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Abstract

This study explores formulating and evaluating an eco-friendly cockroach-repellent spray using essential oils as a sustainable alternative to conventional chemical pesticides. The growing concerns over synthetic insecticides' health and environmental risks have driven the need for natural, non-toxic pest control solutions. This research focuses on developing a plant-based repellent that effectively prevents cockroaches while minimizing ecological impact. The formulation process involves selecting essential oils known for their insect-repelling properties, such as clove, Tulsi, and vetiver. These oils were blended with a suitable carrier and emulsifying agents to ensure proper dispersion and effectiveness. The repellent’s efficacy was tested through controlled laboratory experiments, where the formulation was applied to cockroach- infested areas. Observations were made on the insects' behavior, repellent activity, and duration of effectiveness.The findings revealed that the formulated spray successfully repelled cockroaches, with higher concentrations of essential oils demonstrating greater efficacy. The repellent was found to be non-toxic and safe for human exposure, making it a viable alternative to synthetic pesticides. Additionally, the study highlighted the advantages of using essential oil-based formulations, including biodegradability, sustainability, and reduced risk of insecticide resistance. The study concludes that essential oil-based repellents can serve as an effective and environment friendly solution for cockroach control. Further research is recommended to optimize the formulation and assess its long-term effectiveness in real-world applications.

Keywords

Clove, Tulsi, Vetiver, Cockroaches, Repellency

Introduction

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Cockroaches are among the most common household pests and are known to act as vectors for various pathogenic microorganisms, contributing to food contamination and the spread of diseases¹. Their presence in domestic environments is associated with poor hygiene, allergic reactions, and respiratory disorders². Conventional chemical insecticides are widely used for cockroach control; however, their continuous usage has raised serious concerns due to toxicity, environmental pollution, and the development of insect resistance³.

In recent years, there has been a growing interest in the development of eco-friendly and sustainable pest control methods. Plant-based products, particularly essential oils, have gained attention due to their biodegradability, low toxicity, and broad-spectrum biological activities?. Essential oils derived from medicinal plants possess insecticidal, repellent, antimicrobial, and antioxidant properties, making them promising alternatives to synthetic pesticides?.

Among these, Syzygium aromaticum (clove) is rich in eugenol, a bioactive compound known for its strong insecticidal and repellent properties?. Chrysopogon zizanioides (vetiver) produces essential oil with long-lasting repellent activity due to its low volatility?. Ocimum tenuiflorum (tulsi) contains various phytoconstituents such as flavonoids, phenolics, and terpenoids, which contribute to its antimicrobial and insect-repellent effects?. Previous studies have demonstrated the effectiveness of these plant-derived oils against various insect species, including cockroaches??¹¹.

Despite the proven potential of individual essential oils, there is limited research on their combined formulation and evaluation as a stable, effective cockroach repellent spray¹². The synergistic effect of multiple essential oils may enhance repellency and prolong activity while maintaining safety for human use.

Therefore, the present study aims to formulate and evaluate an eco-friendly cockroach repellent spray using essential oils of clove, tulsi, and vetiver as a sustainable alternative to conventional chemical pesticides.

MATERIALS AND METHODS:

Fresh leaves of Ocimum tenuiflorum, dried flower buds of Syzygium aromaticum, and roots of Chrysopogon zizanioides were used for the study. Ethanol, distilled water, vinegar, lecithin, citric acid, ascorbic acid, and castor oil were used as reagents. All chemicals used were of analytical grade.14

Collection and Authentication

Leaves of Ocimum tenuiflorum were collected from local areas of Wayanad, Kerala. The plant material was authenticated by a qualified botanist from the Department of Botany, St. Mary’s College, Sulthan Bathery.

Extraction of Plant Material

The collected plant materials were shade-dried and powdered.

