1Department of Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka, INDIA.
Renal impairment is the inability of the kidneys to perform their excretory functions, which results in the retention of nitrogenous waste products in the blood. Infectious disease is recognized as an important complication among patients with renal impairment, contributing to excess morbidity and health care costs. Epidemiological research revealed that individuals with end-stage renal disease are more prone to develop infectious complications, which include urinary tract infection, pneumonia, and sepsis. These infections can be managed with the appropriate antibiotics. The objective of the study was to evaluate the utilization patterns of antibiotic in patients with renal impairment. A retrospective study was conducted by screening the medical records of 100 patients who fulfilled the inclusion criteria. Antibiotic utilization was analysed using Microsoft Excel. The mean age of the study participant 59.8 years with 67% male and 33?male. Majority of the patients were diagnosed with CKD (56%). Commonly utilized antibiotics were Inj. Meropenem (21.42%), Inj. Ceftriaxone (12.5%), T. Amoxicillin + Clavulanic acid (9.82%), Inj. Pipracillin + Tazobactam (9.82%).The rational use of antibiotics is critical for optimising clinical outcomes. The most commonly prescribed parenteral antibiotic was Injection Meropenem, while the most commonly prescribed oral antibiotic was Tablet Amoxicillin + Clavulanic acid.
Viresh K. Chandur, K. Anjali*, Ashitha Ephrem, Ramakrishna Shabaraya A., A Retrospective Study On Evaluation Of Antibiotic Utilization In Renal Impairment In A Tertiary Care Hospital In Dakshina Kannada District, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 11, 214-220. https://doi.org/10.5281/zenodo.10092365