1Department of Pharmaceutics, R. G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213
2Department of Pharmacology, R. G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213
The aim of this work was to plan mucoadhesive bilayered buccal tablets of Sitagliptin Phosphate. Sitagliptin Phosphate is the phosphate salt type of sitagliptin, an orally accessible, serious, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP4) with hypoglycemic movement. Sitagliptin might cause an expanded danger in the advancement of pancreatitis. Mucoadhesive polymers like thickener and guar gum alongside methyl crystalline cellulose were utilized for the development of mucoadhesive bilayered tablets. The upgraded plan followed Non-Fickian discharge system. The rate relative bioavailability of Sitagliptin Phosphate from chose bilayered buccal tablets was viewed as 98.7%. Bilayered buccal tablets of Sitagliptin Phosphate was effectively ready and assessed with further developed bioavailability.
Mayur aware, Sheetal gondkar, Rishikesh bachhav, Formulation And In-vitro Evaluation Of Bilayer Tablets Of Sitagliptin Phosphate, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 2, 49-61. https://doi.org/10.5281/zenodo.5778984