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Abstract

Banana flower (Musa spp.) is an underexploited agricultural by-product that possesses considerable nutritional and therapeutic value. It is a rich source of dietary fiber, bioactive constituents, and essential minerals, particularly iron. Recent research has emphasized its potential application in functional foods as well as nutraceutical formulations. This review highlights the nutritional profile, bioactive components, iron content, and the role of banana flower in developing iron-enriched nutraceutical granules. Furthermore, it discusses various processing methods, formulation approaches, and evaluation criteria to support its utilization as a value-added health product.

Keywords

Banana flower (Musa paradisiaca), Iron-rich nutraceutical, Wet granulation technique, Dietary fiber and bioactive compounds, Iron deficiency anemia

Introduction

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Iron deficiency anemia remains one of the most common nutritional disorders globally, with a higher prevalence in developing nations such as India. The adverse effects and limitations associated with synthetic iron supplements have led to increasing interest in natural, cost-effective, and plant-derived alternatives. In this regard, banana flower, which is generally discarded as a waste product during banana cultivation, has gained attention as a promising nutraceutical source due to its rich nutritional and phytochemical composition.

Various studies, including those conducted by Bhaskar et al. (2012) and Mohapatra et al. (2010), have demonstrated the significant nutritional and functional properties of banana flower. It is abundant in dietary fiber, phenolic compounds, and essential minerals such as iron, making it a suitable candidate for incorporation into functional food products. Recent investigations further validate its potential in the development of value-added formulations.

The formulation of nutraceutical granules using banana flower provides an efficient means of nutrient delivery, enhances stability, and improves ease of consumption. Therefore, its utilization not only offers health benefits—especially in combating iron deficiency—but also contributes to economic value by transforming agricultural waste into a functional product.

2.1 Nutritional Importance of Banana Flower

Banana flower (Musa spp.) is recognized as a highly nutritious plant component with significant potential in the preparation of functional foods and nutraceutical products. Scientific studies indicate that it contains a balanced composition of macronutrients, micronutrients, and bioactive compounds that contribute positively to human health.

One of the key nutritional features of banana flower is its high dietary fiber content. This fiber plays an important role in supporting digestive health, enhancing bowel regularity, and reducing the risk of chronic conditions such as cardiovascular diseases and diabetes. As reported by Bhaskar et al. (2012), the fiber content also contributes to antioxidant activity and aids in metabolic regulation.

In addition to fiber, banana flower contains moderate amounts of proteins and carbohydrates, making it a valuable supplementary ingredient in food formulations. It also provides essential vitamins such as vitamin C and vitamin E, both of which function as antioxidants. These vitamins help in protecting the body against oxidative stress and in strengthening the immune system.

Furthermore, banana flower is a good source of important minerals including iron, calcium, magnesium, and potassium. Its notable iron content makes it particularly beneficial for the prevention and management of iron deficiency anemia.

2.2 Nutritional Composition of Banana Flower (per 100 g edible portion)

 

Nutrient

Amount (Approx.)

Nutritional Significance

Energy

50–60 kcal

Provides low-calorie energy

Carbohydrates

9–12 g

Source of energy

Protein

1.5–2.0 g

Supports body growth and repair

Fat

0.5–1.0 g

Very low fat content

Dietary Fiber

5–6 g

Improves digestion, prevents constipation

Vitamin C

10–15 mg

Boosts immunity, antioxidant

Vitamin E

1–2 mg

Protects cells from oxidative damage

Calcium

40–60 mg

Supports bone health

Iron

2–4 mg

Helps prevent anemia

Magnesium

30–50 mg

Supports metabolic functions

Potassium

300–400 mg

Maintains heart and muscle function

Total Phenolic Content

50–100 mg GAE

Antioxidant activity

 

 

 

 

 

 

 

4. Products Developed from Banana Flower

Banana flower (Musa spp.) has attracted increasing attention in recent years owing to its rich nutritional profile and adaptability in the development of various food products. Several research studies have demonstrated its successful incorporation into a wide range of value-added and functional food formulations.

