbal Medicine

LIST OF COMMEN HERBAL  MEDICINE-7,8

TABLE NO.1 COMMON  HERBS

SR.NO.

COMMON  NAME

1

Aloe vera

2

Turmeric

3

Garlic

4

Peppermint

5

Ginseng

6

Chamomile

7

Echinacea

8

Ginkgo

9

Kava kava

10

Saw Palmetto

11

St. John’s Wort

12

Valerian

13

Lavender

14

Cinnamon

15

Ginger

COMMEN  HERAL  MEDICINES  THEIR   IUPAC  NAME,FAMILY  &  CHEMICAL CONSISTUENTS, USES.

  1. GINKGO BILOBA 8,9
  2. SAW PALMETTO :8,9

Family

Ginkgoaceae

Common Name

Maidenhair Tree

Part Used

Leaves, Seeds

Synonyms

Japanese Silver Apricot

Major Chemical Constituents

Flavonoid glycosides (quercetin, kaempferol), terpenoids

Important Active Compound (IUPAC Name

(1R,2S,3S,6S,7S,9S,10R,11S,14S)-1,10-dihydroxy- 3,7,9,11,14 -pentamethyltricyclo [8.4.0.02

Phytochemical Class

Flavonoids, Terpenoids

Biological / Pharmacological Uses Memory

enhancer, antioxidant, improves blood flow, helps in dementia and Alzheimer’s disease

Pharmacological Actions

Antioxidant, neuroprotective, vasodilator

Dosage (Extract)

120240 mg/day (24% flavone glycosides, 6% terpenoids)

Other Information

Oldest living tree species on Earth

 

PARAMETER

Details

Botanical Name

Serenoa repens (Bartram) Small

Family

Arecaceae

Common Name

Saw Palmetto, Dwarf Palm

Part Use

Dried Ripe Fruit (Berry)

Synonyms

Sabal

Major Chemical Constituents

Fatty acids (lauric, oleic, myristic), phytosterols (β-sitosterol)

Important Active Compound

(3β)-stigmast-5-en-3-ol

Phytochemical Class

Fatty acid sterols

Biological /Pharmacological Uses

UsesUsed in benign prostatic hyperplasia (BPH), urinary tonic

Pharmacological Action

Antiandrogenic, diuretic

Dosage Extract

160 mg twice daily (liposterolic extract)

Other Information

Used for male reproductive health

  1. KAWA KAWA:8,9

PARAMETER

DETAILS

Botanical Name

Piper methysticum Forst

Family

Piperaceae

Ccommon Name

Kava,Ava pepper

Part Used

Rhizome and Roots

Synonyms

Intoxicating Pepper

Major Chemical Constituents

Kavalactones (kavain, methysticin, yangonin, dihydrokavain)

Active Compound

4-methoxy-6-phenyl-2H-pyran-2-one

Phytochemical Class

Kavalactones

Biological /PharmacologicalPharmacological Usee

nxiolytic, sedative, muscle relaxant, mild anesthetic

Pharmacological Action

Anxiolytic, sedative, skeletal muscle relaxant

Dosage Extract

60120 mg kavalactones/day

Other Information

Traditional Polynesian ceremonial drink

Advantages of Herbal Medicine:10

  • They have long history of use and better patient tolerance as well as acceptance.
  • Medicinal plants have a renewable source, which isonly hope for sustainable supplies of cheaper medicines for the world growing population.
  • Availability of medicinal plants is not a problem especially in developing countries like India having rich agro-climatic, cultural and ethnic biodiversity.
  • Prolong and apparently uneventful use of herbal medicines may offer testimony of their safety and efficacy.
  • Throughout the world, herbal medicine has provided many of the most potent medicines to the vast arsenal of drugs available to modern medicinal science, both in crude form and as a pure chemical upon which modern medicines are structured.(12)

Limitations of Herbal Medicines:11

  • Ineffective in acute medical care
  • Inadequate standardization and lack of quality specifications
  • Lack of scientific data

Current & Future Status of Indian Herbal Medicine :

India is sitting on a gold mine of well-recorded and well-practiced knowledge of traditional herbal medicine. India is one of the 12-mega biodiversity centres having over 45,000 plant species. Its diversity is unmatched due to the presence of 16 different agro-climatic zones, 10 vegetative zones and 15 biotic provinces. The country has 15,000–18,000 flowering plants, 23,000 fungi, 2500 algae, 1600 lichens, 1800 bryophytes and 30 million micro-organisms.12

India also has equivalent to 3/4 of its land exclusive economic zone in the ocean harbouring a large variety of flora and fauna, many of them with therapeutic properties. About 1500 plants with medicinal uses are mentioned in ancient texts and around 800 plants have been used in traditional medicine. But, unlike China, India has not been able to capitalize on this herbal wealth by promoting its use in the developed world despite their renewed interest in herbam.13

CONCLUSION :

Herbal medicine continues to play an indispensable role in global healthcare. Its combination of traditional wisdom and modern science holds immense promise for developing safer and more effective therapies. To fully harness its potential, stringent quality control, standardization, and clinical validation are required. With ethical research and sustainable use of plant resources, herbal medicine can offer a bridge between ancient knowledge and future medical innovation.14

