Sri Venkateswara College of Pharmaceutical Sciences, S V University, Tirupati
Nanotechnology is the study of manipulating matter at the atomic and molecular levels and deals with matter at a scale of 1 billionth of a metre. The quality of human life recently been altered and improved physically using particulate systems like nanoparticles. They have been used in vivo to maintain the drug entity in systemic circulation, prevent drug access to the targeted sites, and transport the drug to the site of action at a controlled and steady rate. In general, nanoparticles have one or more dimensions and range in size from 1 to 100 nm. Nanoparticles are the preparations having size in nanometres. In this various polymer are used in the formulation of nanoparticles for the drug delivery research to increase therapeutic benefit. This review mainly focussed on types, preparation methods such as cross-linking technique, polymerization-based methods, polymer precipitation methods, and evaluation parameters such as particle size, zeta-potential, particle shape, drug entrapment efficiency, scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, differential scanning calorimetry, surface hydrophobicity, invitro drug release of nanoparticles.
Muni Raja Lakshmi K*, Lavanya E, Naseema Shaik, Vankata Rao Gadde, Formulation And Evaluation of Nanoparticles-A Review, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 7, 196-204. https://doi.org/10.5281/zenodo.8127920