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Abstract

The present research work is based on the formulation of herbal granules by incorporating the aqueous extract of onion peels, garlic peels, potato peels, and chilli pedicles. The aqueous extract of the plant was extracted and then subjected to phytochemical tests, fluorescence tests, antioxidant activity, and anticancer activity. Then it was formulated into granules and evaluated for various parameters like angle of repose, bulk density, and tapped density. The preliminary chemical studies showed that the extract contains flavonoids, alkaloids, glycosides, carbohydrates, vitamins, and tannins. The formulated granules exhibited good flow properties, which showed good angle of repose, bulk density, and tapped density. The antioxidant and anticancer activity showed the herbal granules to be more potent. An herbal granule was prepared, as this particular formulation can be used for plant growth hormone. The IC50 value of aqueous extract shows 166.486 ?g/ml for antioxidant activity (shown in Table no 3.) and IC50 value of Standard Ascorbic acid shows 23.7148 ?g/ml antioxidant activity. (Shown in Table no. 3). The LC50 value of aqueous extract shows 212.97 ?g/ml for anticancer activity (shown in Table no.4) & The LC50 value of standard extract shows 0.00 ?g/ml for anticancer activity. (Shown in Table no.4).

Keywords

Antioxidant, Anticancer, brine shrimp, Soxhlet apparatus, LC50 Value, IC50 Value

Reference

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Sushant Mane
Corresponding author

Sahyadri College of Pharmacy Methwade, Sangola-413307.

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Sangram Falake
Co-author

Sahyadri College of Pharmacy Methwade, Sangola-413307.

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Somnath Mali
Co-author

Sahyadri College of Pharmacy Methwade, Sangola-413307.

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Dr. Ashpak Tamboli
Co-author

Sahyadri College of Pharmacy Methwade, Sangola-413307.

Sushant Mane*, Sangram Falake, Somnath Mali, Dr. Ashpak Tamboli, To Study Antioxidant & Anticancer activity of aqueous extract of Onion peels, Potato peels, Garlic peels and Chilli pedicle, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 7, 155-161. https://doi.org/10.5281/zenodo.8113840

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