View Article

  • Bilayer Floating Tablet : A Novel Floating Tablet
  • 1Department of Pharmaceutics, R. G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213
    2Department of Pharmacology, R. G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213

Abstract

Out of various drug delivery system the novel drug delivery system is overcomes and then physiological problems of gastric retention by decreasing fluctuations in blood drug concentration level with consequent reduction in the undesirable toxicity and poor efficiency. Approaches have their been introduced to prolong gastric residence time such as the floating system, modified shape, swelling index, expanding system and high density system. Two layer floating drug delivery system is combined principle of bilayer tablet as well as floating mechanism. Bilayer floating tablet is new in the era for the successful development of the controlled release formulation along with the different features to provide a way of successful drug delivery system. The purpose of this paper is to the following Review of the principle of floating drug delivery system, current technology used in the development of same as well as summarizes in the applications, advantages and disadvantages, characterization, evaluation methods and future potential for the bilayer floating tablets.

Keywords

Bilayer(Two layer) Floating Drug Delivery Systems, Controlled Release, Gastro retentive Dosage Forms, Immediate Release Layer, Hydro dynamical balanced systems

Reference

  1. Parmjit Kaur, Sonia Dhiman, Sandeep Arora Floating Bilayer Tablet Technology: A Review ,International Journal of Pharmaceutical Sciences Review and Research., 2013; 19(1): 112-122. 
  2. Priyamvada Barthwal, G Ganarajan and Preeti Kothiyal, Bilayer: A Review International Journal Of Pharmaceuticle And Chemicle Science, 2013; 2(4): 1788-1797. 
  3. Rohit D. Jondhale, Pallavi S. Gadhave, Ashish A. Mahajan, Mohini S. Bodhane Floating Drug Delivery System: A Review, World Journal Of Pharmacy And Pharmaceuticle Science, 4(10): 562-575. 
  4. Sarvesh D Parsekar, Shruti Prabhu, Amitha Shetty, Mohd Azharuddin and AR. Shabaraya, A Brief Review on Floating Bilayer Tablet as a Convenient Gastroretentive Drug Delivery System International Journal Of Pharmaceuticle And Chemicle Sciences, 2014; 3(2): 420-430. 
  5. Neha Narangi,An Updated Review On: Floating Drug Delivery System (FDDS),International Journal Of applied Pharmaceutics, 2011; (3)1: 1-7. 
  6. Sachin S. Kale, Viraj S. Saste, Prajkta L. Ughade, Dheeraj T. Baviskar Review Article Bilayer tablet 2011; 9(1): 25-29. 
  7. Abhishek Chandel, Kapil Chauhan, Bharat Parashar, Hitesh Kumar, Sonia Arora, “Floating Drug Delivery Systems:A Better Approach” International Current Pharmaceutical Journal., 2012; 1(5): 110-118. www.wjpps.com Vol 5, Issue 02, 2016. 1423 Pethkar et al. 
  8. Roy Chowdhury Santanu,Verma Pooja, Floating Drug Delivery Syste- A New Era In Novel Drug Delivery System. IJPRBS, 2012; 1: 91-107. 
  9. Neha Narang, An Updated Review On: Floating Drug Delivery System, IJAP, 2011; 3(1). 
  10. Amit Kumar Nayak , Ruma Maji, Biswarup Das, Gastroretentive Drug Delivery Systems: A Review, Asian Journal Of Pharmaceutical And Clinical Research, January-March 2010; 3(1). 
  11. Shaha SH, Patel JK, Pundarikakshudu K And Patel NV: An Overview Of Gastroretentive Floating Drug Delivery System Asian Journal Of Pharmaceutical Sciences., 2009; 4(1): 65-80.
  12. Bhise SD And NH Aloorkar: Formulation And In Vitro Evaluation Of Floating Capsules Of Theophylline. Indian J Pharm Scien., 2008; 70(2): 88-93. 1
  13. Arunachalam A, Karthikeyan M, Konam Kishore, Prasad H Pottabathula, Sethuraman S And Ashutosh Kumar S:Floating Drug Delivery Systems: A Review.Int. J. Res. Pharm. Sci., 2011; 2(1): 76-83. 
  14. Kulkarni A and Bhatia M. Developments And Evaluation Of Bilayer Floating Tablets Of Atenolo And Lovastatin For Biphasic Release Profile, Iranian Journal of Pharmacy and Research. 2009; 8(1): 15 -25. 
  15. Shaikh TK, Gadhave MV and Jadhav SL. Different Techniques In Bilayer Tablets A Review., International Journal of Universal Pharmacy And Life Sciences. 2012; 1(1) :1-8. 
  16. Subrahmanyam CVS And Setty JT:Laboratory Manual Of Physical Pharmaceutics, Jain MK For Vallabh Prakashan IJPR., 2010. 
  17. Lachman L, Liberman HA and Joshep KL. The Theory And Practice of Industrial Pharmacy, Varghese House Bombay 3rd edition, 430 – 431. 
  18. Pooja M., kamal S., Navneet S., Surender V, Sanju N., Vinay V.,An Overview on recent advancements and development in gastroretentive buoyant drug delivery system Der pharmacia sinica 2011; (1)2: 161-169.

