1,2,3,4Department of Pharmaceutics, Sarada Vilas College of Pharmacy, Mysuru, Karnataka, India
5Department of Pharmacognosy, Sarada Vilas College of Pharmacy, Mysuru, Karnataka, India
Oral disintegrating films (ODF) hold great promise for novel and inventive drug delivery methods. Because it is flexible and comfortable to use, mouth dissolving film is the most advanced oral solid dosage form available. Mouth dissolving films are oral solid dosage forms that, when placed in the mouth without water or chewing, dissolve and disintegrate within a minute. With this dosage form, the drug can avoid the first pass metabolism, potentially increasing its bioavailability. Mouth dissolving films have the ability to reduce dosage, improve the onset of action, and get rid of choking anxiety. Plasticized hydrocolloids and taste-masking agents for APIs are laminated using solvent casting and semisolid casting techniques in the formulation of mouth-dispersing films, yielding both functional and visual characteristics. The most widely used technique is solvent casting because of its superior physical properties, finely glossy films produced, and excellent thickness uniformity. Mouth dissolving films are evaluated according to several parameters, such as thickness and physical attributes like disintegration and dissolution time. An overview of formulation methods, packaging, evaluation standards, and some commercially available mouth dissolving film products are given in this review.
Nagendra R. , Sheetal P. , Nanditha V. V. , Venkatesh K. , Hanumanthachar Joshi, Oral Disintegrating Film: A Review, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 2, 206-216. https://doi.org/10.5281/zenodo.10640441
10.5281/zenodo.10640441
