Green Nanotechnology using Ayurvedic Herbs

Abstract

Green nanotechnology employs phytochemicals found in plants to produce eco-friendly nanoparticles without the use of hazardous materials. Some of the herbal medicines that possess active principles like flavonoids, alkaloids, polyphenols found in Tulsi, Neem, Turmeric, Ashwagandha, and Guduchi can be used as reducing agents for nanoparticle production. Herbal nanoparticles provide better bioavailability, targeted delivery, and therapeutic effectiveness of herbal medicines. This paper focuses on the process of green nanotechnology, herbal nanotechnology forms, the benefits of herbal nanotechnology, recent herbal formulations of Ayurvedic medicines using nanotechnology, along with differences between herbal medicines

Keywords

Green nanotechnology; Ayurvedic herbs; Herbal nanomedicine; Plant-mediated nanoparticle synthesis; Phytochemicals; Silver nanoparticles; Gold nanoparticles; Nano-curcumin; Herbal nanoformulations; Eco-friendly synthesis

Introduction

Challenges in Herbal Nanotechnology:

• Lack of Standardization
• Scale-up issues
• Uncertainty related to
• Few long-term toxicity tests:
• Variability in Plant Extract Composition

Future Scope:

• AI Optimization of Green Synthesis
• Multi-herbal nano formulations
• Clinical trials of the Ayurvedic Nano Drugs
• Nanotechnology-based Ayurvedic Cosmeceuticals
• Smart (pH/temperature/enzyme-responsive) nano-herbal systems

CONCLUSION:

Green nanotechnology is an area that is gaining importance for the development of herbal nanomedicine by merging herbal therapeutics with nanotechnology. Utilization of herbal extracts as biologic reducing and stabilizing agents helps in synthesizing biodegradable nanoparticles with improved bioavailability, therapeutic potency, and low cytotoxicity. Green nanotechnology synthesized nanoparticles exhibit excellent biocompatibility with significant properties in drug delivery systems, antimicrobial, antioxidant, anti-inflammatory, and cancer applications, with better biocompatibility compared with their chemical counterparts.

Despite such benefits, issues such as batch variability, non-standardization, limited in vivo & clinical data, and regulatory issues should be attended to. Future studies should emphasis on understanding, mass production, toxicological analysis, and subsequent validation of Green nanotechnology applications for the development of herbal drugs. Conclusion: Green nanotechnology is a safe, low-cost, eco-friendly technology for the development of herbal delivery systems.

RESULTS AND DISCUSSION:

The recent studies reveal that green nanotechnology using herbal extracts is quite an efficient and eco-friendly method of nanoparticle synthesis. Phytochemicals like flavonoids, phenolics, alkaloids, terpenoids, and proteins in medicinal plants act as reducing, capping agents, and stabilizers simultaneously without the usage of toxic chemicals.

The synthesized herbal nanoparticles normally exhibit uniform size distribution, stability, and increased surface reactivity. Green-synthesized nanoparticles, compared to conventionally synthesised NPs, have less toxicity and more biocompatibility.

The nano-formulation in herbal medicine delivery significantly improves the solubility, bioavailability, and therapeutic efficacy of plant-based drugs. Increased cellular uptake and sustained drug release have been consistently reported to enhance antimicrobial, antioxidant, anti-inflammatory, and anticancer activities.

Overall, the findings are that GNT provides a cost-effective, eco-friendly, and biologically safer platform to modernize herbal medicine. However, variability in plant composition and limited clinical studies remain challenges, hence requiring standardization and in vivo validation.

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