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Abstract

In these studies, Dapagliflozin action was seen in different disease conditions like Diabetes mellitus, Heart failure, and Renal failure. The class of Dapagliflozin is sodium-glucose cotransporter 2 inhibitors, it shows major action in the kidneys. it blocks the reabsorption of filtered glucose in the kidney, increases urinary glucose excretion, and reduces blood glucose levels. by this mechanism, it maintains the blood glucose level and excretes the excess amount of water through urine. Dapagliflozin is used in the treatment of reduced ejection fraction in heart failure patients for better improvement in the condition. In renal failure also these drugs are used for the improvement in the excretion of urine.

Keywords

Dapagliflozin, Diabetes Mellitus, Heart failure, Renal failure, Sodium glucose cotransporter 2 inhibitor

Reference

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P. Shaheera
Corresponding author

Department of Pharmacy Practice, Hindu College of Pharmacy, Guntur -522002, Andhra Pradesh, India.

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G. Anjani Tejaswi
Co-author

Department of Pharmacy Practice, Hindu College of Pharmacy, Guntur -522002, Andhra Pradesh, India.

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A. Navyasree
Co-author

Department of Pharmacy Practice, Hindu College of Pharmacy, Guntur -522002, Andhra Pradesh, India.

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M. Bala Tripur Sundari
Co-author

Department of Pharmacy Practice, Hindu College of Pharmacy, Guntur -522002, Andhra Pradesh, India.

Photo
P. Seetharamaiah
Co-author

Department of Pharmacy Practice, Hindu College of Pharmacy, Guntur -522002, Andhra Pradesh, India.

P. Shaheera, G. Anjani Tejaswi, A. Navyasree, M. Bala Tripur Sundari, P. Seetharamaiah, A Review of Dapagliflozin Effect On Disease Conditions Like Diabetes Mellitus, Heart Failure, Renal Failure, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 9, 71-76. https://doi.org/10.5281/zenodo.8322377

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