Archive

Abstract

The 21st century is a challenge for people. Population growth, aging population, generation of new infectious agents, and natural disasters are some of the factors that threaten the status quo of blood transfusions. Artificial blood is designed solely to carry oxygen and carbon dioxide into the body. Depending on the type of blood replacer, it can be produced with a variety of techniques using chemical separation, synthetic production, or recombinant biochemical techniques. The technologies focused on the two major alternatives to blood are perfluorocarbons and hemoglobin-based oxygen carriers (HBOCs). With the availability of blood products, the United States alone is expected to generate more than $ 7.6 billion annually.

Keywords

artificial blood, hemoglobin, hemoglobinbased oxygen carriers, oxygen carrier, Perfluorocarbons, red blood cells

Reference

  1. Suman Sarkar, Artificial Blood, Indian Journal Of Critical Care Medicine,  2008 Jul-Sep; 12(3): 140–144.
  2. Pacific Heart, Lung & Blood Institute, Artificial Blood Substitutes, A 501(C)(3) 
  3. Keyhanian Sh Phd1 ,Ebrahim ifard M Msc, ,Zandi M Msc3, Investigation On Artificial Blood Or Substitute Blood Replace The Natural Blood, Iranian Journal Of Pediatric Hematology Oncology Vol4.No2.
  4. Samira Moradi, Ali Jahanian-Najafabadi, Mehryar Habibi Roudkenar, Artificial Blood Substitutes: First Steps On The Long Route To Clinical Utility, Clinical Medicine  Insights Blood Disord. 2016; 9: 33–41.
  5. Mayurya Krishna, Khatoon Ruqsana, Paswan Shravan, Artificial Blood: A Tool For Survival Of Human, International Research Journal Of Pharmacy, 3(5) : 119-123, May 2012.
  6. Robert M. Winslow,How To Scientists Makes Artificial Blood ? How Effective Is It Compared With Real Things, Octomber 21,1999
  7. Dr Izzuna Mudla Bt Mohamed Ghazali, Dr Mohd Aminuddin Bin Mohd Yusof , Health Technology Assessment Unit Medical Development Division Ministry Of Health Malaysia 008/07, Journal Of American College Of Surgeons. 2003;196(1): Pg 8.
  8. Masoud Mozafari1*, Arash Ramedani2 And Aboulfazl Yazdanpanah3, Artificial Blood- A Game Changer Of Future Medicine, Journal Of Blood Disorders And Transfusion, Volume 6, Issue 5. 
  9. Jiin-Yu Chen, Michelle Scerbo, George Kramer, A Review Of Blood Substitutes: Examining The History, Clinical Trial Results, And Ethics Of Hemoglobin-Based Oxygen Carriers 2009 Aug; 64(8): 803–813. 
  10. Winslow Rm. Hemoglobin-Based Red Cell Substitutes. Baltimore And London: Johns Hopkins University Press; 1992. The Results Of 62 Large-Volume Hemoglobin Infusions In Man; Pp. 177–8. 
  11. Krishna Veni R, Brindha Devi P, Ivo Romauld S, A Review On Artificial Blood: A Source We Need, Asian Journal Of Pharmaceutical And Clinical Research,  Vol 10, Issue 9, 2017.
  12. Shinji Takeoka, Developmental Trend Of Artificial Blood ( Artificial Red Blood Cell), Journal Of The Japan Medical Association ,Vol. 131, No. 7, 2004, Pages 907–910.
  13. Trevor Bernier, Biomedical Engineering, University of Rhode Island BME 281 First Presentation, artificial blood, November 26, 2012
  14. L. Mohankrishna, G.Balammal, G.Aruna, A Review On Artificial Blood, International Journal Of Biopharmaceutics, 2011; 2(2): 80-88

Photo
Rajnandini Ahire
Corresponding author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Photo
Mukesh Ratnaparkhi
Co-author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Photo
Shital Kshirsagar
Co-author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Photo
Devang Mahale
Co-author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Rajnandini Ahire, An Overview on Artificial Blood, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 1, 42-47. https://doi.org/10.5281/zenodo.5655215

More related articles
Review Article on Oral Controlled Released Trans-m...
Sayyed ahamad Sayyed Kaleem , Quazi Majaz, Hamza Ilyas, Shah Afri...
Lifestyle Medicine Encompassing Scientific Exercis...
J.C Balachandar, S. Irshad Ahamed, Amit Kumar Agrawal, Baani Khan...
A Review On Medicinal Importance Of Tridax Procumb...
Monali S. Ghuge, Nikita K. Andhale, Sonali S. Ghuge, ...
A Review on Various Analytical Methodologies for Buspirone...
Vikas R. Patil, Vinay V. Sarode, Samir B. Tadvi, Bhushan P. Patil, Vaishali Badgujar, ...
A Review On Suppositories...
N Deekshitha Reddy , K. Muniraja Lakshmi, ...
Review On Self Micro Emulsifying Drug Delivery System SMEDDS...
Jadhav Bharat V., Tattu Arpita B., Jadhav Supriya B., Bade urmila R., ...
Related Articles
A Review On Application And Scopes For Dosage Forms Of Cissus Quadrangularis Ext...
Rohit R. Eklare, Mahesh M. Biradar, Anita S. Chavan, Vaishnavi K. Chavhan, Anjali G. Chopade, ...
A study of challenges and quality of life QoL issues related to Vitiligo disease...
Yash Srivastav, Akhandnath Prajapati, Adityanath Prajapati, Madhaw Kumar, Mohammad Aqil Siddiqui, ...
The Skin Battle: Exploring The Depths Of Pyoderma Diagnosis, Treatment, And Mana...
Thayana Ramasamy, Shavitha Jayaseelan, Gokulalakshmi Moorthy, Madhu Midha Muruganantham, ...
Review Article on Oral Controlled Released Trans-mucosal Delivery’s System for...
Sayyed ahamad Sayyed Kaleem , Quazi Majaz, Hamza Ilyas, Shah Afrin Salim, Shaikh Amaan Zahid, ...
More related articles
Review Article on Oral Controlled Released Trans-mucosal Delivery’s System for...
Sayyed ahamad Sayyed Kaleem , Quazi Majaz, Hamza Ilyas, Shah Afrin Salim, Shaikh Amaan Zahid, ...
Lifestyle Medicine Encompassing Scientific Exercises and Right Diet The Key To P...
J.C Balachandar, S. Irshad Ahamed, Amit Kumar Agrawal, Baani Khanna, Dilsher Khanna, M. Jayachandran...
A Review On Medicinal Importance Of Tridax Procumbens Linn ...
Monali S. Ghuge, Nikita K. Andhale, Sonali S. Ghuge, ...
Review Article on Oral Controlled Released Trans-mucosal Delivery’s System for...
Sayyed ahamad Sayyed Kaleem , Quazi Majaz, Hamza Ilyas, Shah Afrin Salim, Shaikh Amaan Zahid, ...
Lifestyle Medicine Encompassing Scientific Exercises and Right Diet The Key To P...
J.C Balachandar, S. Irshad Ahamed, Amit Kumar Agrawal, Baani Khanna, Dilsher Khanna, M. Jayachandran...
A Review On Medicinal Importance Of Tridax Procumbens Linn ...
Monali S. Ghuge, Nikita K. Andhale, Sonali S. Ghuge, ...