View Article

Abstract

Transverse myelitis is defined by inflammation in the spinal cord and has clinical symptoms in the form of neurological dysfunction in autonomic, sensory, and motor pathways, as a result of the channel passing the rostral border of inflammation. Acute Transverse myelitis may be a rare syndrome. A 16-year male patient was admitted with the main complaint that his hand grip had deteriorated over the previous two days, a challenge while mixing meals. On Examination the patient and his vitals were found to be stable but strength of distal part of upper limbs was 1/5 and lower limbs was 5/5. MRI cervical spine with a screening of the whole spine was found to be long segment fusiform thickening of the cervical cord extending from C3 to the superior endplate of D1. He was treated with methyl prednisolone 1gm, IV and other symptomatic and supportive treatment and 80% improvement in the hand grip was noticed.

Keywords

Transverse myelitis, Immunosuppressant, plasmapharesis, plantar reflexes

Reference

  1. Lim PAC. Transverse myelitis. Essentials of Physical Medicine and Rehabilitation. 2020; 952–9. doi:10.1016/b978-0-323-54947-9.00162-0
  2. Pandit L. Transverse myelitis spectrum disorders. Neurology India. 2009; 57 (2):126. doi:10.4103/0028-3886.51278
  3. Jie Chan SS, Kaliya-Perumal A-K, Yeo QY, Y.L. Oh J. Transverse myelitis masquerading as cauda equina syndrome, stroke and cervical myelopathy. BioMedicine. 2020; 10(1). doi:10.37796/2211-8039.1005
  4. Christopher G. Simone, Prabhu D. Emmady, Transverse Myelitis. Statpearl. 2022
  5. Goh C, Desmond PM, Phal PM. MRI in transverse myelitis. Journal of Magnetic Resonance Imaging 2014; 40 (6). doi: 10.1002/jmri.24563
  6. Awad A, Stuve O. Idiopathic transverse myelitis and neuromyelitis optica: Clinical Profiles,Pathophysiology and therapeutic choices. Current Neuropharmacology. 2011; 9(3):417–28. doi:10.2174/157015911796557948
  7. Weinshenker BG, O’Brien PC, Petterson TM. A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. 1999; 46:878–886. doi:10.1212/WNL.0b013e31823dc535.

Photo
Vankodoth sireesha
Corresponding author

assistant professor, CMR College of pharmacy, medchal

Photo
Tadikonda Rama Rao
Co-author

3.Professor, Principal, CMR College of Pharmacy, Hyderabad. Telangana

Photo
Y. Pravarsha
Co-author

Pharm D intern, CMR College of Pharmacy, Hyderabad, Telangana

Photo
Sumaya Sumaya
Co-author

intern, department of pharmD, CMR College of Pharmacy, Hyderabad, Telangana

Photo
Kompalli Varun
Co-author

intern, department of pharmD, CMR College of Pharmacy, Hyderabad, Telangana

Vankodoth Sireesha, Y. Pravarsha, Sumaya Sumaya, Kompally Varun, Rama Rao Tadikonda, Transverse Myelitis: A Rare Case Report, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 385-388. https://doi.org/10.5281/zenodo.10389739

More related articles
Formulation And In vitro Evaluation Of Bilayer Tab...
Mayur Aware, Sheetal Gondkar, Rishikesh Bachhav, ...
Artificial Intelligence in Computer- Aided Drug Design: A Comprehensive Review ...
Sakshi Bhope , Riddhi Shirbhate , Shruti Shende, Sapna Patel , Kamlesh Wadher, ...
The Science and Tradition of Calendula: A Review of Phytochemistry and Ethnophar...
Lalit Ambhore, Kaveri Bharat Jagtap , Leena Umesh Parkhi , Mahendra Siddheshwar Shendkar, Lahoo Balu...
Exosomes And Extracellular Vesicles as Emerging Drug Delivery Platforms...
Dr. Manisha S. Nangude, T. A. Dalvi, G. M. Choudhary, A. S. Desai, R. D. Damse, G. N. Dhere, G. S. M...
Related Articles
An Elaborative Review On Medicinal Values Of Aegle Marmelos (BAEL)...
Chitra janardan chavan , Chaitrali G.Markad , Deepti R.Indalkar , Kishor V. Otari, Trushali A. Mand...
Comprehensive Review on Semen Production, Premature Ejaculation, Contributing Fa...
Mohd Vaseem, Abdulla Ansari, Md Furquan Khan, Nayeem Ahmad, Mohd Saidurrehman, Syed Shariq, Mohd Abi...
Niosomes A Novel Drug Delivery System...
Poornima Kala, Vikas Dhawan, ...
In-Silico Evaluation of Flavone Derivatives for Cardioprotective Effects: A Comp...
Sneha Nandeshwar , Sapan Shah, Rida Saiyad, Nikita Gaikwad , Pooja Wankhade, ...