Abstract

This review provides an in-depth analysis of the analgesic and anesthetic effects of clove, a spice derived from the flower buds of the Syzgium aromaticum tree 1. The active ingredient in clove oil, eugenol, has been identified as the primary compound responsible for these effects. The review covers the historical use of clove as a pain reliever and anaesthetic, the mechanisms of action of eugenol, and the clinical applications of clove oil in dentistry and traditional medicine. The review concludes with a discussion on future research directions in this field. Objective Results obtained from literature reviews and human studies have shown the analgesic effects of clove plant in toothache, and use of clove oil as painkiller.

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