•           Hydro-distillation:

Dried clove buds and vetiver roots (100 g each) were subjected to hydro-distillation for 4–6 h using a round-bottom flask. The essential oils obtained were collected and stored in airtight containers.34,36

•           Soxhlet extraction:

Powdered leaves of Ocimum tenuiflorum were extracted using ethanol in a Soxhlet apparatus until complete extraction. The extract was collected and preserved for further analysis.18

Phytochemical Screening

The extracts were subjected to preliminary phytochemical screening for the detection of phenolic compounds, phytosterols, triterpenoids, and eugenol using standard chemical tests such as ferric chloride test, gelatin test, lead acetate test, Liebermann–Burchard test, Salkowski test, bromine water test, and potassium permanganate test.17,18

Formulation of Cockroach Repellent Spray

The repellent spray was prepared as an emulsion using aqueous and oil phases.

•           Aqueous phase:

Distilled water (50 ml) containing citric acid (0.1 g) and ascorbic acid (0.05 g) was mixed with tulsi extract (5 ml) and vinegar (5 ml).

•           Oil phase:

Clove oil (5 ml), vetiver oil (5 ml), castor oil (5 drops), and lecithin (1 ml) were mixed thoroughly.

The oil phase was slowly added to the aqueous phase with continuous stirring to form a stable emulsion. The final volume was adjusted to 100 ml using distilled water.44

Evaluation of Repellent Activity

Repellent activity was evaluated using a cardboard box method. The box was divided into treated and control areas. The formulation was sprayed on the treated side, while the control remained untreated. Ten cockroaches were introduced into the box, and observations were recorded at 1, 6, 24, and 48 h intervals based on their distribution.40,41

RESULTS AND DISCUSSION:

Results

1.         Macroscopic evaluation

Macroscopic evaluation confirmed the identity of plant materials based on their characteristic features. Clove buds were dark brown with a strong aroma, vetiver roots were fibrous with an earthy odor, and tulsi leaves were green, aromatic, and ovate in shape.

 

 

 
  

 

Fig1: Dried clove buds             Fig2: Dried vetiver roots          Fig 3: Tulsi leaves

 

2.         Microscopic evaluation

Microscopic analysis revealed the presence of characteristic anatomical features such as oil glands in clove, parenchymatous cells with oil globules in vetiver, and glandular trichomes in tulsi leaves.

 

 

Fig 4: TS of Vetiver root

 

 

 

 

Fig 5: TS of clove buds

 

 

 

Fig 6: TS of Tulsi leaf

 

3.         Phytochemical screening

Phytochemical screening indicated the presence of phenolic compounds, phytosterols, triterpenoids, and eugenol in the extracts, confirming their potential biological activity. The formulated spray was physically stable with no phase separation observed during the study period.

 

Table1: Phytochemical screening tests

 

S L N

O

CHEMICAL TESTS

INFERENCES

I.          Test For Phenolic Compounds

1

Ferric chloride test

+

2

Gelatin Test

+

3

Lead Acetate Test

+

4

Alkaline Reagent Test

+

5

Shinoda Test

+

II.         Test for phytosterols and triterpenoids

1

Liebermann’s Burchard Test

+

2

Salkowski Test

+

III.       Test for Eugenol

1

Ferric Chloride Test

+

2

Potassium permanganate Test

+

3

Bromine Water Test

+

 

4.         Evaluation of formulation

In the repellency test, cockroaches showed a clear tendency to avoid the treated area. At 1 h, initial movement towards the control area was observed, and by 24–48 h, most cockroaches remained in the control section, indicating significant repellent activity.

 

 

 

 

DISCUSSION

The results demonstrate that the formulated herbal spray possesses effective cockroach repellent activity. The presence of eugenol in clove oil contributes to strong insecticidal and neurotoxic effects. Vetiver oil provides prolonged action due to its low volatility, while tulsi enhances the repellent effect through its phytoconstituents such as flavonoids and terpenoids.

The synergistic effect of these essential oils plays a key role in improving the overall efficacy of the formulation. Compared to synthetic insecticides, the developed formulation is eco-friendly, biodegradable, and safe for human use.

These findings support the potential application of plant-based formulations as sustainable alternatives for household pest control.

