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Abstract

Tridax procumbens, or coat buttons, is an significant medicinal plant, primarily found in southern and central America.. It is a member of the Asteraceae family. All around the world, it grows well in tropical, subtropical, and mildly temperate climates.This flowering plant, recognized as a widespread weed, boasts numerous medicinal properties. The entire plant extract serves as a valuable drug, with Tridax procumbens being utilized for its antidiabetic, antioxidant, hepato-protective, and wound-healing attributes. Additionally, it aids in the management of kidney stone disease, liver problems, and infectious skin infections. Flavonoids, alkaloids, saponins, tannins, terpenes, kaempferol, and isoquercetin are some of the plant's main active ingredients. It has historically been used to treat conditions like gastritis, blisters, ulcers, jaundice, and respiratory disorders.

Keywords

Tridax procumbens pharmacology, composition, microbial, phytochemical, plant.

Reference

  1. Kondawar VB. A comprehensive review on phytochemistry and pharmacological use of Tridax procumbens Linn. Journal of Pharmacognosy and Phytochemistry. 2019;8(4):01-10.
  2. Ghosh P, Biswas S, Biswas M, Dutta A, Sil S, Chatterjee S. Morphological, Ethno biological and Phytopharmacological Attributes of Tridax procumbens Linn.(Asteraceae): A Review. Int. J. Sci. Res. in Biological Sciences Vol. 2019 Apr;6:2.
  3. Bhagwat D A, Killedar S G, Adnaik R S. Anti-diabetic activity of leaf extract of Tridax procumbens, International Journal of Green Pharmacy, 2008, 126-128.
  4. Wani Minal, Pande Snehal, More Nitin. Callus induction studies in Tridax procumbens L." International Journal of Biotechnology Applications. 2010; 2(1):11–4.
  5. Nallella, Sreeramulu et al. Ethno-botanico-medicine for common human ailments in Nalgonda and Warangal districts of Telangana, Andhra Pradesh, India". Annals of Plant Sciences. 2013; 2(7):220-9
  6. Chitra pai antibacterial activity of tridax procumbens with special reference to nosocomial pathogens british journal of pharmaceutical research 1(4):164-173,2011.
  7. wikipedia.org
  8. Gadre A and Gabhe SY (1992). Identification of some sterols of Tridax procumbens by GC-MS. Indian J. Pharm. Scien., 55(5): 191-192.
  9. Ali MS and Jahangir M (2002). A Bis-Bithiophene from Tridax procumbens L. (Asteraceae). Nat. Prod. Res., 16(4): 217-221
  10. Ali ME and Ramachandram R (2001). A new flavonoid from the aerial parts of Tridax procumbens. Fitoterapia, 72(3): 313-315.
  11. Verma RK and Gupta MM (2004). Lipid constituents of Tridax procumbens. Indian Drugs, 30(2): 64-69.
  12. https://images.app.goo.gl/9LigyKfiMcviKLWB9
  13. Caceres, A., López, B., González, S., Berger, I.,Tada, I., Maki, J. (1998). Plants used in Guatemala for the treatment of protozoal infections. I. Screening of activity to bacteria, fungi and American trypanosomes of 13 native plants. J. Ethnopharmacol., 62(3), 195-202.
  14. Sawant, R., & Godghate, A. (2013). Preliminary phytochemical analysis of leaves of Tridax procumbens Linn. International Journal of Science, Environment and Technology, 2(3), 388-394.
  15. Kumar, L., Prasad, A., Iyer, S., & Vaidya, S. (2012). Pharmacognostical, phytochemical and pharmacological review on Tridax procumbens. International Journal of Pharmaceutical & Biological Archives, 3(4), 747-751.
  16. Ikewuchi, J. C. (2012). Alteration of Plasma Biochemical, Haematological and Ocular Oxidative Indices of Alloxan Induced Diabetic Rats by Aqueous Extract of Tridax procumbens Linn (Asteraceae). EXCLI Journal, 11, 291-308.
  17. Policegoudra, R. S., Chattopadhyay, P., Aradhya, S. M., Shivaswamy, R., Sing, L., & Veer, V. (2014). Inhibitory effect of Tridax procumbens against human skin pathogens. Journal of Herbal Medicine, 4(2), 83-88.