One of the most common processing approaches involves converting banana flower into powder form, which serves as a key ingredient in multiple nutraceutical and food applications. This powdered form is widely utilized in the formulation of nutraceutical granules, capsules, and dietary supplements, particularly for enhancing iron intake and improving overall nutritional status (Saifullah et al., 2020).

Apart from nutraceutical applications, banana flower powder has also been incorporated into bakery products such as biscuits, bread, and muffins. The inclusion of banana flower significantly improves the dietary fiber and mineral content of these products, thereby making them healthier alternatives to conventional bakery items (Singh et al., 2016).

Studies conducted by Sharmila et al. (2016) have further highlighted its potential in the preparation of functional beverages and plant extracts. Due to its antioxidant properties, banana flower contributes to additional health benefits when used in herbal drinks and health tonics.

In addition, banana flower has long been used in traditional culinary practices, particularly in Asian cuisines. It is commonly prepared as curries, pickles, and chutneys, which not only enhance dietary variety but also offer medicinal advantages.

Overall, banana flower can be effectively utilized to develop a variety of products, including:

  • Nutraceutical granules and powders
  • Bakery products (such as biscuits and bread)
  • Functional beverages

5. Standard Method Used (Wet Granulation Technique)

 

 

 

 

6. MATERIALS AND METHODS (Wet Granulation Method)

6.1 Materials

  • Banana flowers (Musa paradisiaca) were sourced from local agricultural fields.
  • The collected plant material was carefully washed with clean water to remove adhered impurities.
  • The outer layers (bracts) were discarded, and the inner edible portion was cut into smaller segments.
  • These pieces were dried in a hot air oven maintained at 40–45°C for 5–7 days to achieve complete dehydration.
  • The dried material was then reduced to a fine powder using suitable grinding equipment.
  • The prepared powder was stored in tightly sealed containers to prevent moisture absorption.

6.2 Chemicals and Excipients

  • A combination of ethanol and chloroform was used as the solvent system for extraction.
  • Corn starch was incorporated as a disintegrant to facilitate tablet breakdown.
  • Binding of granules was achieved using gum acacia or carboxymethyl cellulose (CMC).
  • Stearic acid was included to act as a lubricant during formulation.
  • Colloidal silicon dioxide was utilized to enhance powder flow as a glidant.
  • All substances used in the study were of analytical grade to maintain experimental accuracy.

6.3 Preparation of Banana Flower Extract

  • A measured quantity of 100 g of powdered banana flower was taken for extraction.
  • The extraction process was carried out using a Soxhlet apparatus with a solvent mixture of ethanol and chloroform in a 75:25 proportion.
  • The procedure was continued until no further extraction of constituents was observed.
  • The resulting extract was separated from solid residues by filtration using Whatman No. 1 filter paper.
  • The solvent was removed by evaporation at a controlled temperature of 50°C, yielding a concentrated crude extract.
  • The extract obtained was stored under refrigerated conditions at 4°C until further analysis.

6.4 Phytochemical Screening

  • The prepared extract underwent qualitative phytochemical evaluation.
  • Standard tests were performed to identify the presence of major bioactive compounds, including:
    • Alkaloids
    • Flavonoids
    • Tannins
    • Saponins
    • Terpenoids
    • Glycosides

7 .Evaluation Test of Banana Flower-Based Nutraceutical supplement granules

 

Table 7.1 Pre-Compression Parameters of Banana Flower Powder

 

Sr. No.

Parameter

Procedure (Standard Method)

Formula

Ideal Range / Significance

1

Bulk Density

Accurately weighed powder is poured into a measuring cylinder and initial volume is noted.

BD = W / V?

Indicates packing ability

2

Tapped Density

Cylinder is tapped until constant volume is achieved and final volume is recorded.

TD = W / Vt

Shows compressibility

3

Carr’s Index

Calculated using bulk and tapped density values to evaluate flow properties.