REFERENCES

  1. Jagapriya J: Identification of bioactive compounds and pharmacognostic evaluation of Syzygium aromaticum and Syzygium cumini by GC-MS. World J Pharm Pharm Sci 2020; 9:1628–1638.
  2. Dubey A and Kumari M: Antimicrobial activity and phytochemical screening of Syzygium aromaticum, Thymus vulgaris, and Eucalyptus globulus. Microb Bioact 2024; 7:1–5.
  3. Sarker J and Islam M: Ethnomedicinal use and pharmacological properties of Syzygium aromaticum and Ocimum sanctum. 2022.
  4. Lim TK: Edible Medicinal and Non-Medicinal Plants. Springer, 2014.
  5. Chahal K et al.: Chemical composition and biological properties of Chrysopogon zizanioides. J Pharmacogn Phytochem 2015; 6:251–260.
  6. Grover M et al.: Pharmacognosy and pharmacological activities of Chrysopogon zizanioides. Environ Sci Pollut Res 2021; 28:1–26.
  7. Shah B and Seth AK: Textbook of Pharmacognosy and Phytochemistry. Elsevier, 2010.
  8. Bhattarai K et al.: Phytochemical constituents and bioactivities of Ocimum tenuiflorum. Sci World J 2024; 2024:8895039.
  9. Raina AP et al.: Chemical characterization of essential oil of Ocimum tenuiflorum. Genet Resour Crop Evol 2013; 60:1727–1735.
  10. Upadhyay AK et al.: Genome sequencing of Ocimum tenuiflorum. BMC Plant Biol 2015; 15:1–20.
  11. Sharawi SE et al.: Toxicity of clove oil against Periplaneta americana. Afr Entomol 2013; 21:324–332.

 