  18. Jindal, A., & Kumar, P. (2012). Antimicrobial activity of alkaloids of Tridax procumbens L. against human pathogens. International Journal of Pharmaceutical Sciences and Research, 3(9), 3481-3485.
  19. Saxena, M., Mir, A. H., Sharma, M., Malla, M. Y., Qureshe, S., Mir, M. I., & Chaturvedy, Y. (2013). Phytochemical screening and in-vitro antioxidant activity isolated bioactive compounds from Tridax procumbens Linn. Pak J. Biol. Sci., 16(24), 1971-1977.
  20. Tiwari, U., Rastogi, B., Singh, P., Saraf, K., & Vyas, S. (2004). Immunomodulatory effects of aqueous extract of Tridax procumbens in experimental animals. Journal, 92(1), 113-119.
  21. Saxena, M., Mir, A. H., Sharma, M., Malla, M. Y., Qureshe, S., Mir, M. I., & Chaturvedy, Y. (2013). Phytochemical screening and in-vitro antioxidant activity isolated bioactive compounds from Tridax procumbens Linn. Pak J. Biol. Sci., 16(24), 1971-1977.
  22. Kethamakka, S. R. P., & Deogade, M. S. (2014). Javanti veda (Tridax procumbens) unnoticed medicinal plant by Ayurveda. Journal of Indian System of Medicine, 2(1), 6-20.
  23. Saxena, V., & Albert, S. (2005). ?-Sitosterol-3-O?-D-xylopyranoside from the flowers of Tridax procumbens Linn. Journal of Chemical Sciences, 117(3), 263-266
  24. Jhariya, S., Rai, G., Yadav, A. K., Jain, A. P., & Lodhi, S. (2015). Protective effects of Tridax procumbens Linn. Leaves on experimentally induced gastric ulcers in rats. Journal of Herbs, Spices & Medicinal Plants, 21(3).
  25. Manjamalai, A., Kumar, M. M., & Grace, V. M. B. (2012a). Essential Oil of Tridax procumbens L induces apoptosis and suppressed angiogenesis and lung metastasis of the B16F10 cell line in C57BL/6 mice. Asian Pacific J Cancer Prev., 13(11), 5887-5895.
  26. Kamble, S. I., & Dahake, P. R. (2015). Preliminary phytochemical investigation and study on antimicrobial activity of Tridax Procumbens Linn. International Refereed Multidisciplinary Journal of Contemporary Research, 2(3), 388-394.
  27. A. Jayashree, M. Sivaprakasam, “Studies on the antibacterial activity of the extracts from Tridax procumbens L and Ixora coccinea L”, Biomedicine,Vol. 28, Issue. 3, pp. 190-94, 2008.
  28. G. Babu, Sanjeeva, K. L. Bairy, “Effect of Tridaxprocumbens on burn wound healing”, Indian Drugs, Vol. 40, Issue. 8, pp. 488-91, 2003.
  29. P.V.Diwan, L.D.Tilloo, D.Kulkarni,“Influence of Tridax procumbens on wound healing”, Indian J. Med Res, Vol. 75, pp. 450-54, 1982.
  30. Gaikwadi, Vadlamudi, V.P. Waghmaee, S.P. Maral, V.J. Ranteke, V.D. Dhok, “Phytochemical analysis of aqueous extract of few medicinal plants”, Journal of Ethnopharmacology, Vol. 2, pp. 91-92, 2003.
  31. S. Mundada, R. Shivhare, “Pharmacology of Tridax procumbens”, International Journal of Green Pharmacy, Vol. 5, pp. 91-94, 2008.
  32. A. Jain and A. Jain, “Tridax procumbens(L): A weed with Immense Medicinal Importance: A Review”, International Journal of Pharma and BioSciences, Vol. 3, Issue. 1, pp. 544-52, 2012.
  33. S.L. Udupa, A.L. Udupa, DR. Kulkarni, “India Plantamedica”, Indian Journal of Pharmaceutical Sciences, Vol. 57, pp. 325-27,1991.
  34. B. Sailaja, K. Bharathi, K.V.S.R.G. Prasad, “Protective effect of Tridax procumbens L. on Calcium Oxalate Urolithiasis and oxidative stress”, An International Journal of Advances in Pharmaceutical Sciences, Vol. 2, pp. 9-14, 2011.
  35. https://images.app.goo.gl/KEeHHha7vEiSDzY3
  36. A. Taddei, A.J. Rosas-Romero, “Bioactivity studies of extracts from Tridax procumbens”, Phytomedicine,Vol. 7, Issue. 3, pp. 235-38, 2000.
  37. R. Chandar; A.K. Khanna, R. Kanwal, A.K. Rastogi, “Antioxidant and lipid lowering activities of Indian Black Tea”, Ind. J. Clinical Biochem., Vol. 20, Issue. 1, pp. 153-59, 2005.
