View Article

Abstract

The 21st century is a challenge for people. Population growth, aging population, generation of new infectious agents, and natural disasters are some of the factors that threaten the status quo of blood transfusions. Artificial blood is designed solely to carry oxygen and carbon dioxide into the body. Depending on the type of blood replacer, it can be produced with a variety of techniques using chemical separation, synthetic production, or recombinant biochemical techniques. The technologies focused on the two major alternatives to blood are perfluorocarbons and hemoglobin-based oxygen carriers (HBOCs). With the availability of blood products, the United States alone is expected to generate more than $ 7.6 billion annually.

Keywords

artificial blood, hemoglobin, hemoglobinbased oxygen carriers, oxygen carrier, Perfluorocarbons, red blood cells

Reference

  1. Suman Sarkar, Artificial Blood, Indian Journal Of Critical Care Medicine,  2008 Jul-Sep; 12(3): 140–144.
  2. Pacific Heart, Lung & Blood Institute, Artificial Blood Substitutes, A 501(C)(3) 
  3. Keyhanian Sh Phd1 ,Ebrahim ifard M Msc, ,Zandi M Msc3, Investigation On Artificial Blood Or Substitute Blood Replace The Natural Blood, Iranian Journal Of Pediatric Hematology Oncology Vol4.No2.
  4. Samira Moradi, Ali Jahanian-Najafabadi, Mehryar Habibi Roudkenar, Artificial Blood Substitutes: First Steps On The Long Route To Clinical Utility, Clinical Medicine  Insights Blood Disord. 2016; 9: 33–41.
  5. Mayurya Krishna, Khatoon Ruqsana, Paswan Shravan, Artificial Blood: A Tool For Survival Of Human, International Research Journal Of Pharmacy, 3(5) : 119-123, May 2012.
  6. Robert M. Winslow,How To Scientists Makes Artificial Blood ? How Effective Is It Compared With Real Things, Octomber 21,1999
  7. Dr Izzuna Mudla Bt Mohamed Ghazali, Dr Mohd Aminuddin Bin Mohd Yusof , Health Technology Assessment Unit Medical Development Division Ministry Of Health Malaysia 008/07, Journal Of American College Of Surgeons. 2003;196(1): Pg 8.
  8. Masoud Mozafari1*, Arash Ramedani2 And Aboulfazl Yazdanpanah3, Artificial Blood- A Game Changer Of Future Medicine, Journal Of Blood Disorders And Transfusion, Volume 6, Issue 5. 
  9. Jiin-Yu Chen, Michelle Scerbo, George Kramer, A Review Of Blood Substitutes: Examining The History, Clinical Trial Results, And Ethics Of Hemoglobin-Based Oxygen Carriers 2009 Aug; 64(8): 803–813. 
  10. Winslow Rm. Hemoglobin-Based Red Cell Substitutes. Baltimore And London: Johns Hopkins University Press; 1992. The Results Of 62 Large-Volume Hemoglobin Infusions In Man; Pp. 177–8. 
  11. Krishna Veni R, Brindha Devi P, Ivo Romauld S, A Review On Artificial Blood: A Source We Need, Asian Journal Of Pharmaceutical And Clinical Research,  Vol 10, Issue 9, 2017.
  12. Shinji Takeoka, Developmental Trend Of Artificial Blood ( Artificial Red Blood Cell), Journal Of The Japan Medical Association ,Vol. 131, No. 7, 2004, Pages 907–910.
  13. Trevor Bernier, Biomedical Engineering, University of Rhode Island BME 281 First Presentation, artificial blood, November 26, 2012
  14. L. Mohankrishna, G.Balammal, G.Aruna, A Review On Artificial Blood, International Journal Of Biopharmaceutics, 2011; 2(2): 80-88

Photo
Rajnandini Ahire
Corresponding author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Photo
Devang Mahale
Co-author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Photo
Mukesh Ratnaparkhi
Co-author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Photo
Shital Kshirsagar
Co-author

Department of Pharmaceutics, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune411033, Maharashtra, India

Rajnandini Ahire, An Overview on Artificial Blood, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 1, 42-47. https://doi.org/10.5281/zenodo.5655215

More related articles
Neuroprotective and Antioxidant Effect of Naringen...
Chandrakor Patil, Manoj Jaybhaye, Monika Jangid, Shrutika More, V...
A Review Article on Aging and Age-Related Disorder...
Sudarsanam Nagarjuna, Sk. Naziya, S. Mohan, M. Beula, Leishangthe...
Knowledge, Attitudes, and Practice Regarding Period-Delay Medicines and Self Rep...
Zainab Mollick, Bijalee Moirangthem, Bogom Jai, Olivia Lambalmayum, Vidyashree BH...
Role of Regulatory Affairs in the Pharmaceutical Industry: Functions and Career ...
Puneet Vinod Kumar Pandey, Aditya Ram, Rohit Kumar, Vaishali Pawar, Tejaswini Asawe...
Formulation, Optimization and Evaluation of Antibacterial Nanoparticle-Loaded in...
Kadeeja Ps, Sajin K. C., Greeshma V. P., Geetha V. S., Afeefa K. A....
Related Articles
Design Prepare and in Vitro Evaluation of Solid Lipid Nanoparticles Loaded Deoxy...
P. V. Pavan Kumar, Sazeeda, S. Swetha, S. Sudarshan, S. Charani, S. Alekhya...
Formulation and Invitro Evaluation of Gentamicin Transfersomal Gel...
D. Usha Rani, T. Keerthana, S. Shiva Kumar Reddy, S. Shiva Kumar, S. Niharika...
Formulation and Evaluation of Mango Leaf Extract Loaded Phytosomes for Enhanced ...
P. V. Pavan Kumar, B. Saikiran, B. Harika, A. Pavan Kumar...
Neuroprotective and Antioxidant Effect of Naringenin-Loaded Nanoparticles for No...
Chandrakor Patil, Manoj Jaybhaye, Monika Jangid, Shrutika More, Vaibhav Sakhare, Dhanshri Kalsai...
More related articles
Neuroprotective and Antioxidant Effect of Naringenin-Loaded Nanoparticles for No...
Chandrakor Patil, Manoj Jaybhaye, Monika Jangid, Shrutika More, Vaibhav Sakhare, Dhanshri Kalsai...
A Review Article on Aging and Age-Related Disorders...
Sudarsanam Nagarjuna, Sk. Naziya, S. Mohan, M. Beula, Leishangthem. Dibiya Devi, K. Sravani, K. Prav...
Neuroprotective and Antioxidant Effect of Naringenin-Loaded Nanoparticles for No...
Chandrakor Patil, Manoj Jaybhaye, Monika Jangid, Shrutika More, Vaibhav Sakhare, Dhanshri Kalsai...
A Review Article on Aging and Age-Related Disorders...
Sudarsanam Nagarjuna, Sk. Naziya, S. Mohan, M. Beula, Leishangthem. Dibiya Devi, K. Sravani, K. Prav...