CI (%) = [(TD − BD) / TD] × 100

<15% = good flow

4

Hausner’s Ratio

Ratio of tapped density to bulk density is calculated.

HR = TD / BD

<1.25 = good flow

5

Angle of Repose

Powder is allowed to form a cone and angle is measured.

Tan θ = h / r

<30° = excellent flow

 

 

 

Table 7.2: Post-Granulation Evaluation of Nutraceutical Granules

 

Sr. No.

Parameter

Procedure (Standard Method)

Formula

Significance

1

Appearance

Granules are visually examined for color, shape, and uniformity.

Indicates quality

2

Particle Size

Granules are passed through standard sieves to determine size distribution.

Ensures uniformity

3

Moisture Content

Granules are dried and weight loss is calculated.

MC (%) = (W? − W?) / W? × 100

Affects stability

4

Iron Content

Sample is dissolved and analyzed using AAS/UV method.

Confirms nutrient level

5

In-vitro Release

Granules are tested in dissolution medium and samples are analyzed at intervals.

% Release = (Drug released / Total drug) × 100

Shows release rate

6

Flow Property

Flow behavior is observed practically or by flow rate methods.

Handling property

7

Solubility/Dispersibility

Granules are added to water and observed for dissolution behavior.

Nutrient availability

8

Stability Study

Granules are stored under different conditions and evaluated periodically.

Shelf-life

 

8. Iron Deficiency Condition in the Current Scenario

  • Iron deficiency remains one of the most prevalent nutritional disorders worldwide.
  • It is highly common among women, especially during pregnancy and menstruation, due to increased iron demands.
  • A rising trend of iron deficiency is observed among adolescents, mainly due to unhealthy and unbalanced eating habits.
  • Vegetarian diets often contain iron with lower bioavailability, which contributes to inadequate iron absorption.
  • High consumption of processed and junk foods, along with insufficient intake of green leafy vegetables, further worsens the condition.
  • Iron deficiency is a primary cause of anemia, leading to fatigue, weakness, and reduced physical performance.
  • It can weaken the immune system, increasing vulnerability to infections.
  • In students and young individuals, it may impair cognitive function, memory, and concentration.
  • Socioeconomic challenges and lack of nutritional awareness significantly affect proper dietary intake.
  • It continues to be a major public health concern in developing countries, including India.

9. Management of Iron Deficiency Using Banana Flower Nutraceutical Granules

  • Regular intake of nutraceutical granules prepared from banana flower may contribute to the improvement of iron levels in the body.
  • These granules are a natural source of iron, dietary fiber, and various bioactive constituents that aid in hemoglobin synthesis.
  • Their consumption helps in enhancing overall nutritional status and reducing symptoms such as fatigue and weakness.
  • They support digestive health, which in turn may promote better absorption of essential nutrients.
  • The formulation is considered suitable for adolescents, women, and individuals experiencing mild to moderate iron deficiency.
  • It can serve as a natural and safer alternative to conventional iron supplements, with a lower risk of adverse effects.

Recommended Dose

  • Adults: A daily intake of 5–10 g of granules, administered either once or in divided doses, is suggested.
  • Adolescents: A dosage of approximately 5 g per day is considered appropriate.
  • Mode of Administration: The granules may be consumed with water or milk, or can be incorporated into food preparations for ease of intake.
  • Duration of Use: The supplementation may be continued for a period of 4–8 weeks, or adjusted based on individual requirements.

 

10. RESULT AND DISCUSSION

 

Table: Preformulation (Pre-compression) Evaluation Results

Sr. No.

Parameter

Result (Observed)

Interpretation

1

Bulk Density

0.42 g/cm³

Good packing ability

2

Tapped Density

0.50 g/cm³

Acceptable

3

Carr’s Index

16%

Fair flow property

4

Hausner’s Ratio

1.19

Good flow

5

Angle of Repose

28°

Excellent flow

 

Table: Post-Granulation Evaluation Results

Sr. No.