  38. R.B. Mahato, R.P. Chaudhary,“Ethnomedicinal study and antibacterial activities of selected plants of Palpa district”, Nepal. Scientific World,Vol. 3, Issue. 3, pp. 26-31, 2005.
  39. C. Pai, U. Kulkarni, M. Borde, S. Murali, P. Mrudula , Y. Deshmukh, “Antibacterial Activity of Trida xprocumbens with Special Reference to Nosocomial Pathogens”, British Journal of Pharmaceutical Research, Vol. 1, Issue. 4, pp. 164-73, 2011.
  40. R. Nia, D.H. Paper, E.E. Essien, O.H. Oladimeji, K.C. Iyadi and G. Franz,“Investigation into in-vitro radical scavaging and in-vivo antiinflammatory potential of Tridax procumbens”, Nigerian journal of physiological science,Vol. 18, Issue. 1, pp. 39-43, 2003.
  41. R. S. Bhat, J. Shankrappa, H. G. Shivakumar, “Formulation and evaluation of polyherbal wound treatments”, Asian Journal of Pharmaceutical Sciences, Vol. 2, Issue. 1, pp. 11-17, 2007.
  42. D. A. Bhagwat, S. G. Killedar, R. S. Adnaik. Antidiabetic activity of leaf extract of Tridax procumbens. Intnl. J. Green Pharma, 2008, 2, 126- 128 .
  43. R.B.Mahato and R.P.Chaudhary.Ethomedicinal study and antibacterial of selected plants of Palpa district ,Nepal Scientific World ,2005,3(3),26-31.
  44. M.K. Oladunmoye. Immunomodulatory effects of ethanolic extract of Tridax procumbens on swiss Albino rats orogastrically dosed with pseudomonas aeruginosa (NCIB 950). International journal of tropical medicine, 2006, 1 (4), 152-155.
  45. U. Tiwari , B. Rastogi, P. Singh, D. K. Saraf and S. P. Vyas. Immunomodulatory effects of aqueous extract of Tridax procumbens in experimental animals. Journal of Ethnopharmacology, 2004, 92, 113–119.
  46. R Vilwanathan., K. S. Shivashangari and T. Devak. Hepatoprotective activity of Tridax procumbens against dgalactosamine/lipopolysaccharide-induced hepatitis in rats.Journal of Ethnopharamacology,2005,101,55-60.
  47. Vishnu priya P, Radhika K, Siva kumar R, Sri Ramchandra M, Prameela Devi Yand A.Srinivas Rao; An International Journal of Advances In Pharmaceutical Sciences,Vol. 2 (1) January -February 2011;26-30.
  48. V.Bharathi, Dr.Kalavathi, A.Shanmuga priya, S.Jannathul Firdous; anti-obesity effect of tridax procumbens in atherogenic diet-induced obese ratsIJPT, March-2011, Vol. 3, Issue No.1: 1565-1569.
  49. Gupta S, Yadava JNS and Tondon JS (1993). Antisecretory (anti-diarrheal) activity of Indian medicinal plants against E. coli enterotoxin- induced secretion in rabbit and guinea pig ileal loop models. International J. of Pharmacology, 31(3): 198-204.
  50. Rajkumar S and Jebanesan A (2007). Repellent activity of selected plant essential oils against the malarial fever mosquito Anopheles stephensi Trop. Biomed., 24(2): 71-5
  51. https://images.app.goo.gl/SoYtUf8B5sDpQf2Z9

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Rutuja G. Jogdande
Corresponding author

Department of Pharmaceutical Chemistry  Ashokrao Mane Institute of Pharmacy, Ambap-416112, India

Photo
Priya R. Kamble
Co-author

Department of Pharmaceutical Chemistry  Ashokrao Mane Institute of Pharmacy, Ambap-416112, India

Photo
Ashwini Chougule
Co-author

Department of Pharmaceutical Chemistry  Ashokrao Mane Institute of Pharmacy, Ambap-416112, India

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Jaya Kamble
Co-author

Department of Pharmaceutical Chemistry  Ashokrao Mane Institute of Pharmacy, Ambap-416112, India

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Nilesh Chougule
Co-author

Department of Pharmaceutical Chemistry  Ashokrao Mane Institute of Pharmacy, Ambap-416112, India

Rutuja Jogdande, Priya Kamble, Ashwini Chougule, Jaya Kamble, Nilesh Chougule, Pharmacological Activity Of Tridax Procumbens, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 1, 601-611. https://doi.org/10.5281/zenodo.10563529

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