Photo
Mayur Aware
Corresponding author

Department of Pharmaceutics, R. G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213

Photo
Sheetal Gondkar
Co-author

Department of Pharmaceutics, R. G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213

Photo
Rishikesh Bachhav
Co-author

Department of Pharmacology, R. G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213

Mayur aware, Sheetal gondkar, Rishikesh bachhav, Bilayer Floating Tablet : A Novel Floating Tablet, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 2, 86-93. https://doi.org/10.5281/zenodo.5895074

More related articles
Lifestyle Intervention: The Quintessential tool to...
J.C Balachandar, Sanjeev Kumar Yadav, Amit Kumar Agrawal, S. Irsh...
Quality By Design: A Concise Review In Pharmaceuti...
Netra Machhindra Adhav , Dr.Rishikesh.S. Bachhav, Shubhangi Vishw...
Unraveling The Neurobiological Mechanisms And Ther...
Arnab Roy, Prof. (Dr) K. Rajeswar Dutt, Maheswar Prasad Deep, Abr...
Clinical Data Management: A Comprehensive Overview Of Methods And Workflow In Cl...
Akash Bhagwan Aher, Atharv Chagan Gadhe, Prashant Vilas Bhakare, Prof.Shweta Kahar, Prof.Kranti Pakh...
Formulation and Evaluation of Herbal Shampoo ...
Sanket Ashokrao Hood , Ganesh Tulshidas Harkal, Aman Girish Ghivdhonde, Nilesh Gajanan Lokhande, Har...
Niosomes Used In Treatment Of Cancer: A Review...
Sudarshan Kale, Shraddha vaishnav , Vinit khairnar , chaitali markand , ...
Related Articles
Transferosomes, Revolutionizing NSAIDS Delivery For Improved Therapeutic Efficac...
Anjitha M, K. Selvaraju, N. L. Gowrishankar, Athulya Prasad, Arun Giri Raj. V, Shabna. S, ...
Sublingual Dosage Form...
Namrata S. Revar, Samruddhi B. Sawant, Sanjeevani D. Rupwate, ...
Lifestyle Intervention: The Quintessential tool to prevent and reverse Type 2 Di...
J.C Balachandar, Sanjeev Kumar Yadav, Amit Kumar Agrawal, S. Irshad Ahamed, A. Ayeshamariam, M. Jaya...
More related articles
Lifestyle Intervention: The Quintessential tool to prevent and reverse Type 2 Di...
J.C Balachandar, Sanjeev Kumar Yadav, Amit Kumar Agrawal, S. Irshad Ahamed, A. Ayeshamariam, M. Jaya...
Quality By Design: A Concise Review In Pharmaceutical Sciences...
Netra Machhindra Adhav , Dr.Rishikesh.S. Bachhav, Shubhangi Vishwanath Bhalerao , ...
Unraveling The Neurobiological Mechanisms And Therapeutic Challenges In Anxiety ...
Arnab Roy, Prof. (Dr) K. Rajeswar Dutt, Maheswar Prasad Deep, Abrarul Haque, Archana Rani, Nahida Kh...
Lifestyle Intervention: The Quintessential tool to prevent and reverse Type 2 Di...
J.C Balachandar, Sanjeev Kumar Yadav, Amit Kumar Agrawal, S. Irshad Ahamed, A. Ayeshamariam, M. Jaya...
Quality By Design: A Concise Review In Pharmaceutical Sciences...
Netra Machhindra Adhav , Dr.Rishikesh.S. Bachhav, Shubhangi Vishwanath Bhalerao , ...
Unraveling The Neurobiological Mechanisms And Therapeutic Challenges In Anxiety ...
Arnab Roy, Prof. (Dr) K. Rajeswar Dutt, Maheswar Prasad Deep, Abrarul Haque, Archana Rani, Nahida Kh...