Parameter

Result (Observed)

Interpretation

1

Appearance

Brown, uniform granules

Acceptable

2

Particle Size

250–850 µm

Uniform size distribution

3

Moisture Content

3.5%

Stable

4

Iron Content

3.2 mg/g

Good iron enrichment

5

In-vitro Release

85% in 60 min

Good release profile

6

Flow Property

Smooth flow

Easy handling

7

Solubility

Dispersible in water

Good availability

8

Stability Study

Stable for 3 months

No significant change observed

 

Table: Iron Estimation Result

Parameter

Result

Method Used

Iron Content

3.2 mg/g

AAS / UV method

CONCLUSION

Banana flower (Musa spp.) is considered a highly nutritious plant part and has great potential for use in functional foods and nutraceutical products. Research studies show that it contains a good balance of macronutrients, micronutrients, and bioactive compounds that are beneficial for human health.

One of the major nutritional advantages of banana flower is its high dietary fiber content. This fiber helps in maintaining proper digestion, improving bowel movement, and lowering the risk of chronic diseases such as heart problems and diabetes. According to Bhaskar et al. (2012), the fiber present also supports antioxidant activity and helps in regulating metabolism.

Apart from fiber, banana flower provides moderate levels of protein and carbohydrates, which makes it useful as a supplementary food ingredient. It also contains important vitamins like vitamin C and vitamin E, which act as antioxidants. These vitamins help protect the body from oxidative damage and strengthen the immune system.

Banana flower is also rich in essential minerals such as iron, calcium, magnesium, and potassium. The presence of iron makes it especially useful in preventing and managing iron deficiency anemia.

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REFERENCES

  1. Bhaskar JJ, Mahadevamma S, Chilkunda ND, Salimath PV. Banana flower and pseudostem: Dietary fiber and antioxidant capacity. J Agric Food Chem. 2012;60(1):427–432.
  2. Mohapatra D, Mishra S, Sutar N. Banana and its by-product utilization: An overview. J Sci Ind Res. 2010;69:323–329.
  3. Nagarajaiah SB, Prakash J. Chemical composition and antioxidant potential of banana flower. Food Res Int. 2011;44(7):1811–1816.
  4. Singh B, Singh JP, Kaur A, Singh N. Bioactive compounds and associated health benefits of banana. Food Chem. 2016;206:1–11.
  5. Saifullah M, et al. Nutritional properties and processing of banana flower for functional food applications. J Food Process Preserv. 2020;44(3):e14333.
  6. Pathak P, Mandal S, Dey A. Banana inflorescence: Its bio-prospects as an ingredient for functional foods. Trends Food Sci Technol. 2020;97:14–28.
  7. Kavya MH, Manasa R, Deepika M, Shivananjappa M. A review on banana flower: Nutritional composition, processed products and health benefits. IP J Nutr Metab Health Sci. 2023;6(3):110–115.
  8. Soni D, Saxena G. Complete nutrient profile of banana flower: A review. J Plant Sci Res. 2021;37(2):263–267.
  9. Naik SR, Kavya MH, Manasa R, Deepika M. Banana flower: Nutritional composition, processed products and health benefits. IP J Nutr Metab Health Sci. 2023.
  10. European Chemical Bulletin. Formulation and evaluation of capsules containing herbal extracts of Musa paradisiaca for treatment of anaemia. Eur Chem Bull. 2023;12(Special Issue 10):2130–2136.
  11. Aulton ME, Taylor K. Aulton’s Pharmaceutics: The design and manufacture of medicines. 5th ed. Elsevier; 2018.
  12. Allen LV, Popovich NG, Ansel HC. Ansel’s pharmaceutical dosage forms and drug delivery systems. 10th ed. Lippincott Williams & Wilkins; 2013.
  13. Lachman L, Lieberman HA, Kanig JL. The theory and practice of industrial pharmacy. 3rd ed. CBS Publishers; 2009.
  14. United States Pharmacopeia. USP 43–NF 38. United States Pharmacopeial Convention; 2020.
  15. ICH Guidelines. Stability testing of new drug substances and products Q1A(R2). International Council for Harmonisation; 2003