REFERENCES

  1. Han Y, Sun H, Zhang A, Yan G, Wang XJ. Chinmedomics, a new strategy for evaluating the therapeutic efficacy of herbal medicines. Pharmacology & therapeutics. 2020 Dec 1; 216:107680.
  2. Liu CX. Overview on development of ASEAN traditional and herbal medicines. Chinese Herbal Medicines. 2021 Oct 1; 13(4):441-50.
  3. Panyod S, Ho CT, Sheen LY. Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective. Journal of traditional and complementary medicine. 2020 Jul 1; 10(4):420-7.
  4. Luo L, Jiang J, Wang C, Fitzgerald M, Hu W, Zhou Y, Zhang H, Chen S. Analysis on herbal medicines utilized for treatmentCurrent and future status of Indian herbal medicines.
  5. Rastogi, P. R. and Meharotra, B. N., In Compendium of Indian Medicinal Plants. Vol. I, 339; III: 194. PID, CSIR, New Delhi, India. , 1990.
  6. Kokate, C.K., Purohit, A.P., Gokhale, S.B. Textbook of Pharmacognosy, Nirali Prakasha
  7. Tyler, V.E., Brady, L.R., Robbers, J.E. Pharmacognosy, Lea & Febiger, Philadelph
  8. C.K. Kokate, A.P. Purohit, S.B. Gokhale. Textbook of Pharmacognosy, Nirali Prakashan.  A standard Indian reference book ideal for undergraduate and diploma pharmacystudents.
  9. World Health Organization. (2021). WHO global report on traditional and complementary medicine 2021. Geneva: WHO.
  10. Harrison, P., Herbal medicine takes roots in Germany. Canadian   Medical  associatedassociation  Journal 10: 637-639, 1998.
  11. Jones, W.B., Alternative medicine-learning from the past examining the present advancing to the future. Journal of American Medical Association 280: 1616-1618, 1998.Medical Association Journal 10: 637-639, 1998.
  12. Hamburger, M. and Hostettmann, K., Bioactivity in plants: the link between phytochemistry and medicine. Phytochemistry 30: 3864-3874, 1991.
  13. Singh, P. and Singh, C. L., Chemical investigations of Clerodendraon fragrans. Journal of Indian Chemical Society 58: 626-627., 1981.
  14. Vinod D. Rangari. Pharmacognosy and Phytochemistry, Career Publications. — Explains pharmacognosy concepts, extraction, and phytochemical analysis clearly.

Reference

  1. Han Y, Sun H, Zhang A, Yan G, Wang XJ. Chinmedomics, a new strategy for evaluating the therapeutic efficacy of herbal medicines. Pharmacology & therapeutics. 2020 Dec 1; 216:107680.
  2. Liu CX. Overview on development of ASEAN traditional and herbal medicines. Chinese Herbal Medicines. 2021 Oct 1; 13(4):441-50.
  3. Panyod S, Ho CT, Sheen LY. Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective. Journal of traditional and complementary medicine. 2020 Jul 1; 10(4):420-7.
  4. Luo L, Jiang J, Wang C, Fitzgerald M, Hu W, Zhou Y, Zhang H, Chen S. Analysis on herbal medicines utilized for treatmentCurrent and future status of Indian herbal medicines.
  5. Rastogi, P. R. and Meharotra, B. N., In Compendium of Indian Medicinal Plants. Vol. I, 339; III: 194. PID, CSIR, New Delhi, India. , 1990.
  6. Kokate, C.K., Purohit, A.P., Gokhale, S.B. Textbook of Pharmacognosy, Nirali Prakasha
  7. Tyler, V.E., Brady, L.R., Robbers, J.E. Pharmacognosy, Lea & Febiger, Philadelph
  8. C.K. Kokate, A.P. Purohit, S.B. Gokhale. Textbook of Pharmacognosy, Nirali Prakashan.  A standard Indian reference book ideal for undergraduate and diploma pharmacystudents.
  9. World Health Organization. (2021). WHO global report on traditional and complementary medicine 2021. Geneva: WHO.
  10. Harrison, P., Herbal medicine takes roots in Germany. Canadian   Medical  associatedassociation  Journal 10: 637-639, 1998.
  11. Jones, W.B., Alternative medicine-learning from the past examining the present advancing to the future. Journal of American Medical Association 280: 1616-1618, 1998.Medical Association Journal 10: 637-639, 1998.
  12. Hamburger, M. and Hostettmann, K., Bioactivity in plants: the link between phytochemistry and medicine. Phytochemistry 30: 3864-3874, 1991.
  13. Singh, P. and Singh, C. L., Chemical investigations of Clerodendraon fragrans. Journal of Indian Chemical Society 58: 626-627., 1981.
  14. Vinod D. Rangari. Pharmacognosy and Phytochemistry, Career Publications. — Explains pharmacognosy concepts, extraction, and phytochemical analysis clearly.

Photo
Digambar Bagul
Corresponding author

Swami Institute of Pharmacy, Abhona, Nashik, Maharashtra, India 423502

Photo
Yashoda Suryawanshi
Co-author

Swami Institute of Pharmacy, Abhona, Nashik, Maharashtra, India 423502

Yashoda Suryawanshi, Digambar Bagul, Review Article of Herbal Medicine, Int. J. of Pharm. Sci., 2025, Vol 3, Issue 12, 304-307. https://doi.org/10.5281/zenodo.17789142

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