Department of Pharmaceutical Quality Assurance, Dr. Ithape Institute Of Pharmacy, Sangamner, Tal- Sangamner, Dist- Ahmednagar 422605, India
The specified paper presents a systematic review conduct on different methods for the analysis o the antihistamine drug. The focus of the article I to verify how the validation process of an analytical method I performed.Chlorpheniramine is approved by the U.S. Food and Drug administration is safe and effective when used to antihistamine and allergies. It is a prescription medication ues to preventing the release of histamine by acts on the brain and relieves symptoms of allergies. To provide relief form allergies symptoms such as sneezing,running nose, watery eyes, itching, swelling, and congestion or stiffness. Most recent analytical methods such as various spectroscopic methods ( simultaneous estimation, Q absorption ratio) and chromatoghraphic methods (RP-HPLC, HPTLC, LC) are included in review. In different articles, the study is conducted on various analytical parameters such as mobile phase, the ratio of mobile phase, stationary phase, flow rate, wavelength ect. The observation are made based on Retention time, Area of peak, peak height, therotical plates, AUC, ect. From the data found in the literature, a comparison is made between different methods and observation having different base properties.
Sonali U. Navale, Chetana A. Padekar, Sonali S. Ghuge, Monali S. Ghuge, Gayatri S. Gaikwad, Comprehensive Review On Analytical Methods For Determination Of Chlorpheniramine Maleate In Pharmaceutical Dosage Form And Bulk, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 2, 224-232. https://doi.org/10.5281/zenodo.10643052
10.5281/zenodo.10643052
