1Assistant Professor, Department of Pharmaceutics, Smt. B.N.B Swaminarayan Pharmacy, Salvav-Vapi
2Assistant Professor, Department of Pharmaceutical Quality Assurance, Smt. B.N.B Swaminarayan Pharmacy, Salvav-Vapi
3Assistant Professor, Department of Pharmaceutical Quality Assurance, Smt. B.N.B Swaminarayan Pharmacy, Salvav-Vapi
4Assistant Professor, Department of Pharmaceutical Quality Assurance, Smt. B.N.B Swaminarayan Pharmacy, Salvav-Vapi
The majority of the novel medication candidates are lipophilic and water-insoluble. The pharmaceutical industry has a tremendous difficulty in improving the solubility and bioavailability of these medications. The Liquisolid technique, which involves converting a liquid medicine into a seemingly dry, non-adherent, free-flowing, and compressible powder, is an innovative and sophisticated method for dealing with the problem. The purpose of this article is to provide an overview of the Liquisolid technology as well as a summary of its advancement in pharmaceutics. The key advantages of this technology are its low cost, easy processing, and large industrial production capacity. This approach is a relatively recent technique for efficiently retarding drug release, in addition to improving the dissolving rate of weakly water-soluble medicines. In addition, the Liquisolid approach has been examined as a tool for reducing the impact of pH variations on drug release and as a possible alternative to traditional coating for improving drug photostability in solid dosage forms. Overall, the Liquisolid approach is a new and promising tool for improving drug dissolving and extending drug release, and its pharmaceutics applications are currently being explored.
Desai Avni P., Krishna P. Vairagi, Dhruvi B. Parmar, Heli H. Desai, Overview On The Novel Medication Of Liquisolid Technology For Improving Solubility And Bioavailability, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 8, 169-185. https://doi.org/10.5281/zenodo.8262407