  1. Thavara U et al.: Repellent activity of essential oils against cockroaches. Southeast Asian J Trop Med Public Health 2007; 38:663–673.
  2. Appel AG et al.: Repellency and toxicity of mint oil to cockroaches. J Agric Urban Entomol 2001; 18:149–156.
  3. Kamaraj C et al.: Bioactive essential oils and insecticidal potential. 2024
  4. Deogade MS, Prasad KS. Standardisation of wild Krushnatulasi (Ocimum tenuiflorum Linn) leaf. International journal of ayurvedic medicine. 2019;10(1):52-61.
  5. Farman F, Martolia J, Painuly N. Pharmacognostic, ethnopharmacological, phytochemical screening of Cinnamomum verum and Ocimum tenuiflorum leaf extract for its antiseptic activity. Educ Adm Theory Pract. 2024;30.
  6. Ijinu TP, Jacob J, Sasikumar P, Varghese T, Nair RR, Pushpangadan P. Phytochemical Constituents and Pharmacology of Ocimum Tenuiflorum L. In Bioactives and pharmacology of Lamiaceae 2023 Oct 27 (pp. 389413). Apple Academic Press.
  7. Valsan A, Bose A, Kumar AA. Preliminary phytochemical screening of indigenous medicinal plants Ocimum tenuiflorum, Ocimum basilicum, and Ocimum gratissimum. Research Journal of Agricultural Sciences. 2022;13(4):925-30.
  8. Zahran EM, Abdelmohsen UR, Khalil HE, Desoukey SY, Fouad MA, Kamel MS. Diversity, phytochemical and medicinal potential of the genus Ocimum L. (Lamiaceae). Phytochemistry Reviews. 2020 Aug; 19:907-53.
  9. Yun S, Choi JH, Oh S, Kim M, Yi MH, Kang D, Jang YS, Lee IY, Yong TS, Kim J, Kim HC. Microbiome of laboratory-reared and environmentally collected cockroaches. Entomological Research. 2024 Apr;54(4): e12727.
  10. Iganga MI, Victor D. Bacteria infestation of cockroaches in Bali Metropolis, Taraba State, Nigeria. 2024; 12:48–56.
  11. Malik A, Mehmood K, Nadeem MS, Malik K. Plant-based repellents and insecticides for cockroach control: A comprehensive review. Journal of Pure and Applied Agriculture. 2023 Dec 4;8(3).
  12. Sharawi SE, Omara SM, Al-Ghamdi KM, Abd-Alla SM. Surface contact toxicity of clove and rosemary oils against American cockroach, Periplaneta americana (L.). African Entomology. 2013 Sep 1;21(2):324-32.
  13. Nagal RK. Development of Chalk from Selected Herbs as Cockroach (Periplaneta americana) Repellents. JPAIR Multidisciplinary Research. 2019 Jan 15;35(1):128-43.
  14. Rumah HM, Sani M, Mukhtar F. Multidrug-Resistant Gram-Negative Pathogens Transported by Cockroaches in Urban Residential Areas of Katsina Metropolis.
  15. Ayana Z, Yohannis M, Abera Z. Food-borne bacterial diseases in Ethiopia. Acad J Nutr. 2015;4(1):62-76.
  16. Manzoor F, Munir N, Ambreen A, Naz S. Efficacy of some essential oils against American cockroach Periplaneta americana (L.). Journal of Medicinal Plants Research. 2012 Feb 16;6(6):1065-9.
  17. Thoms EM, Robinson WH. Distribution and movement of the oriental cockroach (Orthoptera: Blattidae) around apartment buildings. Environmental entomology. 1987 Jun 1;16(3):731-7.
  18. Manzanares-Sierra A, Monsonís-Güell E, Gómez C, Abril S, MorenoGómez M. Essential Oils as Bioinsecticides Against Blattella germanica (Linnaeus, 1767): Evaluating Its Efficacy Under a Practical Framework. Insects. 2025 Jan18;16(1):98.
  19. Bar-Lev Viterbo A, Wexler JR, Mayost Lev-Ari O, Chipman AD. Early embryonic development of the German cockroach Blattella germanica. EvoDevo. 2024 Oct 26;15(1):14.
  20. Nasirian H. An overview of German cockroach, Blattella germanica, studies conducted in Iran. Pakistan Journal of biological sciences. 2010 Nov 15;13(22):1077.
  21. Kim T, Rust MK. Life history and biology of the invasive Turkestan cockroach (Dictyoptera: Blattidae). Journal of economic entomology. 2013 Dec 1;106(6):2428-32.
  22. ElDamir M. American cockroach management: practical strategies and solutions. 2024;3(1).
  23. Khalil AA, ur Rahman U, Khan MR, Sahar A, Mehmood T, Khan M. Essential oil eugenol: Sources, extraction techniques and nutraceutical perspectives. RSC advances. 2017;7(52):32669-81.
  24. Balasankar D, Vanilarasu K, Preetha PS, Rajeswari S, Umadevi M, Bhowmik D. Traditionaland medicinal uses of vetiver. J. Med. Plants Stud. 2013;1(3):191-200.
  25. Bahri S, Raharjo TT, Ambarwati Y. Isolation and Identification of Terpenoid Compound from Vetiver Grass-Root (Vetiveria zizanioides Stapf) as a Repellent against Termite (Cyrptotermes sp.) through Bioactivity Assay. In Journal of Physics: Conference Series 2021 (Vol. 1751, No. 1, p. 012101). IOP Publishing.
  26. Sara S. Mosquito repellent activity and toxicity of flower buds (cloves) of Syzygium aromaticum Linn. Am J Pharm Health Res. 2014; 2: 55–62.
  27. Susurluk H. Potential use of essential oils from Origanum vulgare and Syzygium aromaticum to control Tetranychus urticae Koch (Acari: Tetranychidae) on two host plant species. PeerJ. 2023 Jan 20; 11: e 14475.
  28. Yoon C, Kang SH, Yang JO, Noh DJ, Indiragandhi P, Kim GH. Repellent activity of citrus oils against the cockroaches Blattella germanica, Periplaneta americana and P. fuliginosa. Journal of Pesticide Science. 2009 May 25;34(2):77-88.
  29. Thavara U, Tawatsin A, Bhakdeenuan P, Wongsinkongman P, Boonruad T, Bansiddhi J, Chavalittumrong P, Komalamisra N, Siriyasatien P, Mulla MS. Repellent activity of essential oils against cockroaches (Dictyoptera: Blattidae, Blattellidae, and Blaberidae) in Thailand. Southeast Asian J Trop Med Public Health. 2007 Jul 1;38(4):663-73.
  30. Appel AG, Gehret MJ, Tanley MJ. Repellency and toxicity of mint oil to American and German cockroaches (Dictyoptera: Blattidae and Blattellidae). J. Agric. Urban Entomol. 2001 Jul 1;18(3):149-56.
  31. Dubey A, Kumari M. Antimicrobial activity, Phytochemical Screening of Crude Extracts, and Essential Constituents of Syzygium Aromaticum, Tymus Vulgaris and Eucalyptus Globulus on Selected Pathogens. Microbial Bioactives. 2024 Jun 20;7(1):1-5.
  32. Malav P, Pandey A, Bhatt KC, Gopala Krishnan S, Bisht IS. Morphological variability in holy basil (Ocimum tenuiflorum L.) from India. Genetic Resources and Crop Evolution. 2015 Dec; 62:1245-56.
  33. Bhattarai K, Bhattarai R, Pandey RD, Paudel B, Bhattarai HD. A Comprehensive Review of the Phytochemical Constituents and Bioactivities of Ocimum tenuiflorum. The Scientific World Journal. 2024;2024(1):8895039.
  34. Chahal K, Bhardwaj U, Kaushal S, Sandhu AK. Chemical composition andbiological properties of Chrysopogon zizanioides (L.) Roberty syn. Vetiveria zizanioides (L.) Nash – a review. Int J Med Aromat Plants. 2015; 6:251–60.

