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  • Review On Preparation And Evaluation Of Moisturizing Cream
  • Department Of Cosmetic Science Navsahyadri Institute Of Pharmacy Naigaon, Pune, Tal. Bhor, 412213

Abstract

Moisturizing cream are semi solids preparation used for reduces the chances of skin problems and fights wrinkles. The main aim of the research work is to prepare the moisturizing creams using different herbs and the prepared moisturizing cream are evaluated for the efficacy. The herbs used in the preparations are dried Ficus racemose leaves powder and cucumber peels the formulated moisturizing creams are evaluated for the various irritancy, washability, ph, viscosity, phase separation, spread ability, compatibility test. The results shown that all formulation gave satisfied results.

Keywords

cucumber peels, Ficus racemose leaves powder moisturizing cream.

Introduction

Cream is a preparation usually for application to the skin. Creams are defining as "a semisolid dosage form containing one or more drug substances dissolved or dispersed in a suitable base “Creams are semi-solid emulsions of oil and water. O they are of a softer consistency & lighter body than true ointment. Semisolid emulsions of either o/w or w/o type. Moisturizer is a cosmetic preparation used for protecting, moisturizing, and lubricating the skin. These are creams which restore water (moisture) to the stratum corneum.

Water contained in the cream is lost by evaporation when the cream is applied to the body. Moisturizers are complex mixtures of chemical agents often occlusive help hold water in the skin after application, humectants attract moisture and emollients help smooth the skin.

Moisturizer cream is a skincare product used to hydrate and nourish the skin. It typically contains a combination of ingredients that help to increase the water content of the skin and prevent dryness, flakiness, and irritation. Moisturizer cream can be used on the face and body and is available in a range of formulas, including lightweight lotions, thicker creams, and balms. It is an essential component of a skincare routine, as it helps to maintain the skin's natural moisture barrier and improve its overall health and appearance.

CARE FOR DRY SKIN:

During the winter months, it's important to reach for skin care products that contain hydrating and nourishing ingredients that will work hard for your skin to fight the weather's dehydrating effects. Most moisturizers contain a mixture of three groups o Humectants, Emollients, Occlusive.

The cosmetic industry describes the industry that manufactures and distributes cosmetic products. A cosmetic is any substance used to clean, improve or change the complexion, skin, hair, nails or teeth.

Cosmetics include beauty preparations (make-up, perfume, skin cream, nail polish) and shampoo, shaving cream. It is primarily categorized into five major categories - body care, face care, hair care, hand care and colour cosmetics. Cosmetics are the preparations used to enhance the Human appearance.

The aim of the present research was to formulate the Moisturizing Cream for the purpose of Moistening, Nourishing, lightening & Treatment of various diseases of the skin.

Pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients, with the aim to cure them, vaccinate them, or alleviate symptoms. Pharmaceutical companies may deal generic or brand medications and medical devices. To promote high standards in pharmaceutical product production, quality assurance and preparation of compound medicinal prescriptions, pharmaceutical and other appropriate products. (1)

ACTIVE PHARMACUTICAL INGERDIENT INTRODUCTION:

1)   CUCUMBER

Occurrence And Distribution:

Europe, Asia, the Middle East, some parts of the U.S.A.

Taxonomical classification:

Botanical Name: Cucumis sativus Linn.

Local Name: Hindi- Khir Kingdome- Planate Division - Angiosperms Class- Eudicots

Order- Cucurbitales

Family- Cucurbitaceae Subfamily- Cucurbitaceae Genus- Cucumis

Species- C. sativus

Chemical Constituent of Cucumber: Cucumber, scientifically known as Cucumis sativus, contains various active chemical constituents that contribute to its health benefits. Some of the primary active constituents found in cucumber include:

1. Cucurbitacins: These are triterpenes found in cucumber, which have been shown to possess anti-inflammatory and antioxidant properties.

2. Vitamins: Cucumber contains various vitamins, including vitamin C, vitamin K, vitamin B5, and vitamin A, which are important for maintaining good health.

3. Minerals: Cucumber is a good source of minerals, including magnesium, potassium, and manganese, which are essential for various bodily functions.

