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Abstract

Gel‘s are the preparations used to enhance the human appearance. The aim of the present research was to formulate the gel for the purpose of whitening, Moistening, Nourishing, lightening & Treatment of various diseases of the skin. Different gelling agent; HPMC, CMC, AEROSIL. Active pharmaceutical ingredients TACROLIMUS taken. Different types of formulations gel namely F1 to F6 were formulated by incorporating different concentrations of ingredients. The evaluations of all formulations (F1 to F6) were done on different parameters like, irritancy, and consistency were examined. Formulations showed good consistency, homogeneity, appearance, spread ability, no evidence of phase separation and ease of removal. F2 showing 99.81±0.044 drug content. Thus gel formulation is safe to use was proved and it can be used as the provision of a barrier to protect skin.

Keywords

Tacrolimus, Gels, Polymer

Reference

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L. Gopi
Corresponding author

Aadhibhagawan College Of Pharmacy, Rantham, T. V. malai, Tamilnadu.

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B. Priyanka
Co-author

Aadhibhagawan College Of Pharmacy, Rantham, T. V. malai, Tamilnadu.

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D. Raja
Co-author

Aadhibhagawan College Of Pharmacy, Rantham, T. V. malai, Tamilnadu.

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M. Priya
Co-author

Aadhibhagawan College Of Pharmacy, Rantham, T. V. malai, Tamilnadu.

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R. Priyadharshini
Co-author

Aadhibhagawan College Of Pharmacy, Rantham, T. V. malai, Tamilnadu.

L. Gopi*, R. Priyadharshini, M. Priya, B. Priyanka, D. Raja, K. Ramesh, Aadhibhagawan College Of Pharmacy, Rantham, T. V. malai, Tamilnadu, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 7, 162-169. https://doi.org/10.5281/zenodo.8114004

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