Reference

  1. Jagapriya J: Identification of bioactive compounds and pharmacognostic evaluation of Syzygium aromaticum and Syzygium cumini by GC-MS. World J Pharm Pharm Sci 2020; 9:1628–1638.
  2. Dubey A and Kumari M: Antimicrobial activity and phytochemical screening of Syzygium aromaticum, Thymus vulgaris, and Eucalyptus globulus. Microb Bioact 2024; 7:1–5.
  3. Sarker J and Islam M: Ethnomedicinal use and pharmacological properties of Syzygium aromaticum and Ocimum sanctum. 2022.
  4. Lim TK: Edible Medicinal and Non-Medicinal Plants. Springer, 2014.
  5. Chahal K et al.: Chemical composition and biological properties of Chrysopogon zizanioides. J Pharmacogn Phytochem 2015; 6:251–260.
  6. Grover M et al.: Pharmacognosy and pharmacological activities of Chrysopogon zizanioides. Environ Sci Pollut Res 2021; 28:1–26.
  7. Shah B and Seth AK: Textbook of Pharmacognosy and Phytochemistry. Elsevier, 2010.
  8. Bhattarai K et al.: Phytochemical constituents and bioactivities of Ocimum tenuiflorum. Sci World J 2024; 2024:8895039.
  9. Raina AP et al.: Chemical characterization of essential oil of Ocimum tenuiflorum. Genet Resour Crop Evol 2013; 60:1727–1735.
  10. Upadhyay AK et al.: Genome sequencing of Ocimum tenuiflorum. BMC Plant Biol 2015; 15:1–20.
  11. Sharawi SE et al.: Toxicity of clove oil against Periplaneta americana. Afr Entomol 2013; 21:324–332.

 