4. Flavonoids: Cucumber contains flavonoids such as quercetin, apigenin, and kaempferol, which have antioxidant and anti-inflammatory properties

5. Lignans: Cucumber also contains lignans, such as pinoresinol and lariciresinol, which have been shown to have anti-cancer properties.

6. Water: Cucumber is composed mostly of water, which makes it a hydrating food and helps to flush out toxins from the body

These active constituents are responsible for the numerous health benefits associated with cucumber consumption, including improved digestion, reduced inflammation, and enhanced skin health.

USE:

  • Cucumber helps keep the face fresh and glowing, owing to the silica and high-water content.
  • Using cucumber slices on the eyes reduces puffiness and makes dark circles vanish from under the eyes.
  • Do not discard cucumber peel it has many.
  • Health benefits. The benefits include its beneficial.
  • Effects in eye disorders, vitamin A & C deficiency.
  • Constipation and bones and muscles disorder.
  • Cucumber peels are rich in fiber and contain.
  • minerals like magnesium, potassium, and silica.
  • The silica is an essential component to keep your muscles, bones, and tendons healthy.
  • hydrates our skin, improves complexion and vision.(2)

       
            Cucumber.png
       


Pharmacological activity: Cucumbers have several pharmacological activities that are beneficial to human health. Some of these activities include:

1. Antioxidant activity: Cucumbers are a good source of antioxidants such as vitamin C and beta-carotene, which can help protect cells from damage caused by free radicals.

2.  Anti-inflammatory activity: Cucumbers contain compounds such as cucurbitacins and flavonoids, which have anti-inflammatory properties. These compounds may help reduce inflammation in the body and alleviate symptoms of conditions such as arthritis.

3. Anti-cancer activity: Some studies suggest that cucumbers may have anti-cancer properties due to their high antioxidant content and ability to reduce inflammation.

4. Skin health activity: Cucumbers contain vitamins and minerals that are beneficial for skin health. For example, vitamin C can help promote collagen production, while silica can help strengthen connective tissues in the skin.

Overall, cucumbers are a nutritious and healthy food that can provide several pharmacological benefits. (3,4,5,6)

2) FICUS RACEMOSA

TAXONOMY

Kingdom: Plant Family

Classification: Magnoliophyta

Class: Magnolipsida

Order: Urticales

Family: Moraceae

Genus: Ficus

Species: racemosa.

Synonyms: - F. glomerata Roxb (7)

Chemical Constituent of ficus racemosa

Ficus recemosa, also known as the cluster fig tree, is a species of plant in the fig family. It has several active chemical constituents, including:

1. Ficusin - a flavonoid with anti-inflammatory properties.

2. Lupeol - a triterpenoid with anti-inflammatory and anti-cancer properties.

3. Psoralen - a furanocoumarin with anti-inflammatory and antioxidant properties.

4. Bergapten - a furanocoumarin with antioxidant and anti-inflammatory properties.

5. Quercetin - a flavonoid with antioxidant, anti-inflammatory, and anti-cancer properties.

6. Luteolin - a flavonoid with antioxidant, anti-inflammatory, and anti-cancer properties.

7. Kaempferol - a flavonoid with antioxidant, anti-inflammatory, and anti-cancer properties.

8. ?-sitosterol - a phytosterol with cholesterol-lowering properties.

These active chemical constituents have been studied for their potential therapeutic benefits and may have applications in the treatment of various diseases and disorders. However, further

research is needed to fully understand their mechanisms of action and potential clinical uses. (8,9,10)


       
            132.png
       


  1. Anti-inflammatory activity: The ethanolic extract of Ficus racemosa has been found to possess anti-inflammatory activity in animal models. This activity is believed to be due to the presence of flavonoids, tannins, and other bioactive compounds.
  2. Antioxidant activity: Ficus racemosa is known to possess potent antioxidant activity due to the presence of phenolic compounds and flavonoids. These compounds scavenge free radicals and protect against oxidative damage.
  3. Anti-cancer activity: Ficus racemosa has been reported to possess anti-cancer properties, particularly against breast cancer cells. The plant extract has been shown to induce cell death and inhibit the proliferation of cancer cells.
  4. Wound healing activity

Stem bark ethanol extract showed healing in rat excision and incision wound models