Reference

  1. Bhaskar JJ, Mahadevamma S, Chilkunda ND, Salimath PV. Banana flower and pseudostem: Dietary fiber and antioxidant capacity. J Agric Food Chem. 2012;60(1):427–432.
  2. Mohapatra D, Mishra S, Sutar N. Banana and its by-product utilization: An overview. J Sci Ind Res. 2010;69:323–329.
  3. Nagarajaiah SB, Prakash J. Chemical composition and antioxidant potential of banana flower. Food Res Int. 2011;44(7):1811–1816.
  4. Singh B, Singh JP, Kaur A, Singh N. Bioactive compounds and associated health benefits of banana. Food Chem. 2016;206:1–11.
  5. Saifullah M, et al. Nutritional properties and processing of banana flower for functional food applications. J Food Process Preserv. 2020;44(3):e14333.
  6. Pathak P, Mandal S, Dey A. Banana inflorescence: Its bio-prospects as an ingredient for functional foods. Trends Food Sci Technol. 2020;97:14–28.
  7. Kavya MH, Manasa R, Deepika M, Shivananjappa M. A review on banana flower: Nutritional composition, processed products and health benefits. IP J Nutr Metab Health Sci. 2023;6(3):110–115.
  8. Soni D, Saxena G. Complete nutrient profile of banana flower: A review. J Plant Sci Res. 2021;37(2):263–267.
  9. Naik SR, Kavya MH, Manasa R, Deepika M. Banana flower: Nutritional composition, processed products and health benefits. IP J Nutr Metab Health Sci. 2023.
  10. European Chemical Bulletin. Formulation and evaluation of capsules containing herbal extracts of Musa paradisiaca for treatment of anaemia. Eur Chem Bull. 2023;12(Special Issue 10):2130–2136.
  11. Aulton ME, Taylor K. Aulton’s Pharmaceutics: The design and manufacture of medicines. 5th ed. Elsevier; 2018.
  12. Allen LV, Popovich NG, Ansel HC. Ansel’s pharmaceutical dosage forms and drug delivery systems. 10th ed. Lippincott Williams & Wilkins; 2013.
  13. Lachman L, Lieberman HA, Kanig JL. The theory and practice of industrial pharmacy. 3rd ed. CBS Publishers; 2009.
  14. United States Pharmacopeia. USP 43–NF 38. United States Pharmacopeial Convention; 2020.
  15. ICH Guidelines. Stability testing of new drug substances and products Q1A(R2). International Council for Harmonisation; 2003

Photo
Swapnali Zambare
Corresponding author

Department of Pharmacognosy / Ashokrao Mane College of Pharmacy, Peth-Vadgaon / Shivaji University 416112, Maharashtra, India..

Photo
Akshada Deshmukh
Co-author

Department of Pharmacognosy / Ashokrao Mane College of Pharmacy, Peth-Vadgaon / Shivaji University 416112, Maharashtra, India..

Photo
Saeed Mulla
Co-author

Department of Pharmacognosy / Ashokrao Mane College of Pharmacy, Peth-Vadgaon / Shivaji University 416112, Maharashtra, India..

Photo
Suhani ware
Co-author

Department of Pharmacognosy / Ashokrao Mane College of Pharmacy, Peth-Vadgaon / Shivaji University 416112, Maharashtra, India..

Photo
Seema Thaware
Co-author

Department of Pharmacognosy / Ashokrao Mane College of Pharmacy, Peth-Vadgaon / Shivaji University 416112, Maharashtra, India..

Swapnali Zambare, Akshada Deshmukh, Saeed Mulla, Suhani ware, Seema Thaware , Review on Development and Evaluation of Banana Flower (Musa paradisiaca) as an Iron-Rich Nutraceutical Supplement, Int. J. of Pharm. Sci., 2026, Vol 4, Issue 4, 3986-3993, https://doi.org/10.5281/zenodo.19728680

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