  1. Thavara U et al.: Repellent activity of essential oils against cockroaches. Southeast Asian J Trop Med Public Health 2007; 38:663–673.
  2. Appel AG et al.: Repellency and toxicity of mint oil to cockroaches. J Agric Urban Entomol 2001; 18:149–156.
  3. Kamaraj C et al.: Bioactive essential oils and insecticidal potential. 2024
  4. Deogade MS, Prasad KS. Standardisation of wild Krushnatulasi (Ocimum tenuiflorum Linn) leaf. International journal of ayurvedic medicine. 2019;10(1):52-61.
  5. Farman F, Martolia J, Painuly N. Pharmacognostic, ethnopharmacological, phytochemical screening of Cinnamomum verum and Ocimum tenuiflorum leaf extract for its antiseptic activity. Educ Adm Theory Pract. 2024;30.
  6. Ijinu TP, Jacob J, Sasikumar P, Varghese T, Nair RR, Pushpangadan P. Phytochemical Constituents and Pharmacology of Ocimum Tenuiflorum L. In Bioactives and pharmacology of Lamiaceae 2023 Oct 27 (pp. 389413). Apple Academic Press.
  7. Valsan A, Bose A, Kumar AA. Preliminary phytochemical screening of indigenous medicinal plants Ocimum tenuiflorum, Ocimum basilicum, and Ocimum gratissimum. Research Journal of Agricultural Sciences. 2022;13(4):925-30.
  8. Zahran EM, Abdelmohsen UR, Khalil HE, Desoukey SY, Fouad MA, Kamel MS. Diversity, phytochemical and medicinal potential of the genus Ocimum L. (Lamiaceae). Phytochemistry Reviews. 2020 Aug; 19:907-53.
  9. Yun S, Choi JH, Oh S, Kim M, Yi MH, Kang D, Jang YS, Lee IY, Yong TS, Kim J, Kim HC. Microbiome of laboratory-reared and environmentally collected cockroaches. Entomological Research. 2024 Apr;54(4): e12727.
  10. Iganga MI, Victor D. Bacteria infestation of cockroaches in Bali Metropolis, Taraba State, Nigeria. 2024; 12:48–56.
  11. Malik A, Mehmood K, Nadeem MS, Malik K. Plant-based repellents and insecticides for cockroach control: A comprehensive review. Journal of Pure and Applied Agriculture. 2023 Dec 4;8(3).
  12. Sharawi SE, Omara SM, Al-Ghamdi KM, Abd-Alla SM. Surface contact toxicity of clove and rosemary oils against American cockroach, Periplaneta americana (L.). African Entomology. 2013 Sep 1;21(2):324-32.
  13. Nagal RK. Development of Chalk from Selected Herbs as Cockroach (Periplaneta americana) Repellents. JPAIR Multidisciplinary Research. 2019 Jan 15;35(1):128-43.
  14. Rumah HM, Sani M, Mukhtar F. Multidrug-Resistant Gram-Negative Pathogens Transported by Cockroaches in Urban Residential Areas of Katsina Metropolis.
  15. Ayana Z, Yohannis M, Abera Z. Food-borne bacterial diseases in Ethiopia. Acad J Nutr. 2015;4(1):62-76.
  16. Manzoor F, Munir N, Ambreen A, Naz S. Efficacy of some essential oils against American cockroach Periplaneta americana (L.). Journal of Medicinal Plants Research. 2012 Feb 16;6(6):1065-9.
  17. Thoms EM, Robinson WH. Distribution and movement of the oriental cockroach (Orthoptera: Blattidae) around apartment buildings. Environmental entomology. 1987 Jun 1;16(3):731-7.
  18. Manzanares-Sierra A, Monsonís-Güell E, Gómez C, Abril S, MorenoGómez M. Essential Oils as Bioinsecticides Against Blattella germanica (Linnaeus, 1767): Evaluating Its Efficacy Under a Practical Framework. Insects. 2025 Jan18;16(1):98.
  19. Bar-Lev Viterbo A, Wexler JR, Mayost Lev-Ari O, Chipman AD. Early embryonic development of the German cockroach Blattella germanica. EvoDevo. 2024 Oct 26;15(1):14.
  20. Nasirian H. An overview of German cockroach, Blattella germanica, studies conducted in Iran. Pakistan Journal of biological sciences. 2010 Nov 15;13(22):1077.
  21. Kim T, Rust MK. Life history and biology of the invasive Turkestan cockroach (Dictyoptera: Blattidae). Journal of economic entomology. 2013 Dec 1;106(6):2428-32.
