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Abstract

A Dry Powder Inhaler (DPI) is a device that inhales dry powdered medicine into the lungs. DPIs are frequently used to treat respiratory conditions like COPD, bronchitis, and asthma. In recent years, interest in DPI as an effective and ecologically friendly method of medication delivery to the lung has increased. Only an effective metering mechanism, a well-chosen device, and an appropriate powder composition will allow a dry powder inhaler to achieve these objectives. The three primary categories are nebulizer, pMDI, and DPI. DPIs, which provide medicine to the lungs in the form of a dry powder, are an alternative to pMDI. To ensure that the patient receives the same dosage each time at a varied airflow rate, API particles must be present in the size range of 1 to 10 m. Four different formulation procedures, including carrier-free, drug carrier, drug additive, and drug carrier additive, are used to create DPI. 'Twin Stage Impingner' completes the lung deposition research. The inward breath device, which is primarily divided based on measurements into single-unit and multi-dosage stores, is essential for achieving appropriate delivery of breathed in medication to the lung.

Keywords

Pulmonary route, Dry powder inhaler, Carrier particle, Inhalation Device

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Trupti Bhalekar
Corresponding author

Department of Quality Assurance, PRES College of Pharmacy (Women’s), Chincholi, Nashik-422102

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Kalpana Sable
Co-author

Department of Quality Assurance, PRES College of Pharmacy (Women’s), Chincholi, Nashik-422102

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Jaya Mehetre
Co-author

Department of Quality Assurance, PRES College of Pharmacy (Women’s), Chincholi, Nashik-422102

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Kiran Dhamak
Co-author

Department of Quality Assurance, PRES College of Pharmacy (Women’s), Chincholi, Nashik-422102

Trupti Bhalekar*, Kalpana Sable, Jaya Mehetre, Kiran Dhamak, Dry Powder Inhalers: A Critical Evaluation Of Their Effectiveness And Accessibility, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 7, 288-301. https://doi.org/10.5281/zenodo.8173889

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