  1. Antifungal

Plants showed potent inhibitory activity against six fungi. Trichophyton mentagrophytes, Trichophyton rubrum, Trichophyton vocalis, Candida albicans, Candida cruzi and Torulopsis glabrata (11,12,13,14,15)


       
            Formula.png
       

Formula:


       
            ROLE OF INGREDIENTS.png
       

ROLE OF INGREDIENTS


REFERENCES

  1. https://www.slideshare.net/Ayanpal33/moisturizing-cream-ppt
  2. Tripti Sahu*, Jyoti SahuISSN No. 2348 – 0335Journal of Applied Pharmaceutical Researchwww.japtronline.com.
  3. HinaSaeed, AnamWaheedISSN No.: 2454- 2024 (online)International Journal of Technical Research & Science.
  4. Tripathi KD, “Essentials of Medical Pharmacology”, 6th edition, Jaypee Brothers Medical, New Delhi, 2008, 185.
  5. Rang HP, Dale MM, “Pharmacology”, 6th Edition, Churchill Livingstone Elsevier, 2007, 502-3
  6. Ankita S., Kaur P., and Gupta R. Phytochemical screening and antimicrobial assay of various seeds extracts of Cucurbitaceae Family. International Journal of Applied Biology & Pharmaceutical Technology. Volume 3, Issue 3 (2012): 401-409
  7. Sasaki YF, Kawaguchi S, Kamaya A, Ohshita M, Kabasawa K, Iwama K et al. 2002 Mutation Research/Genetic Toxicology and Environmental Mutagenesis.; 519(1):103- 119.
  8. Cai Y, Luo Q, Sun M, Corke H. Life Sci.2004; 74(171):2157-2184.Antioxidant activity and phenolic compounds of 112 traditional Chinese meditional plants associated with anticancer.
  9. Sumi SA, Siraj MA, Hossain A, Mia MS, Afrin S,Rahman MM. Med. 2016 Investigation of the Key Pharmacological Activities of Ficus racemosa and Analysis of Its Major Bioactive Polyphenols by HPLC-DAD. Evidence-Based Complement. Altern.
  10. Prakash Deep, Amrit Kr. Singh, Md. Tahir Ansari, Prashant Raghav, Sep – Oct 2013; Int. J. Pharm. Sci. Rev. Res., 22(1), n? 06, 29-34 ISSN 0976 – 044X
  11. IJCRT1813121 International Journal of Creative Research Thoughts (IJCRT) www.ijcrt.org
  12. Biswas TK, Mukherjee B, Plant medicines of Indian origin for wound healing activity: a review. Int J Low Extreme Wounds, 2, 2003, 25- 39.
  13. Deraniyagala SA, Wijesundera RLC, Weerasena OVD, Antifungal activity of Ficus racemosa leaf extract and isolation of the active compound, J Nat Sci Counc Sri Lanka, 26, 1998, 19-26.
  14. ISSN: 1388-0209 (Print) 1744-5116 (Online) Journal homepage: https://www.tandfonline.com/loi/iphb20
  15. https://www.researchgate.net/publication/330956326
  16. https://chat.openai.com/?model=text-davinci-002-render
  17. A.U. Adamu, Y. Abdulmumin, RK Mustapha, J. Mater.Environ. Sci., 2021, Volume 12, Issue 12, Page 1627-1636, Journal of Materials and Environmental Science ISSN: 2028-2508CODEN: JMESCN, http://www.jmaterenvironsci.com
  18. Sunil H. Ganatra, Shweta P. Durge, Patil S. U., ISSN : 0975-7384CODEN(USA)

:JCPRC5, Journal of Chemical and Pharmaceutical Research,2012,4(5):2380-2384 , www.jocpr.com

  1. Dr. Supriya Yadav, Dr. VK Gupta, Dr. A Gopalakrishnan and Dr. Med Ram Verma, Journal of Entomology and Zoology Studies 2019; 7(1): 1443-1446
  2. Bhavana Patil, Neha Yadav, Gopal Yadav, Shrikesh Yadav, Suraj Yadav,Dr. Smita Takarkhede© 2022 JETIR March 2022, Volume 9, Issue 3www.jetir.org (ISSN-2349- 5162)

