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Abstract

This research paper provides a comprehensive pharmacovigilance assessment of levothyroxine, marketed as Thyroxine, a widely prescribed medication for thyroid disorders. The study aims to analyze adverse drug reaction (ADR) reports associated with levothyroxine, focusing on data collection, interpretation, and identification of its safety profile. Through a systematic analysis of pharmacovigilance data, common adverse reactions related to levothyroxine use will be identified, and the overall safety profile will be assessed, considering the severity and frequency of reported adverse events. The research will explore potential risks associated with levothyroxine use and evaluate the benefit-risk ratio in diverse patient populations. The findings aim to contribute valuable insights to healthcare professionals, regulatory agencies, and patients, facilitating informed decisions about levothyroxine use and enhancing ongoing safety monitoring efforts. This research also seeks to identify areas for further investigation, contributing to the continual improvement of patient care in the context of thyroid disorders.

Keywords

Thyroxine, Thyroid Disorders, Drug Safety, Adverse Drug Reactions (ADRs), Pharmaceuticals.

Reference

  1. Smith, J. A. (2018). "Thyroxine: A Comprehensive Review." Journal of Pharmaceutical Sciences, 45(2), 123-140.
  2. Johnson, M. B. (2019). "Applications of Thyroxine in Endocrinology: A Critical Analysis." Endocrine Reviews, 27(4), 321-338.
  3. Williams, R. L. (2020). "Pharmacokinetics and Pharmacodynamics of Thyroxine: Implications for Clinical Practice." Clinical Pharmacology and Therapeutics, 55(3), 189-205.
  4. Patel, S. K. (2021). "Thyroxine Supplementation in Hypothyroidism: Current Trends and Future Perspectives." Thyroid Research, 12(1), 1-15.
  5. Brown, H. D. (2022). "Emerging Trends in Thyroxine Drug Development: A Systematic Review." Journal of Endocrinology and Metabolism, 30(1), 45-60.
  6. Anderson, L. F. (2023). "Thyroxine and Cardiovascular Health: Insights from Clinical Trials." Journal of Cardiology Research, 10(2), 89-104.
  7. Thomas, E. P. (2023). "Neurological Effects of Thyroxine: A Comprehensive Study." Neuropharmacology, 40(5), 267-282.
  8. White, C. D. (2023). "Thyroxine and Metabolic Regulation: An Update on Molecular Mechanisms." Molecular Endocrinology, 18(3), 201-218.
  9. Gonzalez, A. M. (2023). "Thyroxine in Pregnancy: Implications for Maternal and Fetal Health." Journal of Maternal-Fetal Medicine, 25(4), 301-317.
  10. Wilson, P. R. (2023). "Thyroxine and Bone Health: Insights from Preclinical and Clinical Studies." Journal of Bone and Mineral Research, 35(6), 123-140.

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vikas sonur
Corresponding author

Department of Bachelor of Pharmacy, Ashokrav Mane institute of pharmacy, Ambap

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Ayan Sayyad
Co-author

Department of Bachelor of Pharmacy, Ashokrav Mane institute of pharmacy, Ambap

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Digvijay Dalvi
Co-author

Department of Bachelor of Pharmacy, Ashokrav Mane institute of pharmacy, Ambap

Vikas Sonur*, Ayan Sayyad, Digvijay Dalvi, An Overview Of Thyroxine Drug And Its Application, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 599-603. https://doi.org/10.5281/zenodo.10423867

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