  22. ElDamir M. American cockroach management: practical strategies and solutions. 2024;3(1).
  23. Khalil AA, ur Rahman U, Khan MR, Sahar A, Mehmood T, Khan M. Essential oil eugenol: Sources, extraction techniques and nutraceutical perspectives. RSC advances. 2017;7(52):32669-81.
  24. Balasankar D, Vanilarasu K, Preetha PS, Rajeswari S, Umadevi M, Bhowmik D. Traditionaland medicinal uses of vetiver. J. Med. Plants Stud. 2013;1(3):191-200.
  25. Bahri S, Raharjo TT, Ambarwati Y. Isolation and Identification of Terpenoid Compound from Vetiver Grass-Root (Vetiveria zizanioides Stapf) as a Repellent against Termite (Cyrptotermes sp.) through Bioactivity Assay. In Journal of Physics: Conference Series 2021 (Vol. 1751, No. 1, p. 012101). IOP Publishing.
  26. Sara S. Mosquito repellent activity and toxicity of flower buds (cloves) of Syzygium aromaticum Linn. Am J Pharm Health Res. 2014; 2: 55–62.
  27. Susurluk H. Potential use of essential oils from Origanum vulgare and Syzygium aromaticum to control Tetranychus urticae Koch (Acari: Tetranychidae) on two host plant species. PeerJ. 2023 Jan 20; 11: e 14475.
  28. Yoon C, Kang SH, Yang JO, Noh DJ, Indiragandhi P, Kim GH. Repellent activity of citrus oils against the cockroaches Blattella germanica, Periplaneta americana and P. fuliginosa. Journal of Pesticide Science. 2009 May 25;34(2):77-88.
  29. Thavara U, Tawatsin A, Bhakdeenuan P, Wongsinkongman P, Boonruad T, Bansiddhi J, Chavalittumrong P, Komalamisra N, Siriyasatien P, Mulla MS. Repellent activity of essential oils against cockroaches (Dictyoptera: Blattidae, Blattellidae, and Blaberidae) in Thailand. Southeast Asian J Trop Med Public Health. 2007 Jul 1;38(4):663-73.
  30. Appel AG, Gehret MJ, Tanley MJ. Repellency and toxicity of mint oil to American and German cockroaches (Dictyoptera: Blattidae and Blattellidae). J. Agric. Urban Entomol. 2001 Jul 1;18(3):149-56.
  31. Dubey A, Kumari M. Antimicrobial activity, Phytochemical Screening of Crude Extracts, and Essential Constituents of Syzygium Aromaticum, Tymus Vulgaris and Eucalyptus Globulus on Selected Pathogens. Microbial Bioactives. 2024 Jun 20;7(1):1-5.
  32. Malav P, Pandey A, Bhatt KC, Gopala Krishnan S, Bisht IS. Morphological variability in holy basil (Ocimum tenuiflorum L.) from India. Genetic Resources and Crop Evolution. 2015 Dec; 62:1245-56.
  33. Bhattarai K, Bhattarai R, Pandey RD, Paudel B, Bhattarai HD. A Comprehensive Review of the Phytochemical Constituents and Bioactivities of Ocimum tenuiflorum. The Scientific World Journal. 2024;2024(1):8895039.
  34. Chahal K, Bhardwaj U, Kaushal S, Sandhu AK. Chemical composition andbiological properties of Chrysopogon zizanioides (L.) Roberty syn. Vetiveria zizanioides (L.) Nash – a review. Int J Med Aromat Plants. 2015; 6:251–60.

Photo
Anu Jagajith A.
Corresponding author

Department of Pharmacognosy, Dr Moopen's College of Pharmacy, Wayanad

Photo
Anusree Prakash
Co-author

Department of Pharmacognosy, Dr Moopen's College of Pharmacy, Wayanad

Photo
Fathimath Zuhara MR
Co-author

Department of Pharmacognosy, Dr Moopen's College of Pharmacy, Wayanad

Photo
Adithya Vismaya
Co-author

Department of Pharmacognosy, Dr Moopen's College of Pharmacy, Wayanad

Photo
Dr Lal Prasanth M. L.
Co-author

Department of Pharmacognosy, Dr Moopen's College of Pharmacy, Wayanad

Anusree Prakash, Fathimath Zuhara MR, Adithya Vismaya, Anu Jagajith A., Dr Lal Prasanth M. L., Formulation And Evaluation of An Eco-Friendly Cockroach Repellent Spray Using Essential Oils: A Sustainable Alternative to Conventional Pesticides, Int. J. of Pharm. Sci., 2026, Vol 4, Issue 4, 3381-3388, https://doi.org/10.5281/zenodo.19676229

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