Reference

  1. https://www.slideshare.net/Ayanpal33/moisturizing-cream-ppt
  2. Tripti Sahu*, Jyoti SahuISSN No. 2348 – 0335Journal of Applied Pharmaceutical Researchwww.japtronline.com.
  3. HinaSaeed, AnamWaheedISSN No.: 2454- 2024 (online)International Journal of Technical Research & Science.
  4. Tripathi KD, “Essentials of Medical Pharmacology”, 6th edition, Jaypee Brothers Medical, New Delhi, 2008, 185.
  5. Rang HP, Dale MM, “Pharmacology”, 6th Edition, Churchill Livingstone Elsevier, 2007, 502-3
  6. Ankita S., Kaur P., and Gupta R. Phytochemical screening and antimicrobial assay of various seeds extracts of Cucurbitaceae Family. International Journal of Applied Biology & Pharmaceutical Technology. Volume 3, Issue 3 (2012): 401-409
  7. Sasaki YF, Kawaguchi S, Kamaya A, Ohshita M, Kabasawa K, Iwama K et al. 2002 Mutation Research/Genetic Toxicology and Environmental Mutagenesis.; 519(1):103- 119.
  8. Cai Y, Luo Q, Sun M, Corke H. Life Sci.2004; 74(171):2157-2184.Antioxidant activity and phenolic compounds of 112 traditional Chinese meditional plants associated with anticancer.
  9. Sumi SA, Siraj MA, Hossain A, Mia MS, Afrin S,Rahman MM. Med. 2016 Investigation of the Key Pharmacological Activities of Ficus racemosa and Analysis of Its Major Bioactive Polyphenols by HPLC-DAD. Evidence-Based Complement. Altern.
  10. Prakash Deep, Amrit Kr. Singh, Md. Tahir Ansari, Prashant Raghav, Sep – Oct 2013; Int. J. Pharm. Sci. Rev. Res., 22(1), n? 06, 29-34 ISSN 0976 – 044X
  11. IJCRT1813121 International Journal of Creative Research Thoughts (IJCRT) www.ijcrt.org
  12. Biswas TK, Mukherjee B, Plant medicines of Indian origin for wound healing activity: a review. Int J Low Extreme Wounds, 2, 2003, 25- 39.
  13. Deraniyagala SA, Wijesundera RLC, Weerasena OVD, Antifungal activity of Ficus racemosa leaf extract and isolation of the active compound, J Nat Sci Counc Sri Lanka, 26, 1998, 19-26.
  14. ISSN: 1388-0209 (Print) 1744-5116 (Online) Journal homepage: https://www.tandfonline.com/loi/iphb20
  15. https://www.researchgate.net/publication/330956326
  16. https://chat.openai.com/?model=text-davinci-002-render
  17. A.U. Adamu, Y. Abdulmumin, RK Mustapha, J. Mater.Environ. Sci., 2021, Volume 12, Issue 12, Page 1627-1636, Journal of Materials and Environmental Science ISSN: 2028-2508CODEN: JMESCN, http://www.jmaterenvironsci.com
  18. Sunil H. Ganatra, Shweta P. Durge, Patil S. U., ISSN : 0975-7384CODEN(USA)

:JCPRC5, Journal of Chemical and Pharmaceutical Research,2012,4(5):2380-2384 , www.jocpr.com

  1. Dr. Supriya Yadav, Dr. VK Gupta, Dr. A Gopalakrishnan and Dr. Med Ram Verma, Journal of Entomology and Zoology Studies 2019; 7(1): 1443-1446
  2. Bhavana Patil, Neha Yadav, Gopal Yadav, Shrikesh Yadav, Suraj Yadav,Dr. Smita Takarkhede© 2022 JETIR March 2022, Volume 9, Issue 3www.jetir.org (ISSN-2349- 5162)

Photo
Kiran Gokul Khandekar
Corresponding author

Department Of Cosmetic Science Navsahyadri Institute Of Pharmacy Naigaon, Pune, Tal. Bhor, 412213

Photo
Rahul Jagtap
Co-author

Department Of Cosmetic Science Navsahyadri Institute Of Pharmacy Naigaon, Pune, Tal. Bhor, 412213

Kiran Gokul khandekar, Rahul Jagtap, Review On Preparation And Evaluation Of Moisturizing Cream, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 6, 363-368. https://doi.org/10.5281/zenodo.11506311

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