View Article

Abstract

Transverse myelitis is defined by inflammation in the spinal cord and has clinical symptoms in the form of neurological dysfunction in autonomic, sensory, and motor pathways, as a result of the channel passing the rostral border of inflammation. Acute Transverse myelitis may be a rare syndrome. A 16-year male patient was admitted with the main complaint that his hand grip had deteriorated over the previous two days, a challenge while mixing meals. On Examination the patient and his vitals were found to be stable but strength of distal part of upper limbs was 1/5 and lower limbs was 5/5. MRI cervical spine with a screening of the whole spine was found to be long segment fusiform thickening of the cervical cord extending from C3 to the superior endplate of D1. He was treated with methyl prednisolone 1gm, IV and other symptomatic and supportive treatment and 80% improvement in the hand grip was noticed.

Keywords

Transverse myelitis, Immunosuppressant, plasmapharesis, plantar reflexes

Reference

  1. Lim PAC. Transverse myelitis. Essentials of Physical Medicine and Rehabilitation. 2020; 952–9. doi:10.1016/b978-0-323-54947-9.00162-0
  2. Pandit L. Transverse myelitis spectrum disorders. Neurology India. 2009; 57 (2):126. doi:10.4103/0028-3886.51278
  3. Jie Chan SS, Kaliya-Perumal A-K, Yeo QY, Y.L. Oh J. Transverse myelitis masquerading as cauda equina syndrome, stroke and cervical myelopathy. BioMedicine. 2020; 10(1). doi:10.37796/2211-8039.1005
  4. Christopher G. Simone, Prabhu D. Emmady, Transverse Myelitis. Statpearl. 2022
  5. Goh C, Desmond PM, Phal PM. MRI in transverse myelitis. Journal of Magnetic Resonance Imaging 2014; 40 (6). doi: 10.1002/jmri.24563
  6. Awad A, Stuve O. Idiopathic transverse myelitis and neuromyelitis optica: Clinical Profiles,Pathophysiology and therapeutic choices. Current Neuropharmacology. 2011; 9(3):417–28. doi:10.2174/157015911796557948
  7. Weinshenker BG, O’Brien PC, Petterson TM. A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. 1999; 46:878–886. doi:10.1212/WNL.0b013e31823dc535.

Photo
Vankodoth sireesha
Corresponding author

assistant professor, CMR College of pharmacy, medchal

Photo
Tadikonda Rama Rao
Co-author

3.Professor, Principal, CMR College of Pharmacy, Hyderabad. Telangana

Photo
Y. Pravarsha
Co-author

Pharm D intern, CMR College of Pharmacy, Hyderabad, Telangana

Photo
Sumaya Sumaya
Co-author

intern, department of pharmD, CMR College of Pharmacy, Hyderabad, Telangana

Photo
Kompalli Varun
Co-author

intern, department of pharmD, CMR College of Pharmacy, Hyderabad, Telangana

Vankodoth Sireesha, Y. Pravarsha, Sumaya Sumaya, Kompally Varun, Rama Rao Tadikonda, Transverse Myelitis: A Rare Case Report, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 385-388. https://doi.org/10.5281/zenodo.10389739

More related articles
Development and Assessment of Herbal Formulation f...
Kirtana Gajul, Vrunal More, Vaibhav Gaikwad, Ahemad Noormahamad ...
A Review: Microencapsulation...
Tejas Zond, Appasaheb Kuhile , Dikshita Valvi , Sapna Raut, ...
Undergraduate Students’ Industrial Work Experience in Pharmacy Education: A Re...
Nnenna Ajagu, Nnadi Ifesoluchi Favou, Adaora Agatha Ugwu, Kalu Beatrice Arunsi, Maureen Aneto, ...
Rise In Heart Attack Cases Post Covid-19 Vaccination in India: A Review Article ...
Dr. Rahim Jamadar, Dr. Kalpana Jadhav, Dr. Milind Godbole, Dr. Abhijeet Mane-Patil, ...
An Updated Review on Shankhpushpi as Herbal Medicine (Convolvulus Pluricaulis)...
Akshay Shyamsundar, Mamta Surve, Sakshi Kharate, Dr. Swati Deshmukh, ...
Related Articles
Antifungals: From Pharmacokinetics to Clinical Practice...
Shruti Kamble , Supriya Mhamane, Dr. R. R. Bendgude, ...
Formulation, Optimization and Evaluation of In-situ Gelling Liquid Oral Formulat...
Sagar Ravasaheb Pagade , Pranjal Chougule, Nilesh Chougule, ...
Aquasomes: A Novel Carrier for Drug Delivery ...
Akash Ingale, Rushikesh Lohar , Manoj Bachche, Omkar Shelake , Dr. Nilesh Chougule, Dr. Parag Patil...
Formulation of Different Dosage Forms of Insulin ...
Shaikh Shirin Fatema Maulana, Waghmare Vyanktesh , Wangawar Pallavi , Shinde Devanand , Suryawanshi ...
Development and Assessment of Herbal Formulation for Kidney Stone...
Kirtana Gajul, Vrunal More, Vaibhav Gaikwad, Ahemad Noormahamad Nadaf, Shailaja Devsani, ...
More related articles
Development and Assessment of Herbal Formulation for Kidney Stone...
Kirtana Gajul, Vrunal More, Vaibhav Gaikwad, Ahemad Noormahamad Nadaf, Shailaja Devsani, ...
A Review: Microencapsulation...
Tejas Zond, Appasaheb Kuhile , Dikshita Valvi , Sapna Raut, ...
Development and Assessment of Herbal Formulation for Kidney Stone...
Kirtana Gajul, Vrunal More, Vaibhav Gaikwad, Ahemad Noormahamad Nadaf, Shailaja Devsani, ...
A Review: Microencapsulation...
Tejas Zond, Appasaheb Kuhile , Dikshita Valvi , Sapna Raut, ...